Results 21 to 30 of about 98,614 (298)

Synthesis and in vitro antiproliferative and antibacterial activity of new thiazolidine-2,4-dione derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
In our present research, we synthesised new thiazolidine-2,4-diones (12–28). All the newly synthesised compounds were evaluated for antiproliferative and antibacterial activity.
Nazar Trotsko, Agata Przekora, Justyna Zalewska, Grażyna Ginalska, Agata Paneth, Monika Wujec   +5 more
doaj   +2 more sources

Copper Ion Attenuated the Antiproliferative Activity of Di-2-pyridylhydrazone Dithiocarbamate Derivative; However, There Was a Lack of Correlation between ROS Generation and Antiproliferative Activity

Molecules, 2016
The use of chelators for cancer treatment has been an alternative option. Dithiocarbamates have recently attracted considerable attention owning to their diverse biological activities; thus, the preparation of new dithiocarbamate derivatives with ...
Tingting Wang, Yun Fu, Tengfei Huang, Youxun Liu, Meihao Wu, Yanbin Yuan, Shaoshan Li, Changzheng Li   +7 more
doaj   +2 more sources

Biological Activity Survey of Pereskia aculeata Mill. and Pereskia grandifolia Haw. (Cactaceae) [PDF]

Pharmaceutical Sciences, 2022
Background: Pereskia aculeata and P. grandifolia are non-traditional Brazilian vegetables with high nutritional value used in traditional medicine.
Adriana Muniz Massocatto, Nyéssia Fernanda de Souza Silva, Caroline Calixto Kazama, Michele Dal Bem Pires, Orlando Seiko Takemura, Ezilda Jacomassi, Ana Lúcia Tasca Gois Ruiz, Antonio Laverde Junior   +7 more
doaj   +1 more source

Antiproliferative and apoptosis-inducing properties of selected medicinal plants of Assam, India

Archives of Medicine and Health Sciences, 2021
Background and Aim: Ethnomedicine is a common practice of disease treatment among tribal communities of India. The present study investigated the antiproliferative and apoptosis-inducing activities of seven medicinal plants traditionally used by the Bodo
Mritunjoy Kumar Roy, Ananta Swargiary, Akalesh Kumar Verma   +2 more
doaj   +1 more source

In vitro antiproliferative and antioxidant activity of three fungal strains from the White sea

, 2021
Fungi have been recognized as a prolific source of bioactive compounds with a wide spectrum of bioactivities, nevertheless, the information about marine polar fungi is scarce.
Alla V. Shnyreva, Shnyreva, Alla V., Couttolenc, Alan, Albina I. Sergeeva, Alan Couttolenc, Kurakov, Alexander V., Sergeeva, Albina I., Trigos, Ángel, Ángel Trigos, Alexander V. Kurakov, José M. Padrón, Padrón, José M.   +11 more
core   +1 more source

The cancer preventive activity and mechanisms of prenylated resveratrol and derivatives

Current Research in Toxicology, 2023
Resveratrol is regarded as neutraceuticals with multiple health benefits. The introduction of prenyl can enhance the bioactivity. In this work, the cancer preventive activities and mechanisms of 18 prenylated reseveratrol and derivatives were ...
Ting Zhou, Yueming Jiang, Bin Zeng, Bao Yang   +3 more
doaj   +1 more source

Antiproliferative and Antimicrobial Activities of Selected Bryophytes [PDF]

Molecules, 2018
One-hundred and sixty-eight aqueous and organic extracts of 42 selected bryophyte species were screened in vitro for antiproliferative activity on a panel of human gynecological cancer cell lines containing HeLa (cervix epithelial adenocarcinoma), A2780 (ovarian carcinoma), and T47D (invasive ductal breast carcinoma) cells using the 3-(4,5 ...
Martin Vollár, András Gyovai, Péter Szűcs, István Zupkó, Marianna Marschall, Boglárka Csupor-Löffler, Péter Bérdi, Anikó Vecsernyés, Attila Csorba, Erika Liktor-Busa, Edit Urbán, Dezső Csupor   +11 more
openaire   +5 more sources

Development of Novel Erythromycin Derivatives with Inhibitory Activity against Proliferation of Tumor Cells. [PDF]

PLoS ONE, 2016
In our continuing structure-activity relationship study of a new class of erythromycin A (EM-A) derivatives with antiproliferative activity, a new series of de(N-methyl) EM-A dimers jointed by a four-atom linker, -CH2CH = CHCH2-, were prepared and their ...
Lan Wu, Kai Bao, Rui Song, Defa Wang, Lei Zhang, Weiyun Wang, Weige Zhang, Wen Bin   +7 more
doaj   +1 more source

Lipophilic modification of Salirasib modulate the antiproliferative and antimigratory activity.

, 2023
Salirasib, or farnesylthiosalicylic acid (FTS), is a salicylic acid derivative with demonstrated antineoplastic activity. While designed as a competitor of the substrate S-farnesyl cysteine on Ras, it is a potent competitive inhibitor of ...
Exequiel O. J., Porta, Carla M. , Borini Etichetti, José M., Padrón, María Sol, Ballari, Javier, Girardini, Guillermo R., Labadie, Evelyn , Arel Zalazar   +6 more
core   +1 more source

ANTIPROLIFERATIVE ACTIVITY OF BERBERINE IN VITRO AND IN VIVO [PDF]

Biomedical Papers, 2005
Berberine, an isoquinoline plant alkaloid acted cytotoxically in vitro on tumour cell lines B16. Its anticancer activity in vivo was studied with the transplanted B16 line in the range of doses from 1 mg/kg to 10 mg/kg. The significant reduction of tumor volume was observed on day 16 at doses of 5 and 10 mg/kg.
Silvia, Letasiová, Sona, Jantová, Marta, Múcková, Marica, Theiszová   +3 more
openaire   +2 more sources