Results 41 to 50 of about 487,301 (268)
Isolated pancreatic metastasis from Merkel cell carcinoma: a case report
Journal of Rare DiseasesMerkel cell carcinoma (MCC) is a rare type of skin cancer. It is an aggressive neuroendocrine carcinoma with a high tendency for local recurrence, lymphatic and distant metastasis.
Maria Igoumenidi +6 more
doaj +1 more source
The development of an anti-cancer peptide M1-21 targeting transcription factor FOXM1
Cell & Bioscience, 2023 Background Transcription factor FOXM1 is a potential target for anti-cancer drug development. An interfering peptide M1-21, targeting FOXM1 and FOXM1-interacting proteins, is developed and its anti-cancer efficacy is evaluated.
Haojie Cheng +9 more
doaj +1 more source
Coupling dichloroacetate treatment with curcumin significantly enhances anticancer potential
, 2018 [[abstract]]BACKGROUND/AIM: Dichloroacetate (DCA) and curcumin have been shown to be potent drug candidates in cancer therapy. Our study aimed to investigate the combined effects of DCA and essential oil-blended curcumin (ECUR) using the hepatoma Huh-7 ...
Kan, PC;Chang, YJ;Chien, CS;Su, CY;Fang, HW
core +1 more source
Metal complexes as DNA intercalators [PDF]
, 2011 DNA has a strong affinity for many heterocyclic aromatic dyes, such as acridine and its derivatives. Lerman in 1961 first proposed intercalation as the source of this affinity, and this mode of DNA binding has since attracted considerable research ...
Peter J. Sadler +3 more
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
ΔIK17: An Antigen Expressed on Human Lymphocytes
The International Journal of Biological Markers, 1996 Anti-ΔIK17 monoclonal antibody was produced by fusing SP2/0/Ag14 myeloma with spleen cells of BALB/c mice immunized with normal human thymocytes. AΔIK17 antibody recognizes a 44kD cell surface protein detected on human lymphocytes.
R. Sotiriadou +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
The Immunohistochemical Expression MTA 1 Protein and its Prognostic Value in Pancreatic Cancer
Journal of Investigative Surgery, 2018 Purpose/aim: To examine with immunohistochemical assay MTA1 protein expression levels in pancreatic cancer tissues defining its prognostic value. Material and Methods: The specimens derived from 51 patients who underwent surgery.
Efstathios T. Pavlidis +8 more
doaj +1 more source
Stem Cell Research & Therapy, 2017 Background Human mesenchymal stem cells are promising tools for regenerative medicine due to their ability to differentiate into many cellular types such as osteocytes, chondrocytes and adipocytes amongst many other cell types.
Hanna Hanna +2 more
doaj +1 more source
Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion
Biomedicines, 2022 Breast cancer has a high risk of recurrence and distant metastasis after remission. Controlling distant metastasis is important for reducing breast cancer mortality, but accomplishing this goal remains elusive.
Hee Yeon Kim +6 more
doaj +1 more source