Results 31 to 40 of about 7,903,122 (310)

Can eukaryotic cells monitor the presence of unreplicated DNA?

open access: yesCell Division, 2007
Completion of DNA replication before mitosis is essential for genome stability and cell viability. Cellular controls called checkpoints act as surveillance mechanisms capable of detecting errors and blocking cell cycle progression to allow time for those
Aragón Luis   +2 more
doaj   +1 more source

The role of CDK in the initiation step of DNA replication in eukaryotes

open access: yesCell Division, 2007
Cyclin-dependent kinases (CDKs) regulate the progression of the cell cycle in eukaryotes. One of the major roles of CDK is to promote chromosomal DNA replication.
Tak Yon-Soo   +2 more
doaj   +1 more source

Reconstruction of the kinetochore: a prelude to meiosis

open access: yesCell Division, 2007
In eukaryotic organisms, chromosomes are spatially organized within the nucleus. Such nuclear architecture provides a physical framework for the genetic activities of chromosomes, and changes its functional organization as the cell moves through the ...
Haraguchi Tokuko   +2 more
doaj   +1 more source

A model for cell division [PDF]

open access: yesJournal of Biomechanics, 1980
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/23412/1/0000360 ...
openaire   +3 more sources

Mutations in ANKLE2, a ZIKA Virus Target, Disrupt an Asymmetric Cell Division Pathway in Drosophila Neuroblasts to Cause Microcephaly [PDF]

open access: yes, 2019
The apical Par complex, which contains atypical protein kinase C (aPKC), Bazooka (Par-3), and Par-6, is required for establishing polarity during asymmetric division of neuroblasts in Drosophila, and its activity depends on L(2)gl.
Thomas, Ajay X.   +33 more
core   +2 more sources

How eggs arrest at metaphase II: MPF stabilisation plus APC/C inhibition equals Cytostatic Factor

open access: yesCell Division, 2007
Oocytes from higher chordates, including man and nearly all mammals, arrest at metaphase of the second meiotic division before fertilization. This arrest is due to an activity that has been termed 'Cytostatic Factor'.
Jones Keith T, Madgwick Suzanne
doaj   +1 more source

Modulation of Cell–Cell Interactions in Drosophila Oocyte Development

open access: yes, 2020
The Drosophila ovary offers a suitable model system to study the mechanisms that orchestrate diverse cellular processes. Oogenesis starts from asymmetric stem cell division, proper differentiation and the production of fully patterned oocytes equipped ...
Mayu Inaba, Matthew Antel
core   +1 more source

Merotelic attachments and non-homologous end joining are the basis of chromosomal instability

open access: yesCell Division, 2010
Although the large majority of solid tumors show a combination of mitotic spindle defects and chromosomal instability, little is known about the mechanisms that govern the initial steps in tumorigenesis.
van Wely Karel HM   +2 more
doaj   +1 more source

Cell Cycle Regulation by Heat Shock Transcription Factors

open access: yes, 2022
Cell division and cell cycle mechanism has been studied for 70 years. This research has revealed that the cell cycle is regulated by many factors, including cyclins and cyclin-dependent kinases (CDKs).
Naoki Hayashida   +2 more
core   +1 more source

p27kip1 at the crossroad between actin and microtubule dynamics

open access: yesCell Division, 2019
The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra   +5 more
doaj   +1 more source

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