Results 61 to 70 of about 7,903,122 (310)

A mosaic genetic screen for novel mutations affecting Drosophila neuroblast divisions [PDF]

, 2006
Background: The asymmetric segregation of determinants during cell division is a fundamental mechanism for generating cell fate diversity during development.
Slack Cathy, W Somers, Sousa-Nunes, Rita, Chia, W., Chia William, Cathy Slack, Chia, W, Slack, C, Somers W, Sousa-Nunes, R., Somers, W. Gregory, Paul M Overton, Somers, W G, Slack, Cathy, Overton Paul M, Rita Sousa-Nunes, Overton, P M, William Chia, Sousa-Nunes Rita, Slack, C., Overton, Paul M., Somers, W.G., Overton, P.M., Chia, William, Sousa-Nunes, Rita; id_orcid   +24 more
core   +1 more source

Preventing DNA over-replication: a Cdk perspective

Cell Division, 2008
The cell cycle is tightly controlled to ensure that replication origins fire only once per cycle and that consecutive S-phases are separated by mitosis.
Porter Andrew CG
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Cell division licensing in the multi-chromosomal $Vibrio\ cholerae$ bacterium

, 2016
International audienceCell division must be coordinated with chromosome replication and segregation to ensure the faithful transmission of genetic information during proliferation.
Desfontaines, Jean-Michel, Le Bars, Romain, Yamaichi, Yoshiharu, Galli, Elisa, Barre, François-Xavier, Poidevin, Mickaël, Muresan, Leila, Paly, Evelyne   +7 more
core   +1 more source

The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation

Cell Division, 2010
The multi-functional adaptor protein NEDD9/HEF1/Cas-L regulates cell motility, invasion and cell cycle progression, and plays key roles in cancer progression and metastasis.
Moore Finola E, Osmundson Evan C, Koblinski Jennifer, Pugacheva Elena, Golemis Erica A, Ray Dipankar, Kiyokawa Hiroaki   +6 more
doaj   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Cell Division Compromises Epithelial Cell Polarity and Drives Tumor Progression

, 2021
Epithelia are the predominant tissue type of the animal body and form major components of most organs. As with all tissues, the formation of epithelia during development and their stem cell-based renewal requires cell division. This presents a problem as
Jeyanathan, Gayaanan
core  

Emerging players in the initiation of eukaryotic DNA replication

Cell Division, 2012
Faithful duplication of the genome in eukaryotes requires ordered assembly of a multi-protein complex called the pre-replicative complex (pre-RC) prior to S phase; transition to the pre-initiation complex (pre-IC) at the beginning of DNA replication ...
Shen Zhen, Prasanth Supriya G
doaj   +1 more source

Cell Polarity from Cell Division [PDF]

Developmental Cell, 2007
Apical-basal polarity of epithelial cells is critical for their symmetric versus asymmetric division and commonly thought to be established in interphase. In a novel type of cell division termed "mirror-symmetric", apical cell constituents accumulate during M-phase at the cleavage furrow, resulting in epithelial daughter cells with opposite apical ...
Knust, E., Huttner, W.
openaire   +3 more sources

Identifying Patterns of Hospitalizations Among Childhood Cancer Survivors: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood cancer survivors (CCSs) experience more hospitalizations than the general population. We aimed to identify distinct hospitalization patterns among Queensland CCSs and the associated characteristics. Methods Cases (aged ≤14 years) diagnosed between 1995 and 2019 while residents of Queensland were identified through the ...
Hai Pham, Teyl Engstrom, Peter Baade, Natalie Bradford, Sarah Pont, Louise Marquart‐Wilson, Natasha Nassar, Jason D. Pole   +7 more
wiley   +1 more source