Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
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Effects of St. John's Wort extract on the release of paracrine markers and neurite outgrowth in mouse hippocampal HT-22 neuronal cells co-cultured with SIM-A9 microglia. [PDF]
Bonaterra GA +8 more
europepmc +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Michaelis & Meier, Hamburg, Kleiderstoff, Beduinen, Knackstedt & Co., Hamburg 22
MICHAELIS & MEIER, HAMBURG, KLEIDERSTOFF, BEDUINEN, KNACKSTEDT & CO., HAMBURG 22 Michaelis & Meier, Hamburg, Kleiderstoff, Beduinen, Knackstedt & Co., Hamburg 22 ( -
Knackstedt & Co., Hamburg 22 +1 more
core +1 more source
BODIPY-tagged β-lactams as selective quenched activity-based probes to target human neutrophil elastase. [PDF]
Felix R +10 more
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Physical Education Complex Groundbreaking Ceremony TV Coverage, (1980)
This is a Springfield Channel 22 news report video of the Groundbreaking Ceremony of Springfield College's new Physical Education (PE) Complex. It starts with a newscaster, Dave Madsen, announcing the story and then goes out to the site with Ed Kennedy ...
Channel 22 (Springfield, Mass.);
core
Michaelis & Meier, Hamburg, Kleiderstoffe, Baschkiren, Knackstedt & Co., Hamburg 22
MICHAELIS & MEIER, HAMBURG, KLEIDERSTOFFE, BASCHKIREN, KNACKSTEDT & CO., HAMBURG 22 Michaelis & Meier, Hamburg, Kleiderstoffe, Baschkiren, Knackstedt & Co., Hamburg 22 ( -
Knackstedt & Co., Hamburg 22 +1 more
core +1 more source
Long-Term Efficacy of Restricted Quantitative Superior Placement Technique in Total Hip Arthroplasty for Severe Developmental Dysplasia of the Hip: An 8- to 10-Year Follow-Up of a Prospective Randomized Controlled Trial. [PDF]
Li S +9 more
europepmc +1 more source

