Antiproliferative and Structure Activity Relationships of Amaryllidaceae Alkaloids [PDF]
Molecules, 2015 The antiproliferative activity of a set of seven natural Amaryllidaceae alkaloids and 32 derivatives against four cancer cell lines (A2780, SW1573, T47-D and WiDr) was determined.
Juan C. Cedrón +4 more
doaj +8 more sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018 In our present research, we synthesised new thiazolidine-2,4-diones (12–28). All the newly synthesised compounds were evaluated for antiproliferative and antibacterial activity.
Nazar Trotsko +5 more
doaj +3 more sources
Design, Synthesis and Evaluation of Antiproliferative Activity of New Benzimidazolehydrazones [PDF]
Molecules, 2016 The synthesis and antiproliferative activity of new benzimidazole derivatives bearing an hydrazone mojety at the 2-position is described. The new N′-(4-arylidene)-1H-benzo[d]imidazole-2-carbohydrazides were evaluated for their cytostatic activity toward ...
Valentina Onnis +8 more
doaj +4 more sources
Antiproliferative activity of spinasterol isolated of Stegnosperma halimifolium (Benth, 1844)
Saudi Pharmaceutical Journal, 2017 Cancer is the major cause of death in the world, representing a significant public health problem. Plants have been shown as a great source of secondary metabolites with anticancer activity.
Salvador Enrique Meneses-Sagrero +5 more
doaj +2 more sources
Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity
Molecules, 2019 Oligonucleotides with an antiproliferative activity for human cancer cells have attracted attention over the past decades; many of them have a G-quadruplex structure (GQ), and a cryptic target.
Olga Antipova +6 more
doaj +2 more sources
Multitarget Antiproliferative Activity of Pituranthos scoparius: An Integrated Phytochemical, Biological and Computational Insights into Key Oncogenic Pathways [PDF]
MoleculesBackground: Pituranthos scoparius (Apiaceae), commonly known in Algeria as “Kozah”, is a medicinal plant traditionally used for various therapeutic purposes.
Sarra Chabane +8 more
doaj +2 more sources
Biological Activity Survey of Pereskia aculeata Mill. and Pereskia grandifolia Haw. (Cactaceae) [PDF]
Pharmaceutical Sciences, 2022 Background: Pereskia aculeata and P. grandifolia are non-traditional Brazilian vegetables with high nutritional value used in traditional medicine.
Adriana Muniz Massocatto +7 more
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The cancer preventive activity and mechanisms of prenylated resveratrol and derivatives
Current Research in Toxicology, 2023 Resveratrol is regarded as neutraceuticals with multiple health benefits. The introduction of prenyl can enhance the bioactivity. In this work, the cancer preventive activities and mechanisms of 18 prenylated reseveratrol and derivatives were ...
Ting Zhou +3 more
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Antiproliferative and apoptosis-inducing properties of selected medicinal plants of Assam, India
Archives of Medicine and Health Sciences, 2021 Background and Aim: Ethnomedicine is a common practice of disease treatment among tribal communities of India. The present study investigated the antiproliferative and apoptosis-inducing activities of seven medicinal plants traditionally used by the Bodo
Mritunjoy Kumar Roy +2 more
doaj +1 more source
Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. [PDF]
PLoS ONE, 2016 In our continuing structure-activity relationship study of a new class of erythromycin A (EM-A) derivatives with antiproliferative activity, a new series of de(N-methyl) EM-A dimers jointed by a four-atom linker, -CH2CH = CHCH2-, were prepared and their ...
Lan Wu +7 more
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