Results 151 to 160 of about 29,978,210 (287)

Population health and implementation outcomes of self-testing for SARS-CoV-2 using antigen detecting diagnostics: a systematic review and meta-analysis. [PDF]

EClinicalMedicine
Brümmer LE, Faehling V, McGrath S, Zorger AM, Worbes K, Erdmann C, Tolle H, Katzenschlager S, Yerlikaya S, Grilli M, Pollock NR, Erkosar B, Mace A, Ongarello S, Johnson CC, Sacks JA, Cunningham J, Skoetz N, Denkinger CM, Lee RA.   +19 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nutrition Outcomes and Interventions in Older People in Africa: A Systematic Umbrella and Scoping Review. [PDF]

Nutr Rev
Manyara AM, Manyanga T, Naidoo S, Mattick K, Chingono R, Pearson GME, Babatunde O, Naidoo N, Ward KA, Gregson CL.   +9 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Redakcinė kolegija ir turinys

Aktualu Rytoj, 2022
Aktualu rytoj, 2022, t. 2, Nr. 22
doaj  

Mumps disease and vaccination in Africa: A scoping review. [PDF]

Hum Vaccin Immunother
Gobe I, Mogowa T, Kadimo K, Tlhakanelo JT, Motswaledi M.   +4 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Scottish Studies, Volume 22 (1978): Full Volume

Scottish Studies, 1978
[Editor]
doaj  

Aiolos and Eos drive distinct human TH17 functional states. [PDF]

Cell Mol Life Sci
Cerboni S, Mohammadnezhad L, Agrawal K, Budida R, Papa I, Gaggero S, Dulong J, Cole A, Mezger A, Yan B, Zhang Z, Israelsson E, Volkov P, Li S, Caceres EF, Leprohon M, Azgomi MS, Cui Y, Salemio S, Firth M, Wigge L, Rudin A, Grindebacke H, Maresca M, Paulos C, Morschhauser F, Manier S, Kazemian M, Laurence A, Hühn M, Gehrmann U, Tarte K, Mitra S.   +32 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source