Results 101 to 110 of about 27,833,629 (262)

Analysis of Matrix Metalloproteinase-2 (MMP-2) and Matrix Metalloproteinase-9 (MMP-9) Levels in Breast Cancer Patients [PDF]

, 2014
Breast cancer is one of the death cause in women and more than one million cases reported in\ud worldwide. World Health Organisation reported almost 460.000 women dead by breast\ud cancer in 2008.
Uleng
core  

Perspectives on the 2 × 2 Matrix: Solving Semantically Distinct Problems Based on a Shared Structure of Binary Contingencies. [PDF]

Front Psychol, 2020
Neth H, Gradwohl N, Streeb D, Keim DA, Gaissmaier W.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

FB 2 Lesefassung Studienordnung BA Maschinenbau 14.06.2006 bis 2. AEO

, 2020
im Fachbereich Ingenieurwissenschaften II vom 14. Juni 2006 unter Berücksichtigung der 1. Änderungsordnung vom 14. Februar 2007 und der 2. Änderungsordnung vom 17.
Fachbereich 2: Ingenieurwissenschaften II
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

FB 2 Lesefassung Studienordnung MA Fahrzeugtechnik 16.4.08 bis 2. AEO

, 2020
im Fachbereich Ingenieurwissenschaften II vom 16. April 2008 unter Berücksichtigung der 1. Änderungsordnung vom 15. Juli 2009 und der 2. Änderungsordnung vom 14.
Fachbereich 2: Ingenieurwissenschaften II
core   +1 more source

Two miniatures relating the 2 × 2 minors of a square matrix and the symmetric group

Extracta Mathematicae
In the first miniature we recall a puzzle proposed by Martin Gardner in 1957 and refreshed by Blasco in 2014. We prove some properties of the matrices involved. We show that Gardner magical matrices are tropically singular.
Marı́a Jesús de la Puente
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source