Results 21 to 30 of about 487,301 (268)

Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]

, 2012
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A., Moreno Martínez, Virtudes, Carrion-Salip, Dolors, González-Cantó, A., Massaguer, A., Sadler, Peter, Llorens Duran, Rafael de, Massaguer i Vall-llovera, Anna, González Ibañez, Carlos, Massaguer, Anna, de Llorens, Rafael, Carrion-Salip, D, González, Carlos, Gómez-Pinto, Irene, Sadler, P. J., Moreno, Virtudes, Barragán, F., Barragán, Flavia, Sadler, P.J., Llorens, Rafael de, Marchán Sancho, Vicente, Sadler, Peter J., Carrion Salip, Dolors, Marchán, Vicente, González-Cantó, Alejandro   +24 more
core   +1 more source

Expression dynamics of integrin α2, α3, and αV upon osteogenic differentiation of human mesenchymal stem cells

Stem Cell Research & Therapy, 2020
Background The differentiation of human mesenchymal stem cells (hMSCs) into osteoblasts (OBs) is a prerequisite for bone formation. However, little is known about the definitive surface markers for OBs during osteogenesis.
Hyun Min Lee, Se-Ri Seo, Jeeseung Kim, Min Kyu Kim, Hyosun Seo, Kyoung Soo Kim, Young-Joo Jang, Chun Jeih Ryu   +7 more
doaj   +1 more source

CD1d-independent NK1.1+ Treg cells are IL2-inducible Foxp3+ T cells co-expressing immunosuppressive and cytotoxic molecules

Frontiers in Immunology, 2022
Regulatory T cells (Treg) play pivotal roles in maintaining self-tolerance and preventing immunological diseases such as allergy and autoimmunity through their immunosuppressive properties.
Hyun Jung Park, Sung Won Lee, Yun Hoo Park, Tae-Cheol Kim, Luc Van Kaer, Seokmann Hong   +5 more
doaj   +1 more source

Enhanced Tumoricidal Immune Responses by Transarterial Chemotherapy Using Novel Nanocomplexes in a Rat Liver Cancer Model

, 2022
© 2022 Anticancer Research. All rights reserved.Background/Aim: Locoregional treatments for hepatocellular carcinoma (HCC) induce immunogenic cell death and a tumor-specific immune response, but infiltration and activation of immune cells in the liver ...
Sung, Pil Soo, Tak, Eunyoung, Jin, Long, Yoon, Seung Kew, Kang, Byung-Yoon, Chun, Ho Jong, Hur, Wonhee, Kim, Sung Min, Han, Ji Won, Kim, Won Jong, Roh, Pu Reun   +10 more
core   +1 more source

Incidental Parathyroidectomy during Total Thyroidectomy: Risk Factors and Consequences

International Journal of Endocrinology, 2016
Objective. To evaluate the incidence of accidental parathyroidectomy in our series of total thyroidectomies, to investigate its clinical and biochemical consequences, and to identify potential risk factors. Methods.
Dimitrios K. Manatakis, Dimitrios Balalis, Vasiliki N. Soulou, Dimitrios P. Korkolis, Georgios Plataniotis, Emmanouil Gontikakis   +5 more
doaj   +1 more source

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model

BMC Cancer, 2018
Background Pleomorphic liposarcoma (PLPS) is a rare, heterogeneous and an aggressive variant of liposarcoma. Therefore, individualized therapy is urgently needed.
Tasuku Kiyuna, Yasunori Tome, Takashi Murakami, Kei Kawaguchi, Kentaro Igarashi, Kentaro Miyake, Masuyo Miyake, Yunfeng Li, Scott D. Nelson, Sarah M. Dry, Arun S. Singh, Tara A. Russell, Irmina Elliott, Shree Ram Singh, Fuminori Kanaya, Fritz C. Eilber, Robert M. Hoffman   +16 more
doaj   +1 more source

Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]

, 2013
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Hands-Portman, Ian, Liu, Zhe, Sadler, P. J., Hearn, Jessica M., Qamar, Bushra, Romero-Canelón, Isolda   +5 more
core   +1 more source

ΔIK17 Antigen: A Possible Early Marker of Cancer Development

The International Journal of Biological Markers, 1996
ΔIK17 is a 44 kD molecule located on the surface of T, B and NK cells in normal peripheral blood mononuclear cells (PBMC) (1). The portion of PBMC expressing ΔIK17 was determined in 52 patients with benign breast diseases, 182 patients with breast ...
S. Perez, R. Sotiriadou, G. Missitzis, T. Trangas, N. Giannoulis, D. Mavroudeas, N. Apostolikas, D. Kokkinopoulos   +7 more
doaj   +1 more source

The recurrent laryngeal nerve and extralaryngeal branches in relation to the inferior thyroid artery, Berry’s ligament, tracheal groove, and Zuckerkandl tubercle: an experience of 60 thyroidectomies [PDF]

Folia Medica
Aim: The aim of this study was to examine the anatomical variations of the inferior laryngeal nerve compared with its extralaryngeal branches, the inferior thyroid artery, Berry’s ligament, the tracheal groove, and the tubercle of Zuckerkandl, as ...
Zoi Nitsa, Marianna Mpolianidou, Stelios Faltsetas, Michael Katsamakas   +3 more
doaj   +3 more sources

Identification of an Immune Gene Signature Based on Tumor Microenvironment Characteristics in Colon Adenocarcinoma

Cell Transplantation, 2021
Tumor microenvironment (TME) changes are related to the occurrence and development of colon adenocarcinoma (COAD). This study aimed to analyze the characteristics of the immune microenvironment in CC, as well as the microenvironment’s relationship with ...
Ying Chen, Jia Zhao
doaj   +1 more source