Results 1 to 10 of about 360,716 (266)
Scientific Reports, 2022 Stimulation of hair growth in hair loss has been a difficult goal to achieve. Hair follicle-associated pluripotent (HAP) stem cells express nestin and have been shown to differentiate to multiple cell types including keratinocytes, neurons, beating ...
Koya Obara +7 more
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An Open Access Database of Licensed Cancer Drugs
Frontiers in Pharmacology, 2021 A global, comprehensive and open access listing of approved anticancer drugs does not currently exist. Partial information is available from multiple sources, including regulatory authorities, national formularies and scientific agencies.
Pan Pantziarka +5 more
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Scientific Reports, 2021 In order to identify more effective therapy for recalcitrant osteosarcoma, we evaluated the efficacy of an mTOR-VEGFR inhibitor combination on tumor growth in a unique osteosarcoma patient-derived orthotopic xenograft (PDOX) mouse model derived from the ...
Hiromichi Oshiro +7 more
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Molecules, 2022 Cancer is a multifactorial disorder caused by several aberrations in gene expression that generate a homeostatic imbalance between cell division and death [...]
Alessandra Ammazzalorso +1 more
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American Journal of Clinical Pathology, 2003 The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impact on nonmalignant bystander organs
Jeffrey S, Ross +4 more
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Cells, 2019 An excessive requirement for methionine (MET), termed MET dependence, appears to be a general metabolic defect in cancer and has been shown to be a very effective therapeutic target. MET restriction (MR) has inhibited the growth of all major cancer types
Kei Kawaguchi +7 more
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Cells, 2019 We developed tumor-targeting Salmonella typhimurium (S. typhimurium) A1-R, a facultative anaerobe that is an auxotroph of leucine and arginine. The tumor-targeting efficacy of S. typhimurium A1-R was demonstrated in vivo and vitro using several malignant
Takashi Murakami +6 more
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Sesterterpenoids with Anticancer Activity [PDF]
Current Medicinal Chemistry, 2015 Terpenes have received a great deal of attention in the scientific literature due to complex, synthetically challenging structures and diverse biological activities associated with this class of natural products. Based on the number of C5 isoprene units they are generated from, terpenes are classified as hemi- (C5), mono- (C10), sesqui- (C15), di- (C20)
EVIDENTE, ANTONIO +7 more
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BMC Cancer, 2018 Background Pleomorphic liposarcoma (PLPS) is a rare, heterogeneous and an aggressive variant of liposarcoma. Therefore, individualized therapy is urgently needed.
Tasuku Kiyuna +16 more
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Incidental Parathyroidectomy during Total Thyroidectomy: Risk Factors and Consequences
International Journal of Endocrinology, 2016 Objective. To evaluate the incidence of accidental parathyroidectomy in our series of total thyroidectomies, to investigate its clinical and biochemical consequences, and to identify potential risk factors. Methods.
Dimitrios K. Manatakis +5 more
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