Results 41 to 50 of about 10,955,102 (315)

Ablative and Immunostimulatory Effects of Histotripsy Ablation in a Murine Osteosarcoma Model

Biomedicines, 2023
Background: Osteosarcoma (OS) is the most frequently occurring malignant bone tumor in humans, primarily affecting children and adolescents. Significant advancements in treatment options for OS have not occurred in the last several decades, and the ...
Alayna N. Hay, Khan Mohammad Imran, Alissa Hendricks-Wenger, Jessica M. Gannon, Jacqueline Sereno, Alex Simon, Victor A. Lopez, Sheryl Coutermarsh-Ott, Eli Vlaisavljevich, Irving C. Allen, Joanne L. Tuohy   +10 more
doaj   +1 more source

3d Cell-selex: Development Of Rna Aptamers As Molecular Probes For Pc-3 Tumor Cell Line

, 2016
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Human prostate cancer (PCa) is a highly heterogeneous and multifactorial disease.
VAF; Goulart, Souza, K; Fujimura, PT; Alves, LR; Goulart, PT; Silva, VA, AG; Marangoni, MJ; Bastos   +8 more
core   +2 more sources

A patient‐derived xenograft and a cell line derived from it form a useful preclinical model for small bowel adenocarcinoma

Cancer Medicine, 2020
Basic and clinical studies on small bowel adenocarcinoma (SBA) are limited due to the rare nature of this cancer. We established a patient‐derived xenograft (PDX) model from the tumor tissue of an advanced SBA patient with liver and peritoneal metastasis,
Tomoki Yamano, Shuji Kubo, Naohiro Tomita   +2 more
doaj   +1 more source

Establishment and characterization of a HER2-enriched canine mammary cancerous myoepithelial cell line

BMC Veterinary Research, 2023
Background Canine mammary tumors (CMTs) have a poor prognosis, along with tumor recurrence and metastasis. Cell lines are vital in vitro models for CMT research. Many CMT epithelial cell lines were reported.
Aolei Chen, Shaotang Ye, Jiahui Zheng, Jichao Li, Zejia Chen, Yashan Zhang, Shoujun Li   +6 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Mechanisms of Rejection of High Grade B cell Lymphoma in Mice [PDF]

, 2008
The incidence of high grade B cell lymphoma in western countries has increased over the last decades. Improvement of conventional chemotherapy regimens has significantly contributed to prolonged 5-year survival rates which currently reach around 60 ...
Sukumar, Madhusudhanan
core   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Myoblasts inhibit prostate cancer growth by paracrine secretion of TNF alpha [PDF]

, 2013
PURPOSE: Myoblasts are capable of forming muscle fibers after transplantation and are therefore envisioned as a treatment for urinary incontinence after radical prostatectomy.
Handschin, Christoph, Sulser, Tullio, Eberli, Daniel, Stölting, Meline Nogueira Lucena, Provenzano, Maurizio; https://orcid.org/, Ferrari, Stefano, Becskei, Attila, Stölting, Meline N L, Provenzano, Maurizio, Sulser T, Ferrari S, Becskei A, Eberli D, Stölting MN, Handschin C, Provenzano M   +15 more
core   +1 more source

Development of a Transplantable GFP+ B-Cell Lymphoma Tumor Cell Line From MHC-Defined Miniature Swine: Potential for a Large Animal Tumor Model

Frontiers in Oncology, 2019
The lack of a reliable and reproducible large animal tumor model for the study of hemolymphatic malignancies limits the ability to explore the underlying pathophysiology and testing of novel therapies. The goal of this study was to develop an aggressive,
Marian Schenk, Abraham J. Matar, Abraham J. Matar, Isabel Hanekamp, Robert J. Hawley, Christene A. Huang, Christene A. Huang, Raimon Duran-Struuck, Raimon Duran-Struuck   +8 more
doaj   +1 more source

Phenotype of polyoma-induced hamster tumor cells lines [PDF]

Journal of Virology, 1980
Cell lines from polyoma-induced hamster tumors exhibit a fully transformed phenotype despite the absence of the 105K (105,000-dalton) form of polyoma T-antigen.
M A, Israel, M A, Martin, T, Miyamura, K K, Takemoto, D, Rifkin, R, Pollack   +5 more
openaire   +2 more sources