Results 1 to 10 of about 3,524,174 (306)

Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development

open access: yesEpigenetics & Chromatin, 2022
Testis development and sustained germ cell production in adults rely on the establishment and maintenance of spermatogonia stem cells and their proper differentiation into spermatocytes.
Rodrigo O. de Castro   +5 more
doaj   +1 more source

Cell Cycle Regulation [PDF]

open access: yesFly, 2007
Drosophila researchers met in sunny San Diego for the 49th annual meeting of The Genetics Society of America. It was cold outside and even colder inside. Like last year, ‘Mitosis, Meiosis and Cell Division’ was no longer a session. Instead, we searched out and covered talks and posters in ‘Cell Division and Growth Control’, ‘Gametogenesis ...
Kristin, Garcia   +2 more
openaire   +2 more sources

DNA damage triggers squamous metaplasia in human lung and mammary cells via mitotic checkpoints

open access: yesCell Death Discovery, 2023
Epithelial transdifferentiation is frequent in tissue hyperplasia and contributes to disease in various degrees. Squamous metaplasia (SQM) precedes epidermoid lung cancer, an aggressive and frequent malignancy, but it is rare in the epithelium of the ...
Lucía San Juan   +9 more
doaj   +1 more source

A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching

open access: yesiScience, 2022
Summary: The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator.
Rodrigo Fraile   +4 more
doaj   +1 more source

miR-17 ~ 92 suppresses proliferation and invasion of cervical cancer cells by inhibiting cell cycle regulator Cdt2

open access: yesDiscover Oncology, 2023
Cervical cancer (CC) is the 4th most leading cause of death among women worldwide, and if diagnosed in late stages the treatment options are almost negligible. 99% of CC is caused by high-risk human papilloma viruses (HR-HPV). Upon integration into human
Garima Singh   +3 more
doaj   +1 more source

Do Cells Cycle? [PDF]

open access: yesProceedings of the National Academy of Sciences, 1973
We propose that a cell's life is divided into two fundamentally different parts. Some time after mitosis all cells enter a state (A) in which their activity is not directed towards replication. A cell may remain in the A-state for any lenght of time, throughout which its probability of leaving A-state remains constant. On leaving A-state, cells enter B-
J A, Smith, L, Martin
openaire   +2 more sources

Cell cycle length, cell size, and proliferation rate in hydra stem cells [PDF]

open access: yes, 1990
We have analyzed the cell cycle parameters of interstitial cells in Hydra oligactis. Three subpopulations of cells with short, medium, and long cell cycles were identified. Short-cycle cells are stem cells; medium-cycle cells are precursors to nematocyte
Bode   +34 more
core   +1 more source

The cell cycle program of polypeptide labeling in Chlamydomonas reinhardtii [PDF]

open access: yes, 1977
The cell cycle program of polypeptide labeling in syndhronous cultures of wild-type Chlamydomonas reinhardtii was analyzed by pulse-labeling cells with 35SO4 = or [3H]arginine at different cell cycle stages.
Hill, Kim R.   +2 more
core   +5 more sources

Cortical Cyclin A controls spindle orientation during asymmetric cell divisions in Drosophila

open access: yesNature Communications, 2022
The Frizzled/Dishevelled planar cell polarity pathway is involved in mitotic spindle orientation, but how this is coordinated with the cell cycle is unclear.
Pénélope Darnat   +6 more
doaj   +1 more source

The cell cycle [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2011
‘Dividing cells pass through a regular sequence of cell growth and division, known as the cell cycle’, according to a college textbook of biology published in 1983 [[1][1]], 5 years before the underlying principles of control were first laid bare during 1988, the annus mirabilis of cell ...
Hunt, T, Nasmyth, K, Novák, B
openaire   +1 more source

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