Results 21 to 30 of about 98,967 (297)

Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity [PDF]

, 2022
Although various dual-target tubulin inhibitors have been designed and synthesised, no dual tubulin-NEDDylation inhibitors as antiproliferative agents were reported so far.
Fu, Dong-Jun, Wang, Ting, Ting Wang, Dong-Jun Fu   +3 more
core   +3 more sources

Evaluation of in vitro antiproliferative activity of new oligopyrrolidine-based compounds [PDF]

, 2023
reservedLa tesi di laurea riguarda la valutazione dell'attività antiproliferativa in vitro di nuovi composti oligopyrrolidine-based tramite varie metodiche di chemical biology applicate su un pannello di linee cellulari tumorali.The graduation thesis ...
FORNER, MATTEO
core  

Synthesis, characterization and antiproliferative activity of hexa arm star shaped thiosemicarbazones derived from cyclotriphosphazene core [PDF]

, 2014
A series of novel hexa-arm star shaped thiosemicarbazones with different substitutions at para positions emanating from cyclotriphosphazene core were prepared with excellent yields.
Patil, B.R., Machakanur, S.S., Bakale, R.P., Naik, G.N., Bligh, S.W.A., Gudasi, K.B.   +5 more
core   +1 more source

Antiproliferative Activity of Greek Propolis

Journal of Medicinal Food, 2010
The butanolic extract and the isolated chemical constituents, mainly diterpenes and flavonoids, from Greek propolis have been tested for their cytostatic activities against human malignant and normal cell strains. The extract and the diterpenes were found to be the most active against HT-29 human colon adenocarcinoma cells, without affecting normal ...
Pratsinis, H., Kletsas, D., Melliou, E., Chinou, I.   +3 more
openaire   +3 more sources

Untargeted LC-MS/MS-Based Multi-Informative Molecular Networking for Targeting the Antiproliferative Ingredients in Tetradium ruticarpum Fruit

Molecules, 2022
The fruit of Tetradium ruticarpum (TR) is commonly used in Chinese herbal medicine and it has known antiproliferative and antitumor activities, which can serve as a good source of functional ingredients.
Chun-Han Su, Yu-Chieh Cheng, Yu-Chia Chang, Ting-Hsuan Kung, Yu-Li Chen, Kuei-Hung Lai, Hsi-Lung Hsieh, Chun-Yu Chen, Tsong-Long Hwang, Yu-Liang Yang   +9 more
doaj   +1 more source

Design, Synthesis and Biological Evaluation of a New Series of 1-Aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea Derivatives as Antiproliferative Agents

Molecules, 2019
To discover new antiproliferative agents with high efficacy and selectivity, a new series of 1-aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea derivatives (7a–7t) were designed, synthesized and evaluated for their antiproliferative activity against A549,
Chuanming Zhang, Xiaoyu Tan, Jian Feng, Ning Ding, Yongpeng Li, Zhe Jin, Qingguo Meng, Xiaoping Liu, Chun Hu   +8 more
doaj   +1 more source

Antiproliferative and Trypanocidal Activity of Ivermectin Bioconjugates [PDF]

ACS Omega
Ivermectin (IVR), whose discovery has been Nobel-Prize-honored, is a 16-membered macrocyclic lactone used in medicine as an extremely effective and safe antiparasitic drug. In recent years, interest in this compound has grown due to its potential effectiveness in killing various types of cancer cells. However, research on the anticancer activity of IVR
Michał Sulik, Dagmara Otto-Ślusarczyk, Dietmar Steverding, Marta Struga, Adam Huczyński   +4 more
openaire   +3 more sources

Backbone modified TBA analogues endowed with antiproliferative activity [PDF]

, 2017
Background: Thrombin binding aptamer (TBA) is endowed with antiproliferative properties but its potential development is counteracted by concomitant anticoagulant activity. Methods: Five oligonucleotides (ODNs) based on TBA sequence (GGTTGGTGTGGTTGG) and
VELLECCO, VALENTINA, RUSSO, GIULIA, AMATO, TERESA, BUCCI, MARIAROSARIA, VIRGILIO, ANTONELLA, ESPOSITO, VERONICA, RUSSO, ANNAPINA, GALEONE, ALDO, VARRA, MICHELA   +8 more
core   +1 more source

Antioxidant and antiproliferative activity of Asparagopsis Taxiformis

Pharmacognosy Research, 2017
Asparagopsis taxiformis (Rhodophyta) is a species of red algae belonging to the family Bonnemaisoniaceae. The objective of the present study was to evaluate antioxidant and antiproliferative activity of four fractions (petroleum ether, chloroform, ethyl acetate, and methanol) of A. taxiformis.The red seaweed, A.
Neethu, P. V., Suthindhiran, K., Jayasri, M. A.   +2 more
openaire   +3 more sources

The contribution of different polyphenol compositions from chokeberry produced in China to cellular antioxidant and antiproliferative activities

Food Science and Human Wellness, 2023
Abundant polyphenols make chokeberry have beneficial antioxidant and antiproliferative activity. In order to explore the contribution of different polyphenols in chokeberry to these activities, this study was conducted to determine polyphenol composition
Ningxuan Gao, Xu Si, Wenzhong Han, Ersheng Gong, Chi Shu, Jinlong Tian, Yuehua Wang, Jiyue Zhang, Binxu Li, Bin Li   +9 more
doaj   +1 more source