Results 31 to 40 of about 64,240 (265)

Rates of Nonunion for Different Joints after Foot And Ankle Surgery: A Review of 2301 Fusions

Foot & Ankle Orthopaedics, 2019
Category: Ankle, Ankle Arthritis, Hindfoot, Midfoot/Forefoot Introduction/Purpose: Nonunion after fusion results in ongoing pain and a request for repeat surgery in many patients. Nonunion is therefore a failure of the primary surgery.
A. Younger, A. Veljkovic, K. Wing, M. Penner, H. Qian, H. Wong   +5 more
semanticscholar   +1 more source

Non-Invasive Regional Neurochemical Profiling of Zebrafish Brain Using Localized Magnetic Resonance Spectroscopy at 28.2 T

Molecules
Localized 1H magnetic resonance spectroscopy (MRS) is a powerful tool in pre-clinical and clinical neurological research, offering non-invasive insight into neurochemical composition in localized brain regions.
Rico Singer, Wanbin Hu, Li Liu, Huub J. M. de Groot, Herman P. Spaink, A. Alia   +5 more
doaj   +1 more source

Die Königsteiner Empfehlung – Empfehlung für die Begutachtung der Lärmschwerhörigkeit – BK-Nr. 2301

ASU Arbeitsmedizin Sozialmedizin Umweltmedizin
Die Begutachtung der Lärmschwerhörigkeit (BK 2301) richtet sich nach der Königsteiner Empfehlung (KE), deren 1. Auflage 1974 als Königsteiner Merkblatt (KM) erschien.
E. Meister, T. Brusis
semanticscholar   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

BIT 2301 Research Methodology [PDF]

, 2016
BIT 2301 Research ...
Murang'a University of Technology
core  

A Search for Variable Stars and Planetary Occultations in NGC 2301. I. Techniques [PDF]

, 2005
We observed the young open cluster NGC 2301 for 14 nights in 2004 February using the orthogonal transfer CCD camera OPTIC. We used point‐spread function shaping techniques (“square stars”) during the observations, allowing us to obtain a larger dynamic ...
J. Tonry, S. Howell, M. Everett, S. Rodney, M. Willman, C. VanOutryve   +5 more
semanticscholar   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source

SMA 2301 Real analysis [PDF]

, 2015
SMA 2301 Real ...
Murang'a University of Technology
core  

The Transgenerational Impact of High-Fat Diet and Diabetic Pregnancy on Embryonic Transcriptomics and Mitochondrial Health

Biomedicines
Background/Objectives: Overnutrition increases comorbidities such as gestational diabetes during pregnancy that can have detrimental consequences for both parent and progeny. We previously reported that high-fat (HF) diet and late-gestation diabetes (DM)
Abigail K. Klein, Benjamin P. Derenge, Malini Mukherjee, Srikrishna P. Reddy, Tricia D. Larsen, Prathapan Ayyappan, Tyler C. T. Gandy, Kyle M. Siemers, Michael S. Kareta, Michelle L. Baack   +9 more
doaj   +1 more source

Discovery of SD-2301 as a Highly Potent and Selective PROTAC STAT3 Degrader Capable of Achieving Complete Tumor Regression with Single Administration

Journal of Medicinal Chemistry
STAT3 is a promising therapeutic target for human cancers and other diseases. Herein, we report our development of novel STAT3 proteolysis-targeting chimera degraders using high-affinity STAT3 and Von Hippel-Lindau 1 ligands, which led to the discovery ...
R. Acharyya, Longchuan Bai, Haibin Zhou, Dimin Wu, Mi Wang, Hoda Metwally, D. McEachern, Meilin Wang, Bo Wen, Duxin Sun, Shaomeng Wang   +10 more
semanticscholar   +1 more source