Results 71 to 80 of about 312,064 (187)

Mitotic progression, arrest, exit or death relies on centromere structural integrity, rather than de novo transcription

eLife, 2018
Recent studies have challenged the prevailing dogma that transcription is repressed during mitosis. Transcription was also proposed to sustain a robust spindle assembly checkpoint (SAC) response.
Marco Novais-Cruz, Maria Alba Abad, Wilfred FJ van IJcken, Niels Galjart, A Arockia Jeyaprakash, Helder Maiato, Cristina Ferrás   +6 more
doaj   +1 more source

Mitotic antipairing of homologous and sex chromosomes via spatial restriction of two haploid sets. [PDF]

, 2018
Pairing homologous chromosomes is required for recombination. However, in nonmeiotic stages it can lead to detrimental consequences, such as allelic misregulation and genome instability, and is rare in human somatic cells.
Hua, Lisa L, Mikawa, Takashi
core   +1 more source

Unveiling an Arpp-19 phosphorylation switch that grants chromosome stability

Communications Biology
During cell division, the onset of mitosis is granted by activation of cyclin B-dependent kinase 1 (Cdk1), master mitotic kinase, coordinated with inactivation of Cdk1-counteracting phosphatases.
Angela Flavia Serpico, Caterina Pisauro, Asia Trano, Domenico Grieco   +3 more
doaj   +1 more source

Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos

Frontiers in Cell and Developmental Biology
To form tissues with unique functions and structures, it is important that the cells that comprise them maintain physical contact. On the other hand, with each mitosis, drastic changes in cell shapes, cell adhesion, and cytoskeletal architecture may ...
Hideko Utsumi, Hideko Utsumi, Taijiro Yabe, Taijiro Yabe, Taijiro Yabe, Sumito Koshida, Sumito Koshida, Sumito Koshida, Akira Yamashita, Akira Yamashita, Akira Yamashita, Shinji Takada, Shinji Takada, Shinji Takada   +13 more
doaj   +1 more source

Phosphorylated ERK5/BMK1 transiently accumulates within division spindles in mouse oocytes and preimplantation embryos

Folia Histochemica et Cytobiologica, 2011
MAP kinases of the ERK family play important roles in oocyte maturation, fertilization, and early embryo development. The role of the signaling pathway involving ERK5 MAP kinase during meiotic and mitotic M-phase of the cell cycle is not well known. Here,
Maria A. Ciemerych, Jacek Z. Kubiak, Aude Pascal, Zuzanna Maciejewska   +3 more
doaj   +1 more source

The mechanism regulating the dissociation of the centrosomal protein C-Nap1 from mitotic spindle poles [PDF]

, 2002
The centrosomal protein C-Nap1 is thought to play an important role in centrosome cohesion during interphase of the cell cycle. At the onset of mitosis, when centrosomes separate for bipolar spindle formation, C-Nap1 dissociates from centrosomes. Here we
Hacker, Ulrike, Mayor, Thibault, Nigg, Erich A., Stierhof, York-Dieter   +3 more
core  

Kinesins regulate the heterogeneity in centrosome clustering after whole-genome duplication

Life Science Alliance
Kinesin levels determine mitotic spindle polarity after whole-genome duplication. After whole-genome duplication (WGD), tetraploid cells can undergo multipolar mitosis or pseudo-bipolar mitosis with clustered centrosomes.
Thomas TY Lau, Hoi Tang Ma, Randy YC Poon   +2 more
doaj   +1 more source

Augmented Mitotic Cell Count using Field Of Interest Proposal

, 2018
Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count (MC), i.e ...
Aubreville, Marc, Bertram, Christof A., Klopfleisch, Robert, Maier, Andreas   +3 more
core   +1 more source

Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]

, 1994
The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Bridger, JM, Cox, LS, Hutchison, CJ, Kill, IR   +3 more
core  

Mitosis

, 2014
Citation: 'mitosis' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03938 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage
openaire   +2 more sources