Merotelic attachments and non-homologous end joining are the basis of chromosomal instability
Cell Division, 2010 Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis.
van Wely Karel HM +2 more
doaj +1 more source
FtsZ of filamentous, heterocyst-forming cyanobacteria has a conserved N-Terminal peptide required for normal FtsZ polymerization and cell division [PDF]
, 2018 Filamentous cyanobacteria grow by intercalary cell division, which should involve distinct steps compared to those producing separate daughter cells. The N-terminal region of FtsZ is highly conserved in the clade of filamentous cyanobacteria capable of ...
Camargo Bernal, Sergio +6 more
core +4 more sources
The mechanics of microtubule networks in cell division
Journal of Cell Biology, 2017 The primary goal of a dividing somatic cell is to accurately and equally segregate its genome into two new daughter cells. In eukaryotes, this process is performed by a self-organized structure called the mitotic spindle.
Scott Forth, T. Kapoor
semanticscholar +1 more source
Influence of cell cycle phase on calcification in the coccolithophore Emiliania huxleyi [PDF]
, 2008 Calcification of the cosmopolitan coccolithophore species Emiliania huxleyi was investigated in relation to the cell division cycle with the use of batch cultures.
Antia, Avan +2 more
core +1 more source
p27kip1 at the crossroad between actin and microtubule dynamics
Cell Division, 2019 The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra +5 more
doaj +1 more source
Physiological and transcriptomic evidence for a close coupling between chloroplast ontogeny and cell cycle progression in the pennate diatom Seminavis robusta [PDF]
, 2008 Despite the growing interest in diatom genomics, detailed time series of gene expression in relation to key cellular processes are still lacking. Here, we investigated the relationships between the cell cycle and chloroplast development in the pennate ...
Chepurnov, Victor A +12 more
core +3 more sources
Cell Division, 2019 The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases.
Shivangee Bansal, Swati Tiwari
doaj +1 more source
JAB1/CSN5: a new player in cell cycle control and cancer
Cell Division, 2010 c-Jun activation domain-binding protein-1 (Jab1) acts as a modulator of intracellular signaling and affects cellular proliferation and apoptosis, through its existence as a monomer or as the fifth component of the constitutive photomorphogenic-9 ...
Claret Francois X, Shackleford Terry J
doaj +1 more source
Expression of genes regulating cell division in porcine follicular granulosa cells
Cell Division, 2023 Background Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many diseases within the ovary.
Jakub Kulus +7 more
doaj +1 more source
Aging and Immortality in a Cell Proliferation Model
, 2008 We investigate a model of cell division in which the length of telomeres within the cell regulate their proliferative potential. At each cell division the ends of linear chromosomes change and a cell becomes senescent when one or more of its telomeres ...
Abramowitz +26 more
core +1 more source