Identification of Pyrazolidine-3-One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors. [PDF]
ChemMedChemFollowing the discovery of oxadiazin‐5‐ones as partial inhibitors of the ATP synthase, we herein report the synthesis of a library of pyrazolidine‐3‐ones and pyrazol‐3‐ones, designed by reducing the six‐membered N–N heterocycles to five‐membered rings.
Reichert L +8 more
europepmc +2 more sources
Continuous Spectrophotometric Assay for Defluorinase and Dechlorinase Activities With α-Halocarboxylic Acids. [PDF]
Microb BiotechnolMicrobial hydrolytic defluorinases and dechlorinases assayed by coupling the reaction product to NAD‐linked dehydrogenases will facilitate screening for and characterising new and known enzymes. ABSTRACT Many environmental pollutants have a fluorine or chlorine atom on a carbon atom adjacent to a carboxylic acid.
Ronnander M +6 more
europepmc +2 more sources
, 2019 Organohalides are routinely detected in fluid produced from hydraulically fractured oil and natural-gas wells, yet the origin and fate of these compounds remain largely unknown.
Kelly C. Wrighton (280140) +6 more
core +4 more sources
Nonconventional hydrolytic dehalogenation of 1-chlorobutane by dehydrated bacteria in a continuous solid-gas biofilter [PDF]
, 2005 Rhodococcus erythropolis NCIMB 13064 and Xanthobacter autotrophicus GJ10 are able to catalyze the conversion of halogenated hydrocarbons to their corresponding alcohols.
Seltana, Amira +5 more
core +1 more source
Combination of a UPO-Based Epoxidation With a Subsequent Ring-Opening Reaction for the Synthesis of Amino Alcohols. [PDF]
ChembiochemThe synthesis of aromatic amino alcohols via a combination of an unspecific peroxygenase‐catalysed reaction, oxyfunctionalization, and addition of selected nucleophiles and electrophiles in a highly atom‐efficient manner was investigated. This study presents the design to aim for an atom‐efficient chemo‐enzymatic synthesis route towards aromatic amino ...
Last S +3 more
europepmc +2 more sources
, 2022 As a typical brominated flame retardants (BFRs), 2,4,6-tribromophenol (TBP) has serious hazard to the environmental health and its environmental fate has attracted considerable attention.
Hu, Xiaoke +6 more
core +1 more source
Regio- and Enantioselective Sequential Dehalogenation of rac-1,3-Dibromobutane by Haloalkane Dehalogenase LinB [PDF]
, 2016 The hydrolytic dehalogenation of rac-1,3-dibromobutane catalyzed by the haloalkane dehalogenase LinB from Sphingobium japonicum UT26 proceeds in a sequential fashion: initial formation of intermediate haloalcohols followed by a second hydrolytic step to ...
Zbyněk Prokop +9 more
core +1 more source
Biotransformation of Lactones with Methylcyclohexane Ring and Their Biological Activity
Applied Sciences, 2016 The aim of the study was to obtain biological active compounds during biotransformation. Three bicyclic halolactones with methylcyclohexane ring (2-chloro-4-methyl-9-oxabicyclo-[4.3.0]nonan-8-one, 2-bromo-4-methyl-9-oxabicyclo[4.3.0]nona- -8-one and 2 ...
Katarzyna Wińska +7 more
doaj +1 more source
Molecules, 2015 Eight new lactones (δ-chloro-, δ-bromo- and δ-iodo-γ-lactones), each with a methylcyclohexane ring, were obtained by chemical means from (4-methylcyclohex-2-en-1-yl) acetic acid or (6-methylcyclohex-2-en-1-yl) acetic acid.
Małgorzata Grabarczyk +5 more
doaj +1 more source
Bioremediation of halogenated compounds: comparison of dehalogenating bacteria and improvement of catalyst stability [PDF]
, 2006 Five bacterial strains were compared for halogenated compounds conversion in aqueous media. Depending on the strain, the optimal temperature for dehalogenase activity of resting cells varied from 30 to 45 degrees C, while optimal pH raised from 8.4 to 9 ...
Legoy, Marie-Dominique +5 more
core +1 more source