Results 171 to 180 of about 75,592 (343)

Steroid 21-hydroxylase deficiency dysregulates essential molecular pathways of metabolism and energy provision. [PDF]

Biol Open
Bacila I, Oberski L, Li N, Storbeck KH, Cunliffe VT, Krone N.   +5 more
europepmc   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

Comprehensive characterization of 21-hydroxylase deficiency in a Chinese pediatric cohort: phenotype, steroid profiles and genetics. [PDF]

Front Endocrinol (Lausanne)
Chong H, Xue G, Pi Y, Zhang Y, Li Y, Xing Y, Chen B, Zhang H.   +7 more
europepmc   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

Journal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac, Milica Milutinović, Dragana Matekalo, Neda Popović, Luka Petrović, Uroš Gašić, Marijana Skorić, Branislav Šiler, Tamara Lukić, Ana Stupar, Slavica Dmitrović, Jasmina Nestorović Živković, Biljana Filipović, Jelena Božunović, Miloš Todorović, Danijela Mišić   +15 more
wiley   +1 more source

Adrenal Venous Sampling Aids in Distinguishing 17-Hydroxyprogesterone Hypersecreting Adrenal Cortical Adenomas from Non-Classical 21-Hydroxylase Deficiency. [PDF]

Diagnostics (Basel)
Qiu R, Yang T, Shang C, Zhu W, Zheng F.
europepmc   +1 more source

Corticotropin‐Releasing Hormone (CRH) in Murine Narcolepsy: What Do Genetic and Immune Models Tell Us?

Journal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy type 1 is a chronic sleep disorder of putative autoimmune aetiology, primarily caused by the loss of orexin‐producing neurons in the hypothalamus. An additional 88% reduction in corticotropin‐releasing hormone‐immunoreactive neurons of the paraventricular nucleus has been recently observed in post‐mortem brains of individuals with ...
J. Zhou, S. Melzi, A. L. Morel, B. Georges, T. E. Scammell, G. J. Lammers, R. Fronczek, C. Peyron   +7 more
wiley   +1 more source

Cognitive outcome of offspring from dexamethasone-treated pregnancies at risk for congenital adrenal hyperplasia due to 21-hydroxylase deficiency

, 2012
Heino F. L. Meyer‐Bahlburg, Curtis Dolezal, Rita Haggerty, Michael E. Silverman, Maria I. New   +4 more
openalex   +2 more sources

Functional Characterization of Two Novel Point Mutations in theCYP21Gene Causing Simple Virilizing Forms of Congenital Adrenal Hyperplasia Due to 21-Hydroxylase Deficiency [PDF]

, 2005
Nils Krone, Felix G. Riepe, Joachim Grötzinger, Carl‐Joachim Partsch, Wolfgang G. Sippell   +4 more
openalex   +1 more source

Starch synthesis in Brachypodium distachyon endosperm occurs in dynamic, connected amyloplast compartments

New Phytologist, EarlyView.
Summary The morphology of starch granules is a major determinant of the functional and nutritional properties of starch and is highly variable among cereal species. Much of this morphological variation stems from differences in the spatial and temporal patterns of starch granule initiation in amyloplasts during grain development.
Lara Esch, Qi Yang Ngai, Sergio G. Lopez, J. Elaine Barclay, Inmaculada Hernández‐Pinzón, Matthew J. Moscou, David Seung   +6 more
wiley   +1 more source

A Case of 21-hydroxylase Deficiency with Massive Bilateral Adrenal Masses

, 2023
Işılay Kalan Sarı, Ceren Erdoğan Eroğlu   +1 more
openalex   +2 more sources