Results 31 to 40 of about 3,524,174 (306)
Consequences of simulated microgravity in neural stem cells: biological effects and metabolic response. [PDF]
, 2015 Objective: Microgravity was often shown to cause cell damage and impair cell cycle in a variety of biological systems. Since the effects on the neural system were poorly investigated, we aimed to gain insight into how biological processes such as cell ...
ABBALLE, LUANA +15 more
core +1 more source
Biology Open, 2015 The deregulation of cell polarity or cytoskeletal regulators is a common occurrence in human epithelial cancers. Moreover, there is accumulating evidence in human epithelial cancer that BTB-ZF genes, such as Bcl6 and ZBTB7A, are oncogenic.
Nezaket Turkel +5 more
doaj +1 more source
WormBook, 2005 Cell-division control affects many aspects of development. Caenorhabditis elegans cell-cycle genes have been identified over the past decade, including at least two distinct Cyclin-Dependent Kinases (CDKs), their cyclin partners, positive and negative regulators, and downstream targets.
openaire +3 more sources
Hidden origami in Trypanosoma cruzi nuclei highlights its non-random 3D genomic organization
mBioThe protozoan Trypanosoma cruzi is the causative agent of Chagas disease and is known for its polycistronic transcription, with about 50% of its genome consisting of repetitive sequences, including coding (primarily multigenic families) and non-coding ...
Natália Karla Bellini +3 more
doaj +1 more source
Nature Communications, 2019 Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in response to
Mercè Carmona +8 more
doaj +1 more source
Physiological and transcriptomic evidence for a close coupling between chloroplast ontogeny and cell cycle progression in the pennate diatom Seminavis robusta [PDF]
, 2008 Despite the growing interest in diatom genomics, detailed time series of gene expression in relation to key cellular processes are still lacking. Here, we investigated the relationships between the cell cycle and chloroplast development in the pennate ...
Chepurnov, Victor A +12 more
core +3 more sources
Orphanet Journal of Rare Diseases, 2022 Background Novel developmental mutations associated with disease are a continuous challenge in medicine. Clinical consequences caused by these mutations include neuron and cognitive alterations that can lead to epilepsy or autism spectrum disorders ...
Jesús Galán-Vidal +8 more
doaj +1 more source
Epidermal growth factor-mediated T-cell factor/lymphoid enhancer factor transcriptional activity is essential but not sufficient for cell cycle progression in nontransformed mammary epithelial cells [PDF]
, 2004 Because beta-catenin target genes such as cyclin D1 are involved in cell cycle progression, we examined whether beta-catenin has a more pervasive role in normal cell proliferation, even upon stimulation by non-Wnt ligands.
Asthagiri, Anand R., Graham, Nicholas A.
core +1 more source
Cell Reports, 2020 Summary: Cells have developed protein quality-control strategies to manage the accumulation of misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission yeast, Rho1.C17R-GFP, we demonstrate that upon mild heat shock, the ...
Margarita Cabrera +6 more
doaj +1 more source
FEBS Open Bio, 2022 Over the past few decades, dozens of in vitro methods have been developed to map, investigate and validate protein–protein interactions. However, most of these approaches are time‐consuming and labour‐intensive or require specialised equipment or ...
Zsuzsánna Réthi‐Nagy +2 more
doaj +1 more source