Results 101 to 110 of about 29,784,966 (285)
Spartan Daily, October 22, 1993 [PDF]
, 1993 Volume 101, Issue 39https://scholarworks.sjsu.edu/spartandaily/8467/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Spartan Daily, February 22, 1949 [PDF]
, 1949 Volume 37, Issue 86https://scholarworks.sjsu.edu/spartandaily/11200/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Spartan Daily, May 22, 1956 [PDF]
, 1956 Volume 43, Issue 140https://scholarworks.sjsu.edu/spartandaily/12348/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Spartan Daily, April 22, 1986 [PDF]
, 1986 Volume 86, Issue 54https://scholarworks.sjsu.edu/spartandaily/7443/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Spartan Daily, September 22, 1999 [PDF]
, 1998 Volume 113, Issue 16https://scholarworks.sjsu.edu/spartandaily/9445/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source