Results 11 to 20 of about 7,903,122 (310)
The C. elegans embryo is a powerful model system for studying the mechanics of metazoan cell division. Its primary advantage is that the architecture of the syncytial gonad makes it possible to use RNAi to generate oocytes whose cytoplasm is reproducibly (typically >95%) depleted of targeted essential gene products via a process that does not depend ...
Karen, Oegema, Anthony A, Hyman
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Principles of dormancy evident in high-grade serous ovarian cancer
In cancer, dormancy refers to a clinical state in which microscopic residual disease becomes non-proliferative and is largely refractory to chemotherapy.
Trevor G. Shepherd, Frederick A. Dick
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In this review, we summarize the strategies of inducing division in synthetic cells by using physical, chemical, and biological stimuli, and highlight the future challenges to the construction of autonomous synthetic cell division.
Mu-Yueh Chang +3 more
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Cell Division: The Prehistorichore? [PDF]
The recent discovery of a novel kinetochore has important implications for our understanding of the evolution of chromosome segregation systems and also for the treatment of devastating parasitic diseases.
Cane, Stuart, Maresca, Thomas J.
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A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1 [PDF]
Epithelial cell divisions are coordinated with cell loss to preserve epithelial integrity. However, how epithelia adapt their rate of cell division to changes in cell number, for instance during homeostatic turnover or wounding, is not well understood ...
Gómez González, Manuel +28 more
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Cell division in Corynebacterineae [PDF]
Bacterial cells must coordinate a number of events during the cell cycle. Spatio-temporal regulation of bacterial cytokinesis is indispensable for the production of viable, genetically identical offspring. In many rod-shaped bacteria, precise midcell assembly of the division machinery relies on inhibitory systems such as Min and Noc.
Donovan, Catriona, Bramkamp, Marc
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Endothelial cell division in angiogenic sprouts of differing cellular architecture [PDF]
The vasculature of the zebrafish trunk is composed of tubes with different cellular architectures. Unicellular tubes form their lumen through membrane invagination and transcellular cell hollowing, whereas multicellular vessels become lumenized through a
Markus Affolter +17 more
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Genetic control of plant development by overriding a geometric division rule [PDF]
Formative cell divisions are critical for multicellular patterning. In the early plant embryo, such divisions follow from orienting the division plane.
Barbier de Reuille, Pierre +26 more
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Chromosome segregation impacts on cell growth and division site selection in Corynebacterium glutamicum. [PDF]
Spatial and temporal regulation of bacterial cell division is imperative for the production of viable offspring. In many rod-shaped bacteria, regulatory systems such as the Min system and nucleoid occlusion ensure the high fidelity of midcell divisome ...
Marc Bramkamp +11 more
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Restriction beyond the restriction point: mitogen requirement for G2 passage
Cell proliferation is dependent on mitogenic signalling. When absent, normal cells cannot pass the G1 restriction point, resulting in cell cycle arrest.
te Riele Hein, Foijer Floris
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