Results 31 to 40 of about 98,614 (298)

Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit

open access: yesMolecules, 2022
The fruit of Tetradium ruticarpum (TR) is commonly used in Chinese herbal medicine and it has known antiproliferative and antitumor activities, which can serve as a good source of functional ingredients.
Chun-Han Su   +9 more
doaj   +1 more source

Antiproliferative Activity of Greek Propolis

open access: yesJournal of Medicinal Food, 2010
The butanolic extract and the isolated chemical constituents, mainly diterpenes and flavonoids, from Greek propolis have been tested for their cytostatic activities against human malignant and normal cell strains. The extract and the diterpenes were found to be the most active against HT-29 human colon adenocarcinoma cells, without affecting normal ...
Pratsinis, H.   +3 more
openaire   +3 more sources

Synthesis and Antiproliferative Activities of Ottelione A Analogues [PDF]

open access: yesACS Medicinal Chemistry Letters, 2012
Through the syntheses of its C-1 desvinyl, C-7 methylene, C-7 exocyclic ethylidene, and various C-3 phenylmethyl analogues, the structure-activity relationship of antimitotic ottelione A (4) against tubulin and various cancer cells was established. The results indicated that compound 4 was a colchicine-competitive inhibitor and that the C-1 vinyl group
Tsai-Yuan, Chang   +7 more
openaire   +2 more sources

Characterization of Nanoparticles Containing Achillea Phrygia and Their Antioxidant and Antiproliferative Properties

open access: yesCumhuriyet Science Journal, 2022
In this study, antioxidant and antiproliferative properties of ‘‘Achillea phrygia’’ were investigated. Since the antioxidant and antiproliferative activity of B sub-extract from plant’s chloroform extract is higher than other extracts, B sub-extract of ...
Murat Doğan   +3 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of a New Series of 1-Aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea Derivatives as Antiproliferative Agents

open access: yesMolecules, 2019
To discover new antiproliferative agents with high efficacy and selectivity, a new series of 1-aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea derivatives (7a–7t) were designed, synthesized and evaluated for their antiproliferative activity against A549,
Chuanming Zhang   +8 more
doaj   +1 more source

Antiproliferative and Trypanocidal Activity of Ivermectin Bioconjugates [PDF]

open access: yesACS Omega
Ivermectin (IVR), whose discovery has been Nobel-Prize-honored, is a 16-membered macrocyclic lactone used in medicine as an extremely effective and safe antiparasitic drug. In recent years, interest in this compound has grown due to its potential effectiveness in killing various types of cancer cells. However, research on the anticancer activity of IVR
Michał Sulik   +4 more
openaire   +3 more sources

The contribution of different polyphenol compositions from chokeberry produced in China to cellular antioxidant and antiproliferative activities

open access: yesFood Science and Human Wellness, 2023
Abundant polyphenols make chokeberry have beneficial antioxidant and antiproliferative activity. In order to explore the contribution of different polyphenols in chokeberry to these activities, this study was conducted to determine polyphenol composition
Ningxuan Gao   +9 more
doaj   +1 more source

Antioxidant and antiproliferative activity of Asparagopsis Taxiformis

open access: yesPharmacognosy Research, 2017
Asparagopsis taxiformis (Rhodophyta) is a species of red algae belonging to the family Bonnemaisoniaceae. The objective of the present study was to evaluate antioxidant and antiproliferative activity of four fractions (petroleum ether, chloroform, ethyl acetate, and methanol) of A. taxiformis.The red seaweed, A.
Neethu, P. V.   +2 more
openaire   +3 more sources

Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity

open access: yes, 2022
Although various dual-target tubulin inhibitors have been designed and synthesised, no dual tubulin-NEDDylation inhibitors as antiproliferative agents were reported so far.
Fu, Dong-Jun   +3 more
core   +2 more sources

Gallic Acid Content and an Antioxidant Mechanism Are Responsible for the Antiproliferative Activity of ‘Ataulfo’ Mango Peel on LS180 Cells

open access: yesMolecules, 2018
Mango “Ataulfo” peel is a rich source of polyphenols (PP), with antioxidant and anti-cancer properties; however, it is unknown whether such antiproliferative activity is related to PP’s antioxidant activity.
Gustavo. R. Velderrain-Rodríguez   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy