Results 21 to 30 of about 171,840 (265)

4-(2-Chloroanilino)-3-phenylfuran-2(5H)-one

Acta Crystallographica Section E, 2011
The title compound, C16H12ClNO2, featuring a furan-2(5H)-one (γ-butyrolactone) core, contains two molecules (A and B) in the asymmetric unit, with different dihedral angles between the central ring and the pendant phenyl and chlorobenzene rings [
Zhu-Ping Xiao, Ze-Jun Huang, Xiao-Yang Liu, Kai-Shuang Xiang, She-Rong Yu   +4 more
doaj   +1 more source

An environmentally benign cascade reaction of 1,2,3-indantriones with ethyl 2-(pyridine-2-yl)acetates for site-selective synthesis of 5H-isochromeno[4,3-b]indolizin-5-ones

Green Synthesis and Catalysis, 2021
A novel approach was developed for the synthesis of 5H-isochromeno [4,3-b]indolizin-5-ones (ICIDOs) 3 through a cascade reaction of 1,2,3-indantriones 1 with ethyl 2-(pyridine-2-yl)acetates 2.
Haodan He, Jiahui Nie, Yinggang Duan, Jun Lin, Shengjiao Yan   +4 more
doaj   +1 more source

Synthesis of 4-alkyl-2(5H)-furanones.

Chemical and Pharmaceutical Bulletin, 1985
An alternative method for the synthesis of 4-alkyl-2 (5H)-furanones is described. Intramolecular carbene addition reaction of α-diazo compounds (4) in the presence of rhodium acetate or copper acetylacetonate furnished the bicyclic compounds (5), which were subjected to cyclopropane ring-opening reaction to give the 4-alkyl-4, 5-dihydrofuran-2 (3H ...
KAMETANI, TETSUJI, KATOH, TADASHI, TSUBUKI, MASAYOSHI, HONDA, TOSHIO   +3 more
openaire   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Evaluating Copper-Doped Biochar Composites for Improving Wheat Nutrition and Growth in Oxisols

Agronomy
Copper (Cu) is a critical micronutrient for wheat (Triticum aestivum L.), essential for growth and grain baking quality, yet its availability is limited because Cu is specifically adsorbed on colloids of highly weathered tropical soils like Oxisols. This
Loren Chisté, Carlos Alberto Silva, Flávio Henrique Silveira Rabêlo, Keiji Jindo, Leônidas Carrijo Azevedo Melo   +4 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Effect of different vase solutions on postharvest longevity of cut foliage Ophiopogon japonicus

Ceylon Journal of Science, 2018
Ophiopogon japonicus (L.f.) Ker-Gawl (family Liliaceae) is an export-oriented foliage plant with attractive white-green strips. The vase life of this cut foliage ends when the leaves loose turgidity and/ or bright green colour.
S. M. K. H. Wijayabandara, J. W. Damunupola, S. A. Krishnarajah, W. A. M. Daundasekera, D. S. A. Wijesundara   +4 more
doaj   +1 more source

Longitudinal Assessment of Biomarkers in ALS: Discriminative Biomarkers for Disease Progression and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the association and discriminative performance of serum biomarkers with clinical disease progression and survival in patients with amyotrophic lateral sclerosis (ALS). Methods This retrospective study, conducted at Houston Methodist Hospital, Houston, TX, used longitudinal serum samples collected between January 2018 and ...
David R. Beers, Yueh‐Yun Lin, Jason R. Thonhoff, Aaron D. Thome, Alireza Faridar, Weihua Zhao, Shixiang Wen, Stanley H. Appel   +7 more
wiley   +1 more source

Anti-anxiety properties of new 5H-2,3-benzodiazepine and 5H-[1,2,5]triazepine derivatives

Research Results in Pharmacology
Introduction: Previous studies have examined the anxiolytic properties of compounds containing mutually annulated systems of 5H-2,3-benzodiazepine and [1,2,4]triazole, namely 7H-[1,2,4]triazolo[3,4-a][2,3]benzodiazepine derivatives.
Maria O. Maltseva, Dmitriy V. Maltsev, Mikhail V. Miroshnikov, Lyudmila N. Divaeva, Anton O. Kharaneko, Oleg I. Kharaneko, Anatolii S. Morkovnik, Alexander A. Spasov   +7 more
doaj   +1 more source

Scientific Opinion on Flavouring Group Evaluation 217 Revision 2 (FGE.217Rev2), consideration of genotoxic potential for α,β‐unsaturated ketones and precursors from chemical subgroup 4.1 of FGE.19: lactones

EFSA Journal, 2019
The Panel on Food Additives and Flavourings of the European Food Safety Authority was requested to evaluate the genotoxic potential of 12 flavouring substances from subgroup 4.1 of FGE.19 in the Flavouring Group Evaluation 217 (FGE.217).
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Karl‐Heinz Engel, Paul Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Peter Moldeus, Agneta Oskarsson, Romina Shah, Ine Waalkens‐Berendsen, Detlef Wölfle, Romualdo Benigni, Claudia Bolognesi, Kevin Chipman, Eugenia Cordelli, Gisela Degen, Daniel Marzin, Camilla Svendsen, Maria Carfì, Giorgia Vianello, Wim Mennes   +25 more
doaj   +1 more source