Results 51 to 60 of about 15,182,492 (337)

Measuring DNA content in live cells by fluorescence microscopy

Cell Division, 2018
Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associated ...
Cecil J. Gomes, Michael W. Harman, Sara M. Centuori, Charles W. Wolgemuth, Jesse D. Martinez   +4 more
doaj   +1 more source

Deterministic and stochastic descriptions of gene expression dynamics

, 2012
A key goal of systems biology is the predictive mathematical description of gene regulatory circuits. Different approaches are used such as deterministic and stochastic models, models that describe cell growth and division explicitly or implicitly etc ...
A.M. Walczak, C. Tan, C.V. Rao, D.L. Cook, David Gomez, E. Andrianantoandro, E.M. Ozbudak, H. Bremer, H.H. McAdams, I. Golding, J. Hasty, J. Hasty, J. Paulsson, J. Paulsson, J. Peccoud, J. Yu, J.A. Bernstein, J.L. Spudich, K. Nath, L. Bintu, L. Cai, M. Kaern, M. Scott, M. Scott, M. Thattai, M.B. Elowitz, M.E. Csete, M.E. Wall, M.S. Ko, N. Brenner, N. Mitarai, N.A. Cookson, N.J. Guido, O.G. Berg, O.G. Berg, P. Guptasarma, P. Wang, P.S. Swain, R. Kwok, Rahul Marathe, S. Cooper, S. Cooper, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Klumpp, S. Reeh, Stefan Klumpp, U. Alon, Veronika Bierbaum, Y. Taniguchi   +51 more
core   +1 more source

Modelling protein localisation and positional information in subcellular systems [PDF]

, 2008
Cells and their component structures are highly organised. The correct function of many biological systems relies upon not only temporal control of protein levels but also spatial control of protein localisation within cells.
Tostevin, Filipe John, Tostevin, Filipe John   +1 more
core   +1 more source

Real‐World Pediatric Blinatumomab Administration: Access to Outpatient Care Delivery and Impact of a Hospital‐Dispensed Model

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab has been shown to be highly effective for patients with pediatric B‐ALL and has recently become standard of care therapy. Due to its past use in the clinical trial setting, there is limited information available about real‐world administration.
Katelyn Oranges, Kelly A. Duffy, Sara McDonough, Evelyn Kurpiewski, R. Jennifer Randall, Allison Barz Leahy, Haley M. Newman, Joyce P. Lee, Stephen P. Hunger, Anne F. Reilly, David T. Teachey, Susan R. Rheingold, Daniel J. Zheng   +12 more
wiley   +1 more source

Molecular pathology of microRNA-339 during tumor progression

Cell Division
Cancer, as one of the main causes of human deaths, has an adverse effect on the quality of life in cancer patients. Despite many advances in diagnostic and therapeutic methods, there is still a poor prognosis in cancer patients that can be associated ...
Iman Akhlaghipour, Negin Taghehchian, Meysam Moghbeli   +2 more
doaj   +1 more source

Role of microRNAs in regulation of doxorubicin and paclitaxel responses in lung tumor cells

Cell Division, 2023
Lung cancer as the leading cause of cancer related mortality is always one of the main global health challenges. Despite the recent progresses in therapeutic methods, the mortality rate is still significantly high among lung cancer patients. A wide range
Amirhosein Maharati, Meysam Moghbeli
doaj   +1 more source

ZipN is an essential FtsZ membrane tether and contributes to the septal localization of SepJ in the flamentous cyanobacterium Anabaena [PDF]

, 2019
The organismic unit of heterocyst-forming cyanobacteria is a filament of communicating cells connected by septal junctions, proteinaceous structures bridging the cytoplasms of contiguous cells.
Arévalo, Sergio, Camargo Bernal, Sergio, Corrales Guerrero, Laura, Herrero Moreno, Antonia, Picossi Goñi, Silvia María, Valladares Ruiz, Ana   +5 more
core   +2 more sources

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

CRY arrests Cop1 to regulate circadian rhythms in mammals

Cell Division, 2019
Cryptochromes (CRYs) are UVA and blue light photoreceptors present in all major evolutionary lineages ranging from cyanobacteria to plants and animals, including mammals. In plants, blue light activates CRYs to induce photomorphogenesis by inhibiting the
Choogon Lee
doaj   +1 more source

Single-cell spatial reconstruction reveals global division of labor in the mammalian liver

Nature, 2016
The mammalian liver consists of hexagon-shaped lobules that are radially polarized by blood flow and morphogens. Key liver genes have been shown to be differentially expressed along the lobule axis, a phenomenon termed zonation, but a detailed genome ...
K. B. Halpern, Rom Shenhav, Orit Matcovitch-Natan, Beáta Tóth, D. Lemze, Matan Golan, Efi E. Massasa, Shaked Baydatch, S. Landen, A. Moor, A. Brandis, A. Giladi, Avigail Stokar Avihail, Eyal David, I. Amit, S. Itzkovitz   +15 more
semanticscholar   +1 more source