Results 1 to 10 of about 47,838 (205)

Ionic Liquids in Sustainable Biocatalytic Lactone Synthesis: Green Chemistry Metrics and Process Evaluation [PDF]

Molecules
Ionic liquids remain attractive alternatives as multifunctional media for the sustainable biosynthesis of lactones. Their unique physicochemical properties, including negligible vapor pressure, high thermal stability, and tunable polarity, offer ...
Anna Wolny, Anita Procek, Igor Biały, Izabela Ziębińska, Laura Kudzia, Emilia Gielarowska   +5 more
doaj   +2 more sources

Stereoselective synthesis of whisky lactone isomers catalyzed by bacteria in the genus Rhodococcus

Frontiers in Microbiology, 2023
Whisky lactone is a naturally occurring fragrance compound in oak wood and is widely used as a sensory additive in food products. However, safe and efficient methods for the production of its individual enantiomers for applications in the food industry ...
Dawid Hernik, Francesco Gatti, Elisabetta Brenna, Ewa Szczepańska, Teresa Olejniczak, Filip Boratyński   +5 more
doaj   +1 more source

A PON for All Seasons: Comparing Paraoxonase Enzyme Substrates, Activity and Action including the Role of PON3 in Health and Disease

Antioxidants, 2022
Paraoxonases (PONs) are a family of hydrolytic enzymes consisting of three members, PON1, PON2, and PON3, located on human chromosome 7. Identifying the physiological substrates of these enzymes is necessary for the elucidation of their biological roles ...
Chrysan J. Mohammed, Sabitri Lamichhane, Jacob A. Connolly, Sophia M. Soehnlen, Fatimah K. Khalaf, Deepak Malhotra, Steven T. Haller, Dragan Isailovic, David J. Kennedy   +8 more
doaj   +1 more source

Soil and Vegetation Drive Sesquiterpene Lactone Content and Profile in Arnica montana L. Flower Heads From Apuseni-Mountains, Romania

Frontiers in Plant Science, 2022
Arnica montana L. (AM, Asteraceae) is a perennial, herbaceous vascular plant species of commercial importance. The flower heads’ pharmacological properties are attributed mainly to sesquiterpene lactones (SLs), with phenolic acids and flavonoids also ...
Anja Greinwald, Anja Greinwald, Martin Hartmann, Jörg Heilmann, Michael Heinrich, Rainer Luick, Albert Reif   +6 more
doaj   +1 more source

Methoxy-Substituted γ-Oxa-ε-Lactones Derived from Flavanones—Comparison of Their Anti-Tumor Activity In Vitro

Molecules, 2021
Background: The study investigated four flavanone-derived γ-oxa-ε-lactones: a parent unsubstituted compound and its three derivatives with the methoxy group in positions 2′, 4′ and 8. Our objective was to find out if the introduction of the methoxy group
Aleksandra Pawlak, Marta Henklewska, Beatriz Hernández-Suárez, Monika Siepka, Witold Gładkowski, Czesław Wawrzeńczyk, Karolina Motykiewicz-Pers, Bożena Obmińska-Mrukowicz   +7 more
doaj   +1 more source

Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy

Biomolecules, 2021
Alzheimer’s disease (AD) is a gradually growing irreversible illness of the brain that almost affects every fifth person (aged > 80 years) in the world. World Health Organization (WHO) also revealed that the prevalence of this disease will enhance (upto ...
Ashwani Arya, Rubal Chahal, Rekha Rao, Md. Habibur Rahman, Deepak Kaushik, Muhammad Furqan Akhtar, Ammara Saleem, Shaden M. A. Khalifa, Hesham R. El-Seedi, Mohamed Kamel, Ghadeer M. Albadrani, Mohamed M. Abdel-Daim, Vineet Mittal   +12 more
doaj   +1 more source

Synthesis of Spiroisoxazolines by 1,3-Dipolar Cycloaddition

Molecules, 1997
The cycloaddition of the chiral nitrile oxide 1 to 1-R-substituted 3,3-methylene-5,5-dimethyl-2-pyrrolidinones 2 (where R is H, n-butyl-, 1,1-dimethylethoxycarbonyl-, 1-methylethenyl- and acetyl-) proceeds regioselectively under the formation of ...
Peter Ertl, Vladimír Ondrus, Lubor Fisera, Peter Micuch   +3 more
doaj   +1 more source

Lactones with Methylcyclohexane Systems Obtained by Chemical and Microbiological Methods and Their Antimicrobial Activity

Molecules, 2015
Eight new lactones (δ-chloro-, δ-bromo- and δ-iodo-γ-lactones), each with a methylcyclohexane ring, were obtained by chemical means from (4-methylcyclohex-2-en-1-yl) acetic acid or (6-methylcyclohex-2-en-1-yl) acetic acid.
Małgorzata Grabarczyk, Katarzyna Wińska, Wanda Mączka, Anna K. Żołnierczyk, Barbara Żarowska, Mirosław Anioł   +5 more
doaj   +1 more source

Biotransformation of Bicyclic Halolactones with a Methyl Group in the Cyclohexane Ring into Hydroxylactones and Their Biological Activity

Molecules, 2016
The aim of this study was the chemical synthesis of a series of halo- and unsaturated lactones, as well as their microbial transformation products. Finally some of their biological activities were assessed. Three bicyclic halolactones with a methyl group
Katarzyna Wińska, Małgorzata Grabarczyk, Wanda Mączka, Barbara Żarowska, Gabriela Maciejewska, Katarzyna Dancewicz, Beata Gabryś, Antoni Szumny, Mirosław Anioł   +8 more
doaj   +1 more source

2-Oxo-2H-chromen-3-yl 4-tert-butylbenzoate

IUCrData, 2016
In the title coumarin derivative, C20H18O4, the benzene ring of the benzoate group is oriented at a dihedral angle of 57.55 (9)° with respect to the planar chromene ring system [maximum deviation from plane is 0.027 (2) Å].
Konan René Kambo, Siaka Sosso, Abdoulaye Djandé, Rita Kakou-Yao, Abodou Jules Tenon   +4 more
doaj   +1 more source