Results 41 to 50 of about 15,182,492 (337)
Resolving RAD51C function in late stages of homologous recombination
Cell Division, 2007 DNA double strand breaks are efficiently repaired by homologous recombination. One of the last steps of this process is resolution of Holliday junctions that are formed at the sites of genetic exchange between homologous DNA.
Kuznetsov Sergey G, Sharan Shyam K
doaj +1 more source
Cell Division, 2023 Background The SNP rs671 of Human aldehyde dehydrogenase (ALDH) is G-A transition at 1510th nucleotides, which is an important clinical indicator of alcoholic liver disease, digestive tract cancer and some drug efficiency.
Fang Wu +6 more
doaj +1 more source
Polarized Cell Division of Chlamydia trachomatis
PLoS Pathogens, 2016 Bacterial cell division predominantly occurs by a highly conserved process, termed binary fission, that requires the bacterial homologue of tubulin, FtsZ. Other mechanisms of bacterial cell division that are independent of FtsZ are rare.
Yasser M. Abdelrahman +3 more
semanticscholar +1 more source
Deficiency of RgpG causes major defects in cell division and biofilm formation, and deficiency of LytR-CpsAPsr family proteins leads to accumulation of cell wall antigens in culture medium by Streptococcus mutans [PDF]
, 2017 Streptococcus mutans is known to possess rhamnose-glucose polysaccharide (RGP), a major cell wall antigen. S. mutans strains deficient in rgpG , encoding the first enzyme of the RGP biosynthesis
Beatty, Wandy L +6 more
core +2 more sources
CLK3 promotes tumor proliferation by activating MYC signaling
Cell DivisionColorectal cancer (CRC) ranks among the leading causes of cancer-related mortality worldwide, posing a significant public health challenge. Despite advancements in treatment strategies, prognosis for advanced CRC remains poor.
Jing Shen, Yu Zhao, Yang Man, Xuling Sun
doaj +1 more source
Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis
Cell Division, 2007 Haematopoietic cell number is maintained by a delicate balance between cell proliferation, differentiation and death. Gene knockout studies in mice have revealed the complex roles of cyclins, CDKs, and CDK inhibitors in regulating cell proliferation and ...
Lam Eric, Myatt Stephen S
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MPS1 is involved in the HPV16-E7-mediated centrosomes amplification
Cell Division, 2021 Background It has been reported that the oncoprotein E7 from human papillomavirus type 16 (HPV16-E7) can induce the excessive synthesis of centrosomes through the increase in the expression of PLK4, which is a transcriptional target of E2F1. On the other
Yair Alfaro-Mora +7 more
doaj +1 more source
Effects of cell cycle noise on excitable gene circuits [PDF]
, 2016 We assess the impact of cell cycle noise on gene circuit dynamics. For bistable genetic switches and excitable circuits, we find that transitions between metastable states most likely occur just after cell division and that this concentration effect ...
Bennett, Matthew R. +4 more
core +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Cell DivisionBackground Overexpression or downregulation of long noncoding RNA (lncRNA) plays an essential role in the progression and chemotherapy-resistant of breast cancer (BRCA). LncPRESS1 is a lncRNA regulated by p53, suggesting its potential in participating in
Longzhu Ke +7 more
doaj +1 more source