Fungal Strains as Catalysts for the Biotransformation of Halolactones by Hydrolytic Dehalogenation with the Dimethylcyclohexane System [PDF]
Molecules, 2012 Bicyclic chloro-, bromo- and iodo-γ-lactones with dimethylcyclohexane rings were used as substrates for bioconversion by several fungal strains (<em>Fusarium</em>, <em>Botrytis</em> and <em>Beauveria</em>). Most of the
Małgorzata Grabarczyk
exaly +8 more sources
Structural basis for the hydrolytic dehalogenation of the fungicide chlorothalonil. [PDF]
J Biol Chem, 2020 Cleavage of aromatic carbon-chlorine bonds is critical for the degradation of toxic industrial compounds. Here, we solved the X-ray crystal structure of chlorothalonil dehalogenase (Chd) from Pseudomonas sp. CTN-3, with 15 of its N-terminal residues truncated (ChdT), using single-wavelength anomalous dispersion refined to 1.96 Å resolution. Chd has low
Catlin DS +4 more
europepmc +7 more sources
Microbial Dehalogenation of Synthetic Organohalogen Compounds: Hydrolytic Dehalogenases [PDF]
CHIMIA, 1993 Hydrolytic removal of halogen substitutents is commonly the first step in the degradation of haloaliphatic compounds by aerobic bacteria, whereas initial dehalogenation of aryl halides is rare.
Thomas Leisinger, Regula Bader
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The Operon Encoding Hydrolytic Dehalogenation of 4-Chlorobenzoate Is Transcriptionally Regulated by the TetR-Type Repressor FcbR and Its Ligand 4-Chlorobenzoyl Coenzyme A [PDF]
Applied and Environmental Microbiology, 2021 The bacterial hydrolytic dehalogenation of 4CBA is a special CoA-activation-type catabolic pathway that plays an important role in the biodegradation of polychlorinated biphenyls and some herbicides. With genetic and biochemical approaches, the present study identified the transcriptional repressor and its cognate effector of a 4CBA hydrolytic ...
Xin Yan, Minggen Cheng
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Community-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism [PDF]
The Innovation, 2023 Summary: A variety of anthropogenic organohalide contaminants generated from industry are released into the environment and thus cause serious pollution that endangers human health.
Yiqun Huang +8 more
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HadS, a membrane-associated 2-haloacid dehalogenase from the moderate halophile Halobacillus andaensis NEAU-ST10-40T, enhances saline-alkaline tolerance when heterologously expressed in Escherichia coli KNabc [PDF]
Frontiers in MicrobiologyIntroduction2-Haloacid dehalogenases are a subgroup of the haloacid dehalogenase superfamily and catalyze the hydrolytic dehalogenation of 2-haloalkanoic acids.
Li Shao +5 more
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Hydrolytic dehalogenation of the chlorothalonil isomer o-tetrachlorophthalonitrile by Pseudochrobactrum sp. BSQ-1 [PDF]
International Biodeterioration and Biodegradation, 2016 Abstract Microbial dehalogenation plays key roles in the biodegradation and detoxification of halogenated aromatics. Although the hydrolytic dehalogenation of halogenated aliphatic hydrocarbons and carboxylic acids has been extensively studied, there are few reports on the hydrolytic dehalogenation of halogenated aromatics. In this study, the aerobic
Junhua Wang +2 more
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Identification of genes coding for hydrolytic dehalogenation in the metagenome derived from a denitrifying 4-chlorobenzoate degrading consortium [PDF]
FEMS Microbiology Letters, 2008 A metagenomic approach was taken to investigate the genetic basis for the ability of an anaerobic consortium to grow on either 4-chlorobenzoate or 4-bromobenzoate under denitrifying conditions. Degenerate PCR primers were designed for the family of 4-chlorobenzoyl-CoA dehalogenase genes.
Jong-Chan Chae, Gerben Zylstra
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New Hydroxylactones and Chloro-Hydroxylactones Obtained by Biotransformation of Bicyclic Halolactones and Their Antibacterial Activity [PDF]
MoleculesThe aim of this study was to obtain new halolactones with a gem-dimethyl group in the cyclohexane ring (at the C-3 or C-5 carbon) and a methyl group in the lactone ring and then subject them to biotransformations using filamentous fungi.
Małgorzata Grabarczyk +6 more
doaj +2 more sources
Reductive dechlorination of 2,4-dichlorobenzoate to 4-chlorobenzoate and hydrolytic dehalogenation of 4-chloro-, 4-bromo-, and 4-iodobenzoate by Alcaligenes denitrificans NTB-1 [PDF]
Applied and Environmental Microbiology, 1987 Alcaligenes denitrificans NTB-1, previously isolated on 4-chlorobenzoate, also utilized 4-bromo-, 4-iodo-, and 2,4-dichlorobenzoate but not 4-fluorobenzoate as a sole carbon and energy source. During growth, stoichiometric amounts of halide were released.
J A de Bont
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