Results 71 to 80 of about 57,151 (301)
Nonclassical 21-Hydroxylase Deficiency [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2006 AbstractContext: Nonclassical congenital adrenal hyperplasia (CAH) owing to steroid 21-hydroxylase deficiency (NC21OHD) is the most frequent of all autosomal recessive genetic diseases, occurring in one in 100 persons in the heterogeneous New York City population. NC21OHD occurs with increased frequency in certain ethnic groups, such as Ashkenazi Jews,
openaire +1 more source
Advanced Science, EarlyView.A sprayable near‐infrared‐activated nanoplatform incorporating MXene, ZnHCF nanozyme, and deferoxamine efficiently breaks the vicious cycle of diabetic wounds. Upon irradiation, interfacial electron transfer and photothermal effects enhance multi‐enzyme activity, enabling explosive ROS elimination, alleviation of hypoxia, and controlled DFO release ...
Jiahao Guo +5 more
wiley +1 more source
Long-read sequencing solves complex structure of CYP21A2 in a large 21-hydroxylase deficiency cohort_Supplementary materials [PDF]
Long-read sequencing solves complex structure of CYP21A2 in a large 21-hydroxylase deficiency cohort_Supplementary ...
Wenjuan Qiu (11161892) +3 more
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Advanced Science, EarlyView.Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Glucocorticoid induced osteoporosis in children with 21-hydroxylase deficiency [PDF]
, 2013 21-Hydroxylase deficiency (21-OHD) is the most common cause of congenital adrenal hyperplasia (CAH), resulting from deletions or mutations of the P450 21-hydroxylase gene (CYP21A2).
GRANO, Maria +7 more
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Management of 21 hydroxylase deficiency salt-wasting form of congenital adrenal hyperplasia
Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012 DOI: http://dx.doi.org/10.4038/sjdem.v1i1.4186 Sri Lanka Journal of Diabetes Endocrinology and Metabolism 2011; 1: 28-29
KSH de Silva
doaj +1 more source
Advanced Science, EarlyView.In the pathological state of PD induced by MPP+, the upregulated PRMT9 in dopaminergic neurons translocates into mitochondrion and interacts with DUSP26 and catalyzes its arginine methylation, leading to the ubiquitin‐proteasomal degradation of DUSP26 mediated by Trim32.
Tengfei Liu +13 more
wiley +1 more source
H62L Mutation of CYP21A2 Identified in the Non-classical Form of 21-Hydroxylase Deficiency [PDF]
, 2009 Neonatal mass screening for congenital adrenal hyperplasia (CAH) has been performed in Japan since 1989.
Toru Kikuchi +5 more
core
Pregnancy risk of women with non-classical 21OH hydroxylase deficiency [PDF]
, 2020 Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency is a complicated condition genetically, clinically, and treatment wise. We provide, in this article, a table and a detailed explanation for our calculations, for a newborn risk of ...
Ohad Cohen, Ilany Jacob
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Angewandte Chemie, EarlyView.Achieving selective (sp3)C–H hydroxylation can streamline the synthesis of complex organic molecules. Biocatalysis presents an opportunity to realize this transformation, however, identifying useful enzymes that enable synthetic strategies can be a challenge due to limitations in enzyme substrate scope.
Gonzalo J. Villegas Rodríguez +5 more
wiley +2 more sources