Results 21 to 30 of about 7,478,668 (259)

Cell Division Compromises Epithelial Cell Polarity and Drives Tumor Progression

open access: yes, 2021
Epithelia are the predominant tissue type of the animal body and form major components of most organs. As with all tissues, the formation of epithelia during development and their stem cell-based renewal requires cell division. This presents a problem as
Jeyanathan, Gayaanan
core   +1 more source

Cell division orientation in animals [PDF]

open access: yes, 2011
Cell division orientation during animal development can serve to correctly organize and shape tissues, create cellular diversity or both. The underlying cellular mechanism is regulated spindle orientation.
Gillies, Taryn E.   +3 more
core   +1 more source

A mechanical G2 checkpoint controls epithelial cell division through E-cadherin-mediated regulation of Wee1-Cdk1 [PDF]

open access: yes, 2022
Epithelial cell divisions are coordinated with cell loss to preserve epithelial integrity. However, how epithelia adapt their rate of cell division to changes in cell number, for instance during homeostatic turnover or wounding, is not well understood ...
Gómez González, Manuel   +25 more
core   +1 more source

p27kip1 at the crossroad between actin and microtubule dynamics

open access: yesCell Division, 2019
The p27kip1 protein, mainly known as a negative regulator of cell proliferation, has also been involved in the control of other cellular processes, including the regulation of cytoskeleton dynamics.
Gian Luca Rampioni Vinciguerra   +5 more
doaj   +1 more source

Modulation of Cell–Cell Interactions in Drosophila Oocyte Development

open access: yes, 2020
The Drosophila ovary offers a suitable model system to study the mechanisms that orchestrate diverse cellular processes. Oogenesis starts from asymmetric stem cell division, proper differentiation and the production of fully patterned oocytes equipped ...
Mayu Inaba, Matthew Antel
core   +1 more source

Mechanisms for the temporal regulation of substrate ubiquitination by the anaphase-promoting complex/cyclosome

open access: yesCell Division, 2019
The anaphase-promoting complex/cyclosome (APC/C) is a multi-subunit, multifunctional ubiquitin ligase that controls the temporal degradation of numerous cell cycle regulatory proteins to direct the unidirectional cell cycle phases.
Shivangee Bansal, Swati Tiwari
doaj   +1 more source

JAB1/CSN5: a new player in cell cycle control and cancer

open access: yesCell Division, 2010
c-Jun activation domain-binding protein-1 (Jab1) acts as a modulator of intracellular signaling and affects cellular proliferation and apoptosis, through its existence as a monomer or as the fifth component of the constitutive photomorphogenic-9 ...
Claret Francois X, Shackleford Terry J
doaj   +1 more source

Expression of genes regulating cell division in porcine follicular granulosa cells

open access: yesCell Division, 2023
Background Cell cycle regulation influences the proliferation of granulosa cells and affects many processes related to ovarian folliclular growth and ovulation. Abnormal regulation of the cell cycle can lead to many diseases within the ovary.
Jakub Kulus   +7 more
doaj   +1 more source

Resolving RAD51C function in late stages of homologous recombination

open access: yesCell Division, 2007
DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
doaj   +1 more source

Rapid and accurate genotyping of human SNP rs671 in aldehyde dehydrogenase 2 gene using one-step CRISPR/Cas12b assay without DNA amplification

open access: yesCell Division, 2023
Background The SNP rs671 of Human aldehyde dehydrogenase (ALDH) is G-A transition at 1510th nucleotides, which is an important clinical indicator of alcoholic liver disease, digestive tract cancer and some drug efficiency.
Fang Wu   +6 more
doaj   +1 more source

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