Results 31 to 40 of about 46,698 (168)

Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation

open access: yesOpen Biology, 2022
Lamin A phosphorylation/de-phosphorylation is an important process during cells division as it allows for nuclear envelope (NE) disassembly at mitotic entry and its re-assembly during mitotic exit.
Florentin Huguet   +4 more
doaj   +1 more source

Automated mitosis detection in histopathology using morphological and multi-channel statistics features

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations.
Humayun Irshad
doaj   +1 more source

Investigation of FEAR and MEN pathway homologs in multinucleate cells [PDF]

open access: yes, 2011
The cell cycle is a sequence of events enabling a cell to replicate and proliferate. Common landmark events in most eukaryotic cell cycles are duplication of the DNA, mitosis, and cell separation.
Finlayson, Mark
core   +1 more source

53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis

open access: yeseLife, 2016
Mitosis occurs efficiently, but when it is disturbed or delayed, p53-dependent cell death or senescence is often triggered after mitotic exit. To characterize this process, we conducted CRISPR-mediated loss-of-function screens using a cell-based assay in
Chii Shyang Fong   +7 more
doaj   +1 more source

PartMitosis: A Partially Supervised Deep Learning Framework for Mitosis Detection in Breast Cancer Histopathology Images

open access: yesIEEE Access, 2020
Detection of mitotic tumor cells per tissue area is one of the critical markers of breast cancer prognosis. The aim of this paper is to develop a method for the automatic detection of mitotic figures from breast cancer histological slides using a ...
Meriem Sebai   +2 more
doaj   +1 more source

PREEParing for Mitosis [PDF]

open access: yesDevelopmental Cell, 2013
Reporting in Developmental Cell, Schlaitz et al. (2013) show that endoplasmic reticulum (ER) membrane exclusion from the mitotic spindle is an active process requiring REEP membrane proteins. REEP protein depletion results in ER membrane retention on the spindle and chromosomes, leading to defects in chromosome segregation and nuclear envelope assembly.
openaire   +2 more sources

The Biochemistry of Mitosis [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2015
In this article, we will discuss the biochemistry of mitosis in eukaryotic cells. We will focus on conserved principles that, importantly, are adapted to the biology of the organism. It is vital to bear in mind that the structural requirements for division in a rapidly dividing syncytial Drosophila embryo, for example, are markedly different from those
Samuel, Wieser, Jonathon, Pines
openaire   +2 more sources

Mitosis Detection in Breast Histopathology Images Using a Self-Attention-Enhanced Faster R-CNN Framework

open access: yesIEEE Access
At present, mitosis detection in breast histopathology images is a critical issue for breast cancer grading. Due to the breast tissue having a complex structure, and mitosis and non-mitosis cells being similar to each other, traditional methods for ...
Sarah Ayashm   +3 more
doaj   +1 more source

Mitosis sans Mitosis: The Mitotic Oscillator in Differentiation [PDF]

open access: yesDevelopmental Cell, 2017
Differentiation and proliferation are usually considered to be antagonistic partners in development. However, in a recent issue of Science, Al Jord et al. (2017) show that key regulators of the mitotic cycle are redeployed in differentiating multiciliated cells to promote ciliogenesis without mitotic progression.
Miranda, Stratton, Tim, Stearns
openaire   +2 more sources

Examples of Mitosis and Not mitosis images.

open access: yes, 2016
(a) The cropped image for “Mitosis” scanned by Aperio. (b) The cropped image for “Not mitosis” scanned by Aperio. (c) The cropped image for “Mitosis” scanned by Hamamatsu. (d) The cropped image for “Not mitosis” scanned by Hamamatsu.
Kenji Watanabe (75040)   +2 more
core   +1 more source

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