Fungal Strains as Catalysts for the Biotransformation of Halolactones by Hydrolytic Dehalogenation with the Dimethylcyclohexane System [PDF]
Molecules, 2012 Bicyclic chloro-, bromo- and iodo-γ-lactones with dimethylcyclohexane rings were used as substrates for bioconversion by several fungal strains (<em>Fusarium</em>, <em>Botrytis</em> and <em>Beauveria</em>). Most of the
Małgorzata Grabarczyk +1 more
exaly +9 more sources
Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil. [PDF]
J Biol Chem, 2020 Cleavage of aromatic carbon-chlorine bonds is critical for the degradation of toxic industrial compounds. Here, we solved the X-ray crystal structure of chlorothalonil dehalogenase (Chd) from Pseudomonas sp. CTN-3, with 15 of its N-terminal residues truncated (ChdT), using single-wavelength anomalous dispersion refined to 1.96 Å resolution. Chd has low
Catlin DS +4 more
europepmc +8 more sources
Microbial Dehalogenation of Synthetic Organohalogen Compounds: Hydrolytic Dehalogenases [PDF]
CHIMIA, 1993 Hydrolytic removal of halogen substitutents is commonly the first step in the degradation of haloaliphatic compounds by aerobic bacteria, whereas initial dehalogenation of aryl halides is rare.
Thomas Leisinger, Regula Bader
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The Operon Encoding Hydrolytic Dehalogenation of 4-Chlorobenzoate Is Transcriptionally Regulated by the TetR-Type Repressor FcbR and Its Ligand 4-Chlorobenzoyl Coenzyme A [PDF]
Applied and Environmental Microbiology, 2021 The bacterial hydrolytic dehalogenation of 4CBA is a special CoA-activation-type catabolic pathway that plays an important role in the biodegradation of polychlorinated biphenyls and some herbicides. With genetic and biochemical approaches, the present study identified the transcriptional repressor and its cognate effector of a 4CBA hydrolytic ...
Xin Yan, Minggen Cheng, Pingping Zhu
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New Hydroxylactones and Chloro-Hydroxylactones Obtained by Biotransformation of Bicyclic Halolactones and Their Antibacterial Activity [PDF]
MoleculesThe aim of this study was to obtain new halolactones with a gem-dimethyl group in the cyclohexane ring (at the C-3 or C-5 carbon) and a methyl group in the lactone ring and then subject them to biotransformations using filamentous fungi.
Małgorzata Grabarczyk +6 more
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Community-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism [PDF]
The Innovation, 2023 Summary: A variety of anthropogenic organohalide contaminants generated from industry are released into the environment and thus cause serious pollution that endangers human health.
Yiqun Huang +8 more
doaj +2 more sources
HadS, a membrane-associated 2-haloacid dehalogenase from the moderate halophile Halobacillus andaensis NEAU-ST10-40T, enhances saline-alkaline tolerance when heterologously expressed in Escherichia coli KNabc [PDF]
Frontiers in MicrobiologyIntroduction2-Haloacid dehalogenases are a subgroup of the haloacid dehalogenase superfamily and catalyze the hydrolytic dehalogenation of 2-haloalkanoic acids.
Li Shao +5 more
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Hydrolytic dehalogenation of the chlorothalonil isomer o-tetrachlorophthalonitrile by Pseudochrobactrum sp. BSQ-1 [PDF]
International Biodeterioration and Biodegradation, 2016 Abstract Microbial dehalogenation plays key roles in the biodegradation and detoxification of halogenated aromatics. Although the hydrolytic dehalogenation of halogenated aliphatic hydrocarbons and carboxylic acids has been extensively studied, there are few reports on the hydrolytic dehalogenation of halogenated aromatics. In this study, the aerobic
Jiandong Jiang, Shunpeng Li
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Identification of genes coding for hydrolytic dehalogenation in the metagenome derived from a denitrifying 4-chlorobenzoate degrading consortium [PDF]
FEMS Microbiology Letters, 2008 A metagenomic approach was taken to investigate the genetic basis for the ability of an anaerobic consortium to grow on either 4-chlorobenzoate or 4-bromobenzoate under denitrifying conditions. Degenerate PCR primers were designed for the family of 4-chlorobenzoyl-CoA dehalogenase genes.
Gerben Zylstra, Song Bongkeun
exaly +3 more sources
Macroalgal microbiomes unveil a valuable genetic resource for halogen metabolism [PDF]
MicrobiomeBackground Macroalgae, especially reds (Rhodophyta Division) and browns (Phaeophyta Division), are known for producing various halogenated compounds. Yet, the reasons underlying their production and the fate of these metabolites remain largely unknown ...
Anna Lavecchia +7 more
doaj +2 more sources