Results 41 to 50 of about 4,042,033 (199)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Trajectory of left ventricular geometry and diastolic dysfunction in hereditary transthyretin cardiac amyloidosis

open access: yesESC Heart Failure, 2021
Amyloid transthyretin (ATTR) depositions cause left ventricular (LV) hypertrophy, diastolic dysfunction, and heart failure. The time course of changes in LV geometry and diastolic dysfunction has not been fully reported in patients with ATTR ...
Tatsuya Akatsuka   +5 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Cayley's hyperdeterminant, the principal minors of a symmetric matrix and the entropy region of 4 Gaussian random variables [PDF]

open access: yes, 2009
It has recently been shown that there is a connection between Cayley's hypdeterminant and the principal minors of a symmetric matrix. With an eye towards characterizing the entropy region of jointly Gaussian random variables, we obtain three new results ...
Hassibi, Babak, Shadbakht, Sormeh
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Effect of the number of filaments on the tensile properties of polyacrylonitrile- and pitch-based carbon fiber epoxy-impregnated bundle composites

open access: yesResults in Materials, 2023
This study investigated the effect of the number of filaments on the tensile properties of high tensile strength polyacrylonitrile-based (T1000GB) and high modulus pitch-based (K13D) carbon fiber epoxy-impregnated bundle composites.
Kimiyoshi Naito
doaj   +1 more source

The N=2 supersymmetric unconstrained matrix GNLS hierarchies [PDF]

open access: yes, 2002
The generalization of the N=2 supersymmetric chiral matrix (k|n,m)--GNLS hierarchy (Lett. Math. Phys. 45 (1998) 63, solv-int/9711009) to the case when matrix entries are bosonic and fermionic unconstrained N=2 superfields is proposed.
Kersten, P. H. M., Sorin, A. S.
core   +4 more sources

Amplitude Zeroes in Collinear Processes or What Is Left from a Factorizable 2d Model in Higher Dimensions

open access: yes, 1993
We show that for collinear processes, i.e. processes where the incoming and outgoing momenta are aligned along the same line, the S-matrix of the tree level 2+1 dimensional Thirring model factorizes: any S - matrix element is a product of $2\rightarrow 2$
Aks   +15 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

N=1/2 Global SUSY: R-Matrix Approach

open access: yes, 2012
R-matrix method is used to construct supersymmetric extensions of theta - Euclidean group preserving N = 1/2 supersymmetry and its three- parameter generalization.
Abou-Zeid   +74 more
core   +1 more source

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