Results 1 to 10 of about 7,903,122 (310)

The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond

Cell Division, 2008
During mitosis, correct bipolar chromosome attachment to the mitotic spindle is an essential prerequisite for the equal segregation of chromosomes. The spindle assembly checkpoint can prevent chromosome segregation as long as not all chromosome pairs ...
Maia André F, Vader Gerben, Lens Susanne MA   +2 more
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CIP/KIP and INK4 families as hostages of oncogenic signaling

Cell Division
CIP/KIP and INK4 families of Cyclin-dependent kinase inhibitors (CKIs) are well-established cell cycle regulatory proteins whose canonical function is binding to Cyclin-CDK complexes and altering their function.
Lucia Csergeová, David Krbušek, Radoslav Janoštiak   +2 more
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The many faces of ubiquitinated histone H2A: insights from the DUBs

Cell Division, 2008
Monoubiquitination of H2A is a major histone modification in mammalian cells. Understanding how monoubiquitinated H2A (uH2A) regulates DNA-based processes in the context of chromatin is a challenging question.
Di Fiore Pier, van Lohuizen Maarten, Nicassio Francesco, Vissers Joseph HA, Citterio Elisabetta   +4 more
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GSK3 regulates the expressions of human and mouse c-Myb via different mechanisms

Cell Division, 2010
Background c-Myb is expressed at high levels in immature progenitors of all the hematopoietic lineages. It is associated with the regulation of proliferation, differentiation and survival of erythroid, myeloid and lymphoid cells, but decreases during the
Suzuki Sayuri, Liu Ning, Hiramatsu Yoshihiro, Kotake Yojiro, Kitagawa Kyoko, Nakamura Satoki, Kikuchi Akira, Kitagawa Masatoshi   +7 more
doaj   +1 more source

Emerging roles of the SUMO pathway in mitosis

Cell Division, 2008
SUMO proteins are small ubiquitin-like modifiers found in all eukaryotes that become covalently conjugated to other cellular proteins. The SUMO conjugation pathway is biochemically similar to ubiquitin conjugation, although the enzymes within the pathway
Dasso Mary
doaj   +1 more source

APC/C – the master controller of origin licensing?

Cell Division, 2007
DNA replication must be tightly controlled to prevent initiation of a second round of replication until mitosis is complete. So far, components of the pre-replicative complex (Cdt1, Cdc6 and geminin) were considered key players in this regulation.
Dutta Anindya, Machida Yuichi J, Sivaprasad Umasundari   +2 more
doaj   +1 more source

Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, guieranone A

Cell Division, 2012
Background Malignant diseases are responsible of approximately 13% of all deaths each year in the world. Natural products represent a valuable source for the development of novel anticancer drugs.
Kuete Victor, Eichhorn Tolga, Wiench Benjamin, Krusche Benjamin, Efferth Thomas   +4 more
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Characterization of the antiproliferative activity of Xylopia aethiopica

Cell Division, 2012
Background Xylopia aethiopica, a plant found throughout West Africa, has both nutritional and medicinal uses. The present study aims to characterize the effects of extracts of this plant on cancer cells. Results We report that X.
Choumessi Aphrodite T, Danel Mathieu, Chassaing Stefan, Truchet Isabelle, Penlap Véronique B, Pieme Anatole, Asonganyi Tazoacha, Ducommun Bernard, Valette Annie   +8 more
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TFAP2A upregulates FAM83A to suppress ferroptosis and diminish cisplatin sensitivity in non-small cell lung cancer

Cell Division
Background FAM83A plays a significant role in the development of non-small cell lung cancer (NSCLC). This study elucidated the biological role of FAM83A in ferroptosis and cisplatin (DDP) sensitivity in NSCLC cells.
Qi Sun, Weifeng Qu, Ye Wang, Kejia Yang, Yuan Weng   +4 more
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Detection of early relapse in multiple myeloma patients

Cell Division
Background Multiple myeloma (MM) represents the second most common hematological malignancy characterized by the infiltration of the bone marrow by plasma cells that produce monoclonal immunoglobulin.
Tereza Růžičková, Monika Vlachová, Lukáš Pečinka, Monika Brychtová, Marek Večeřa, Lenka Radová, Simona Ševčíková, Marie Jarošová, Josef Havel, Luděk Pour, Sabina Ševčíková   +10 more
doaj   +1 more source