Results 11 to 20 of about 8,789,133 (312)

Cell Cycle Commitment and the Origins of Cell Cycle Variability [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Exit of cells from quiescence following mitogenic stimulation is highly asynchronous, and there is a great deal of heterogeneity in the response. Even in a single, clonal population, some cells re-enter the cell cycle after a sub-optimal mitogenic signal while other, seemingly identical cells, do not, though they remain capable of responding to a ...
Robert F. Brooks, Robert F. Brooks
openaire   +6 more sources

The Cell Cycle [PDF]

open access: yesThe Oncologist, 2000
The Oncologist 2000;5:510-513 www.TheOncologist.com Correspondence: L.G. Israels, M.D., Manitoba Institute of Cell Biology, University of Manitoba, 100 Olivia Street, Winnipeg, Manitoba, Canada, R3E 0V9. Telephone: 204-787-2246; Fax: 204-787-1345; e-mail: lisraels@cc.umanitoba.ca Received August 22, 2000; accepted for publication August 22, 2000 ...
E D, Israels, L G, Israels
openaire   +3 more sources

The cell cycle [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2011
‘Dividing cells pass through a regular sequence of cell growth and division, known as the cell cycle’, according to a college textbook of biology published in 1983 [[1][1]], 5 years before the underlying principles of control were first laid bare during 1988, the annus mirabilis of cell ...
Hunt, T, Nasmyth, K, Novák, B
openaire   +1 more source

The Cell Cycle is a Limit Cycle [PDF]

open access: yesMathematical Modelling of Natural Phenomena, 2012
Progression along the successive phases of the mammalian cell cycle is driven by a network of cyclin-dependent kinases (Cdks). This network is regulated by a variety of negative and positive feedback loops. We previously proposed a detailed, 39-variable model for the Cdk network and showed that it is capable of temporal self-organization in the form of
Gérard, Claude, Goldbeter, Albert
openaire   +2 more sources

MAST4 controls cell cycle in spermatogonial stem cells [PDF]

open access: yes, 2023
Spermatogonial stem cell (SSC) self-renewal is regulated by reciprocal interactions between Sertoli cells and SSCs in the testis. In a previous study, microtubule-associated serine/threonine kinase 4 (MAST4) has been studied in Sertoli cells as a ...
정한성, 이동준
core   +2 more sources

Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase [PDF]

open access: yes, 2014
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic ...
Jaiswal, H.   +9 more
core   +1 more source

Nek family of kinases in cell cycle, checkpoint control and cancer [PDF]

open access: yes, 2011
Early studies in lower Eukaryotes have defined a role for the members of the NimA related kinase (Nek) family of protein kinases in cell cycle control. Expansion of the Nek family throughout evolution has been accompanied by their broader involvement in ...
Haider Nasir   +15 more
core   +1 more source

Cell cycle length, cell size, and proliferation rate in hydra stem cells [PDF]

open access: yes, 1990
We have analyzed the cell cycle parameters of interstitial cells in Hydra oligactis. Three subpopulations of cells with short, medium, and long cell cycles were identified. Short-cycle cells are stem cells; medium-cycle cells are precursors to nematocyte
Charles   +4 more
core   +1 more source

Acanthamoeba induces cell-cycle arrest in host cells [PDF]

open access: yes, 2004
Acanthamoeba can cause fatal granulomatous amoebic encephalitis (GAE) and eye keratitis. However, the pathogenesis and pathophysiology of these emerging diseases remain unclear.
Alsam, S.   +5 more
core   +1 more source

Fate specification and tissue-specific cell cycle control of the Caenorhabditis elegans intestine [PDF]

open access: yes, 2010
Coordination between cell fate specification and cell cycle control in multicellular organisms is essential to regulate cell numbers in tissues and organs during development, and its failure may lead to oncogenesis.
Segref, Alexandra   +9 more
core   +1 more source

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