Results 1 to 10 of about 1,162,957 (316)

Establishment and identification of human placental site trophoblastic tumor cell line

open access: yesZhongguo aizheng zazhi, 2017
Background and purpose: Placental site trophoblastic tumor (PSTT) is a special type of gestational trophoblastic tumor. It remains no general cell line for PSTT. The aim of this study was to establish and identify a human PSTT cell line. Methods: In this
刘齐雨, 李 可, 胥 婧
doaj  

Molecular Modes of Action of Artesunate in Tumor Cell Lines

open access: yesMolecular Pharmacology, 2003
A profound cytotoxic action of the antimalarial, artesunate (ART), was identified against 55 cancer cell lines of the U.S. National Cancer Institute (NCI). The 50% inhibition concentrations (IC50 values) for ART correlated significantly to the cell doubling times (P = 0.00132) and the portion of cells in the G0/G1 (P = 0.02244) or S cell cycle phases ...
Efferth, T.   +11 more
openaire   +3 more sources

Bioguided fractionation from Solanum elaeagnifolium to evaluate toxicity on cellular lines and breast tumor explants

open access: yesVitae, 2017
Background: Bioactive compounds were isolated from the fruit of S. elaeagnifolium, as it has a high potential for functional foods or pharmaceutical products development.
Leobardo HERNÁNDEZ O.   +5 more
doaj  

A Logarithmic Formula to Describe the Relationship between the Increased Radiosensitivity at Low Doses and the Survival at 2 Gray

open access: yesSultan Qaboos University Medical Journal, 2013
Objectives: Intrinsic radiosensitivity at doses used in radiotherapy is linked to hypersensitivity (HRS) and increased radio resistance (IRR) at low doses. The aim of this study was to explore this relationship.
Faika A. Azooz, Suzan K. Hash
doaj  

A Double‐Humanized Murine Model in Bladder Cancer: A Novel Preclinical Model for Cancer Immunology Research

open access: yesCancer Medicine
Background Bladder cancer (BC) ranks as the 10th leading cause of cancer‐related deaths in the United States. Despite significant advancements in managing BC, including antibody‐drug conjugates and immune checkpoint blockers, a significant percentage of ...
Niannian Ji   +7 more
doaj   +1 more source

Multiple Myeloma Cells Express Key Immunoregulatory Cytokines and Modulate the Monocyte Migratory Response

open access: yesFrontiers in Medicine, 2017
Multiple myeloma (MM) is a plasma cell disorder that still remains incurable. The immune dysfunction of the host is a striking characteristic of MM, leading to tumor growth and reducing the survival rate of patients.
Leonardo Freire-de-Lima   +9 more
doaj   +1 more source

OT17 a novel microsatellite stable colorectal cancer cell line and organoid model for investigating BRAF V600E mutant tumorigenesis and targeted therapeutics

open access: yesBiochemistry and Biophysics Reports
Human cancer cell lines serve as essential in vitro models for investigating tumor biology, carcinogenesis, molecular genetics, metastasis, and tumor evolution. In this study, we establish and characterize the OT17 cell line, derived from a moderately to
Chen Zheng   +11 more
doaj   +1 more source

Establishment and Characterization of MCA23, a Novel Mouse Intrahepatic Cholangiocarcinoma Cell Line

open access: yesCancer Medicine
Introduction Intrahepatic cholangiocarcinoma (ICC) is an aggressive type of malignancy. Recent advancements have highlighted the importance of the tumor immune microenvironment in therapeutic responses and prognosis.
Yuchao He   +12 more
doaj   +1 more source

Preliminary study of the relationship between aneuploidy and tumorigenicity of tumor cells

open access: yesZhongguo aizheng zazhi, 2017
Background and purpose: Aneuploidy is associated with tumor formation. This study aimed to study the relationship between aneuploidy and tumorigenicity of tumor cells.
康燕燕, 徐 阳
doaj  

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