Results 21 to 30 of about 1,118,590 (267)
Storage conditions and passages alter IL-6 secretion in C26 adenocarcinoma cell lines
MethodsX, 2015 The C26 adenocarcinoma tumor line is frequently used to establish peripheral tumors in mice for the study of cancer cachexia and cancer-related fatigue. Recently, we have noticed a progressive decline in the effects of tumor growth on our biological and ...
Diana M. Norden +3 more
doaj +1 more source
Biomedicines, 2022 The host defense derived peptide was assessed in different model systems with increasing complexity employing the highly aggressive NRAS mutated melanoma metastases cell line MUG-Mel2.
Maximiliane Wußmann +9 more
doaj +1 more source
The Role of Cell Lines in the Study of Neuroendocrine Tumors [PDF]
Neuroendocrinology, 2012 Cell lines originating from neuroendocrine tumors (NETs) represent useful experimental models to assess the control of synthesis and release of different hormones and hormone-like peptides, to evaluate the mechanisms of action of these agents in target tissues at the cellular and subcellular levels, and to study cell proliferation and tumor development,
Simona, Grozinsky-Glasberg +2 more
openaire +2 more sources
Nanomaterials, 2023 Multidrug resistance (MDR) is the main challenge in cancer treatment. In this sense, we designed transferrin (Tf)-conjugated PLGA nanoparticles (NPs) containing an organoselenium compound as an alternative to enhance the efficacy of cancer therapy and ...
Letícia Bueno Macedo +8 more
doaj +1 more source
Generation of Luciferase-expressing Tumor Cell Lines
BIO-PROTOCOL, 2018 Murine tumor models have been critical to advances in our knowledge of tumor physiology and for the development of effective tumor therapies. Essential to these studies is the ability to both track tumor development and quantify tumor burden in vivo. For this purpose, the introduction of genes that confer tumors with bioluminescent properties has been ...
Todd Brennan +3 more
openaire +4 more sources
Establishment of a Novel IDH1 wild type Glioblastoma Cell Line, SHG142, and Its Organoids
Frontiers in Bioscience-LandmarkBackground: Glioblastoma (GBM) is the most aggressive primary malignant brain tumor and is associated with limited treatment options and poor prognosis.
Heyang Gao +8 more
doaj +1 more source
Experimental Adaptation of Rotaviruses to Tumor Cell Lines
PLOS ONE, 2016 A number of viruses show a naturally extended tropism for tumor cells whereas other viruses have been genetically modified or adapted to infect tumor cells. Oncolytic viruses have become a promising tool for treating some cancers by inducing cell lysis or immune response to tumor cells. In the present work, rotavirus strains TRF-41 (G5) (porcine), RRV (
Carlos A Guerrero +4 more
openaire +4 more sources
Ablative and Immunostimulatory Effects of Histotripsy Ablation in a Murine Osteosarcoma Model
Biomedicines, 2023 Background: Osteosarcoma (OS) is the most frequently occurring malignant bone tumor in humans, primarily affecting children and adolescents. Significant advancements in treatment options for OS have not occurred in the last several decades, and the ...
Alayna N. Hay +10 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Cancer Medicine, 2020 Basic and clinical studies on small bowel adenocarcinoma (SBA) are limited due to the rare nature of this cancer. We established a patient‐derived xenograft (PDX) model from the tumor tissue of an advanced SBA patient with liver and peritoneal metastasis,
Tomoki Yamano +2 more
doaj +1 more source