Results 31 to 40 of about 7,478,668 (259)
Genetic requirements for cell division in a genomically minimal cell
Genomically minimal cells, such as JCVI-syn3.0, offer a platform to clarify genes underlying core physiological processes. Although this minimal cell includes genes essential for population growth, the physiology of its single cells remained ...
Ellisman, Mark H +11 more
core +1 more source
Genetic Control of Plant Development by Overriding a Geometric Division Rule [PDF]
Formative cell divisions are critical for multicellular patterning. In the early plant embryo, such divisions follow from orienting the division plane.
Barbier de Reuille, Pierre +6 more
core +3 more sources
CLK3 promotes tumor proliferation by activating MYC signaling
Colorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide, posing a significant public health challenge. Despite advancements in treatment strategies, prognosis for advanced CRC remains poor.
Jing Shen, Yu Zhao, Yang Man, Xuling Sun
doaj +1 more source
Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis
Haematopoietic cell number is maintained by a delicate balance between cell proliferation, differentiation and death. Gene knockout studies in mice have revealed the complex roles of cyclins, CDKs, and CDK inhibitors in regulating cell proliferation and ...
Lam Eric, Myatt Stephen S
doaj +1 more source
MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora +7 more
doaj +1 more source
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Background Overexpression or downregulation of long noncoding RNA (lncRNA) plays an essential role in the progression and chemotherapy-resistant of breast cancer (BRCA). LncPRESS1 is a lncRNA regulated by p53, suggesting its potential in participating in
Longzhu Ke +7 more
doaj +1 more source
Measuring DNA content in live cells by fluorescence microscopy
Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associated ...
Cecil J. Gomes +4 more
doaj +1 more source
Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan +18 more
wiley +1 more source
Molecular pathology of microRNA-339 during tumor progression
Cancer, as one of the main causes of human deaths, has an adverse effect on the quality of life in cancer patients. Despite many advances in diagnostic and therapeutic methods, there is still a poor prognosis in cancer patients that can be associated ...
Iman Akhlaghipour +2 more
doaj +1 more source

