Results 61 to 70 of about 312,064 (187)
Addressing a weakness of anticancer therapy with mitosis inhibitors: Mitotic slippage
Molecular & Cellular Oncology, 2017 Mitosis inhibitors, which include antimicrotubule drugs, are chemotherapy agents that induce the arrest and apoptosis of mitotic cells. Mitotic slippage, in which mitotically arrested cells exit mitosis, limits the effectiveness of mitosis inhibitors. We
Riju S. Balachandran, Edward T. Kipreos
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Role of Intermediate Filaments in Vesicular Traffic
Cells, 2016 Intermediate filaments are an important component of the cellular cytoskeleton. The first established role attributed to intermediate filaments was the mechanical support to cells.
Azzurra Margiotta, Cecilia Bucci
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E3 Ubiquitin Ligase TRIM Proteins, Cell Cycle and Mitosis
Cells, 2019 The cell cycle is a series of events by which cellular components are accurately segregated into daughter cells, principally controlled by the oscillating activities of cyclin-dependent kinases (CDKs) and their co-activators.
Santina Venuto, Giuseppe Merla
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Indeks Mitosis Venereal Sarcoma pada Anjing Lokal di Denpasar
Indonesia Medicus Veterinus, 2014 Penelitian ini bertujuan untuk mengetahui rataan indeks mitosis serta perbedaan rataan indeks mitosis kasus venereal sarcoma pada anjing lokal jantan dan betina di Denpasar.
Fathurohman Nasrudin +2 more
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A simple biophysical model emulates budding yeast chromosome condensation
eLife, 2015 Mitotic chromosomes were one of the first cell biological structures to be described, yet their molecular architecture remains poorly understood. We have devised a simple biophysical model of a 300 kb-long nucleosome chain, the size of a budding yeast ...
Tammy MK Cheng +8 more
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PLoS GeneticsStem and progenitor cell mitosis is essential for tissue development and homeostasis. How these cells ensure proper chromosome segregation, and thereby maintain mitotic fidelity, in the complex physiological environment of a living animal is poorly ...
Eric Cheng, Ran Lu, Abigail R Gerhold
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eLife, 2013 Experiments in Xenopus embryo extracts reveal that changes in cellular biochemistry cause mitotic spindles to decrease in size over the course of early development.
Daniel Needleman
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The coordination of nuclear envelope assembly and chromosome segregation in metazoans
Nucleus, 2020 The nuclear envelope (NE) is composed of two lipid bilayer membranes that enclose the eukaryotic genome. In interphase, the NE is perforated by thousands of nuclear pore complexes (NPCs), which allow transport in and out of the nucleus. During mitosis in
Shiwei Liu, David Pellman
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Splicing factors Sf3A2 and Prp31 have direct roles in mitotic chromosome segregation
eLife, 2018 Several studies have shown that RNAi-mediated depletion of splicing factors (SFs) results in mitotic abnormalities. However, it is currently unclear whether these abnormalities reflect defective splicing of specific pre-mRNAs or a direct role of the SFs ...
Claudia Pellacani +9 more
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Ki-67 and CDK1 control the dynamic association of nuclear lipids with mitotic chromosomes
Journal of Lipid ResearchNuclear lipids play roles in regulatory processes, such as signaling, transcriptional regulation, and DNA repair. In this report, we demonstrate that nuclear lipids may contribute to Ki-67-regulated chromosome integrity during mitosis.
Hsiao-Tang Hu +4 more
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