peggyscshu/Mitosis-phase-analysis:
, 2021 A cell cycle occurs as a cell divides. The somatic cell leaves interphase, undergoes mitosis and eventually gives out two daughter cells. Mitosis is composed by a series of events including prophase, metaphase, anaphase and telophase.
Shao-Chun, Peggy, Hsu
core +1 more source
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis [PDF]
, 2005 Several kinases phosphorylate vimentin, the most common intermediate filament protein, in mitosis. Aurora-B and Rho-kinase regulate vimentin filament separation through the cleavage furrow-specific vimentin phosphorylation.
Erich A. Nigg +19 more
core +1 more source
Chromosome condensation in mitosis and meiosis of rye (Secale cereale L.) [PDF]
, 2004 Structural investigation and morphometry of meiotic chromosomes by scanning electron microscopy (in comparison to light microscopy) of all stages of condensation of meiosis I + II show remarkable differences during chromosome condensation in mitosis and ...
Herrmann, Reinhold G. +2 more
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Astrin is required for the maintenance of sister chromatid cohesion and centrosome integrity [PDF]
, 2007 Faithful chromosome segregation in mitosis requires the formation of a bipolar mitotic spindle with stably attached chromosomes. Once all of the chromosomes are aligned, the connection between the sister chromatids is severed by the cysteine protease ...
Erich A. Nigg +14 more
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Dual pathway spindle assembly increases both the speed and the fidelity of mitosis [PDF]
, 2011 Roughly half of all animal somatic cell spindles assemble by the classical prophase pathway, in which the centrosomes separate ahead of nuclear envelope breakdown (NEBD).
Robert A. Cross +5 more
core +1 more source
Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis [PDF]
, 1998 The spindle checkpoint ensures proper chromosome segregation by delaying anaphase until all chromosomes are correctly attached to the mitotic spindle.
Javerzat, Jean-Paul +8 more
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Exotic mitotic mechanisms [PDF]
, 2012 The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
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Functional characterization of PICH, a DNA-dependent ATPase required for faithful chromosome segregation during mitosis [PDF]
, 2010 PICH (Plk1-interacting checkpoint helicase), a DNA-dependent ATPase, was identified as a binding partner and substrate of Plk1. During mitosis, PICH localizes to the centromere/KTs of condensed mitotic chromosomes and to ultra-fine DNA bridges (UFBs ...
Kaulich, Manuel
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Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation [PDF]
, 2015 During mitosis, Bub1 kinase phosphorylates histone H2A-T120 to promote centromere sister chromatid cohesion through recruitment of shugoshin (Sgo) proteins. The regulation and dynamics of H2A-T120 phosphorylation are poorly understood. Using quantitative
Lajeunesse, Audrey +6 more
core +1 more source
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis [PDF]
, 2010 We have studied Sds22, a conserved regulator of protein phosphatase 1 (PP1) activity, and determined its role in modulating the activity of aurora B kinase and kinetochore-microtubule inter-actions.
DeLuca, Jennifer G. +11 more
core +1 more source