Results 31 to 40 of about 8,365,967 (315)

Keap1 modulates the redox cycle and hepatocyte cell cycle in regenerating liver [PDF]

open access: yes, 2014
Keap1 negatively controls the activity of transcription factor Nrf2. This Keap1/Nrf2 pathway plays a critical role in combating oxidative stress. We aimed at determining whether and how Keap1 modulates the cell cycle of replicating hepatocytes during ...
Zou, Yuhong   +5 more
core   +1 more source

Cell cycle analysis of primary sponge cell cultures [PDF]

open access: yes, 2011
Proliferation of sponge cells is generally measured via cell counts or viability assays. However, more insight into the proliferative state of a sponge cell population can be obtained from the distribution of the cells over the different phases of the ...
Pomponi, S.A.   +7 more
core   +1 more source

MAST4 controls cell cycle in spermatogonial stem cells [PDF]

open access: yes, 2023
Spermatogonial stem cell (SSC) self-renewal is regulated by reciprocal interactions between Sertoli cells and SSCs in the testis. In a previous study, microtubule-associated serine/threonine kinase 4 (MAST4) has been studied in Sertoli cells as a ...
정한성, 이동준
core   +2 more sources

Conditional control of fluorescent protein degradation by an auxin-dependent nanobody

open access: yesNature Communications, 2018
Current approaches to conditionally deplete target proteins require site-specific genetic engineering or have poor temporal control. Here the authors overcome these limitations by combining the AID system with nanobodies to reversibly degrade GFP-tagged ...
Katrin Daniel   +5 more
doaj   +1 more source

IRBIT Directs Differentiation of Intestinal Stem Cell Progeny to Maintain Tissue Homeostasis

open access: yesiScience, 2020
Summary: The maintenance of the intestinal epithelium is ensured by the controlled proliferation of intestinal stem cells (ISCs) and differentiation of their progeny into various cell types, including enterocytes (ECs) that both mediate nutrient ...
Alexei Arnaoutov   +7 more
doaj   +1 more source

Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus

open access: yesNature Communications, 2016
The small molecule (p)ppGpp is commonly produced by bacteria as a signal of nutrient starvation. Here, Ronneau et al. show that (p)ppGpp accumulation in the model bacterium Caulobacter crescentusis modulated by a nitrogen-related phosphotransferase ...
Séverin Ronneau   +3 more
doaj   +1 more source

Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging

open access: yesBMC Biology, 2022
Background In many organisms, aging is characterized by a loss of mitochondrial homeostasis. Multiple factors such as respiratory metabolism, mitochondrial fusion/fission, or mitophagy have been linked to cell longevity, but the exact impact of each one ...
Montserrat Vega   +6 more
doaj   +1 more source

Metabolic control of cell division in α-proteobacteria by a NAD-dependent glutamate dehydrogenase

open access: yesCommunicative & Integrative Biology, 2016
Prior to initiate energy-consuming processes, such as DNA replication or cell division, cells need to evaluate their metabolic status. We have recently identified and characterized a new connection between metabolism and cell division in the α ...
François Beaufay   +2 more
doaj   +1 more source

Comparing Mitochondrial Activity, Oxidative Stress Tolerance, and Longevity of Thirteen Ascomycota Yeast Species

open access: yesAntioxidants, 2023
Aging is characterized by a number of hallmarks including loss of mitochondrial homeostasis and decay in stress tolerance, among others. Unicellular eukaryotes have been widely used to study chronological aging.
Anna Gröger   +5 more
doaj   +1 more source

Cell Cycle Regulation [PDF]

open access: yesFly, 2008
Drosophila researchers met in sunny San Diego for the 49(th) Annual Meeting of The Genetics Society of America. It was cold outside and even colder inside. Like last year, 'Mitosis, Meiosis and Cell Division' was no longer a session. Instead, we searched out and covered talks and posters in 'Cell Division and Growth Control', 'Gametogenesis ...
Kristin, Garcia, Tin Tin, Su
openaire   +2 more sources

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