Results 51 to 60 of about 195,442 (311)

Recent Research Advances in Mitosis during Mammalian Gametogenesis

Cells, 2019
Mitosis is a highly sophisticated and well-regulated process during the development and differentiation of mammalian gametogenesis. The regulation of mitosis plays an essential role in keeping the formulation in oogenesis and gametogenesis.
Jia-Hao Wang, Yan Li, Shou-Long Deng, Yi-Xun Liu, Zheng-Xing Lian, Kun Yu   +5 more
doaj   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Mitosis detection in histopathological images using customized deep learning and hybrid optimization algorithms.

PLoS ONE
Identifying mitosis is crucial for cancer diagnosis, but accurate detection remains difficult because of class imbalance and complex morphological variations in histopathological images.
Afnan M Alhassan, Nouf I Altmami
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Ki-67 is a PP1-interacting protein that organises the mitotic chromosome periphery [PDF]

, 2014
Copyright @ 2014 Booth et al. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.When the nucleolus ...
Elizabeth Petfalski, Vagnarelli, Paola, Ponting, Christopher, David Tollervey, Earnshaw, William C, Imamoto, N, Petfalski, Elizabeth, Sanchez-Pulido, Luis, Giulia Vargiu, Takagi, M, Booth, DG, Luis Sanchez-Pulido, Tollervey, David, Ponting, Chris P, Petfalski, E, Ponting, CP, Vargiu, Giulia, Tollervey, D, Naoko Imamoto, Ponting, Chris P.; id_orcid, Earnshaw, William C., Daniel G Booth, Vagnarelli, P, Kumiko Samejima, Imamoto, Naoko, Booth, Daniel G, William C Earnshaw, Masatoshi Takagi, Samejima, Kumiko, Sanchez-Pulido, L, Vargiu, G, Booth, Daniel G., Chris P Ponting, Paola Vagnarelli, Takagi, Masatoshi, Samejima, K, Earnshaw, WC   +36 more
core   +1 more source

Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest

Cell Reports, 2014
Mitosis is a moment of exquisite vulnerability for a metazoan cell. Failure to complete mitosis accurately can lead to aneuploidy and cancer initiation.
Pengbo Wang, Jennefer Lindsay, Thomas W. Owens, Ewa J. Mularczyk, Stacey Warwood, Fiona Foster, Charles H. Streuli, Keith Brennan, Andrew P. Gilmore   +8 more
doaj   +1 more source

Long-Term Wi-Fi Exposure From Pre-Pubertal to Adult Age on the Spermatogonia Proliferation and Protective Effects of Edible Bird’s Nest Supplementation

Frontiers in Physiology, 2022
Children are vulnerable to the radiofrequency radiation (RFR) emitted by Wi-Fi devices. Nevertheless, the severity of the Wi-Fi effect on their reproductive development has been sparsely available.
Farah Hanan Fathihah Jaffar, Khairul Osman, Chua Kien Hui, Aini Farzana Zulkefli, Siti Fatimah Ibrahim   +4 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Examples of Mitosis and Not mitosis images.

, 2016
(a) The cropped image for “Mitosis” scanned by Aperio. (b) The cropped image for “Not mitosis” scanned by Aperio. (c) The cropped image for “Mitosis” scanned by Hamamatsu. (d) The cropped image for “Not mitosis” scanned by Hamamatsu.
Kenji Watanabe (75040), Takumi Kobayashi (733305), Toshikazu Wada (3375416)   +2 more
core   +1 more source

Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1

eLife, 2020
The inner nuclear membrane is functionalized by diverse transmembrane proteins that associate with nuclear lamins and/or chromatin. When cells enter mitosis, membrane-chromatin contacts must be broken to allow for proper chromosome segregation; yet how ...
Naemi Luithle, Jelmi uit de Bos, Ruud Hovius, Daria Maslennikova, Renard TM Lewis, Rosemarie Ungricht, Beat Fierz, Ulrike Kutay   +7 more
doaj   +1 more source