Results 31 to 40 of about 44,803 (256)

Functional characterization of PICH, a DNA-dependent ATPase required for faithful chromosome segregation during mitosis [PDF]

open access: yes, 2010
PICH (Plk1-interacting checkpoint helicase), a DNA-dependent ATPase, was identified as a binding partner and substrate of Plk1. During mitosis, PICH localizes to the centromere/KTs of condensed mitotic chromosomes and to ultra-fine DNA bridges (UFBs ...
Kaulich, Manuel
core   +1 more source

Polo-like kinase 1 (PLK1) and protein phosphatase 6 (PP6) regulate DNA-dependent protein kinase catalytic subunit (DNA-PKcs) phosphorylation in mitosis

open access: yesBioscience Reports, 2014
The protein kinase activity of the DNA-PKcs (DNA-dependent protein kinase catalytic subunit) and its autophosphorylation are critical for DBS (DNA double-strand break) repair via NHEJ (non-homologous end-joining). Recent studies have shown that depletion
Pauline Douglas   +7 more
doaj   +1 more source

Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis [PDF]

open access: yes, 2010
We have studied Sds22, a conserved regulator of protein phosphatase 1 (PP1) activity, and determined its role in modulating the activity of aurora B kinase and kinetochore-microtubule inter-actions.
DeLuca, Jennifer G.   +11 more
core   +1 more source

Radiation and electron microscope studies on Euglenphyceae [PDF]

open access: yes, 1977
PhDTwo species of Euglena, Euglena gracilis and Eug1ena mutabilis, were cultured with the object of finding the conditions which would give the highest mitotic index at a predictable time.
Shahanara, Sufia
core   +4 more sources

Biophysics of mitosis [PDF]

open access: yesQuarterly Reviews of Biophysics, 2012
AbstractMitosis is the process by which eukaryotic cells organize and segregate their chromosomes in preparation for cell division. It is accomplished by a cellular machine composed largely of microtubules (MTs) and their associated proteins. This article reviews literature on mitosis from a biophysical point of view, drawing attention to the assembly ...
J Richard, McIntosh   +2 more
openaire   +2 more sources

Automated mitosis detection using texture, SIFT features and HMAX biologically inspired approach

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count in breast cancer histopathology is one of three components required for cancer grading and prognosis. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader
Humayun Irshad   +6 more
doaj   +1 more source

Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation [PDF]

open access: yes, 2015
During mitosis, Bub1 kinase phosphorylates histone H2A-T120 to promote centromere sister chromatid cohesion through recruitment of shugoshin (Sgo) proteins. The regulation and dynamics of H2A-T120 phosphorylation are poorly understood. Using quantitative
Lajeunesse, Audrey   +6 more
core   +1 more source

Mitosis Methods & Protocols

open access: yesEuropean Journal of Histochemistry, 2010
Mitosis Methods & Protocols Andrew D. McAinsh (Edt) Humana press, Totowa, New Jersey (USA) Series: Springer Protocols Methods in Molecular Biology, Volume 545, 2009 ISBN: 978-1-60327-992-5   It is quite clear from the contents of this book that
CarloAlberto Redi
doaj   +1 more source

Automated mitosis detection in histopathology using morphological and multi-channel statistics features

open access: yesJournal of Pathology Informatics, 2013
Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations.
Humayun Irshad
doaj   +1 more source

Repo-Man/protein phosphatase 1 SUMOylation mediates binding to lamin A and serine 22 dephosphorylation

open access: yesOpen Biology, 2022
Lamin A phosphorylation/de-phosphorylation is an important process during cells division as it allows for nuclear envelope (NE) disassembly at mitotic entry and its re-assembly during mitotic exit.
Florentin Huguet   +4 more
doaj   +1 more source

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