Results 51 to 60 of about 7,903,122 (310)

LncPRESS1 promotes the progression and cisplatin resistance of breast cancer through upregulation of ENO1 and activation of glycolysis

Cell Division
Background Overexpression or downregulation of long noncoding RNA (lncRNA) plays an essential role in the progression and chemotherapy-resistant of breast cancer (BRCA). LncPRESS1 is a lncRNA regulated by p53, suggesting its potential in participating in
Longzhu Ke, Wei Gao, Yuanxiu Leng, Jie Chen, Hong Chen, Shangshang Li, Yingwen Zhang, Li Luo   +7 more
doaj   +1 more source

Measuring DNA content in live cells by fluorescence microscopy

Cell Division, 2018
Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associated ...
Cecil J. Gomes, Michael W. Harman, Sara M. Centuori, Charles W. Wolgemuth, Jesse D. Martinez   +4 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Molecular pathology of microRNA-339 during tumor progression

Cell Division
Cancer, as one of the main causes of human deaths, has an adverse effect on the quality of life in cancer patients. Despite many advances in diagnostic and therapeutic methods, there is still a poor prognosis in cancer patients that can be associated ...
Iman Akhlaghipour, Negin Taghehchian, Meysam Moghbeli   +2 more
doaj   +1 more source

Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells

Cell Division, 2023
Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients. A wide range
Amirhosein Maharati, Meysam Moghbeli
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Identification of transcriptional and metabolic programs related to mammalian cell size [PDF]

, 2014
Background Regulation of cell size requires coordination of growth and proliferation. Conditional loss of cyclin-dependent kinase 1 in mice permits hepatocyte growth without cell division, allowing us to study cell size in vivo using transcriptomics and ...
Mlettinen, Teemu P., Pessa, Heli K. J., Bjoerklund, Mikael, Diril, M. Kasim, Sauer, Uwe; id_orcid, Fuhrer, Tobias, Kaldis, Philipp, Sauer, Uwe, Bjorklund, Mikael, DİRİL, MUHAMMED KASIM, Caldez, Matias J., Miettinen, Teemu P., Miettinen TP, Sauer U, Björklund M, Fuhrer T, Pessa HK, Diril MK, Caldez MJ, Kaldis P, Pessa, Heli K.J.   +20 more
core   +1 more source

CRY arrests Cop1 to regulate circadian rhythms in mammals

Cell Division, 2019
Cryptochromes (CRYs) are UVA and blue light photoreceptors present in all major evolutionary lineages ranging from cyanobacteria to plants and animals, including mammals. In plants, blue light activates CRYs to induce photomorphogenesis by inhibiting the
Choogon Lee
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

In vivo analysis of cell division during vertebrate development [PDF]

, 2009
textIn this work, we identified and characterized developmentally regulated aspects to cell division in the Xenopus laevis. We found that cells in the early neural plate divide in an oriented manner.
Kieserman, Esther Kathleen
core