Results 11 to 20 of about 552,206 (313)
Molecules, 2022 Cancer is a multifactorial disorder caused by several aberrations in gene expression that generate a homeostatic imbalance between cell division and death [...]
Alessandra Ammazzalorso +1 more
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American Journal of Clinical Pathology, 2003 The recent clinical and commercial success of anticancer antibodies such as rituximab and trastuzumab has created great interest in antibody-based therapeutics for hematopoietic malignant neoplasms and solid tumors. Given the likelihood of lower toxic effects of antibodies that target tumor cells and have limited impact on nonmalignant bystander organs
Jeffrey S, Ross +4 more
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The universe of normal and cancer cell line responses to anticancer treatment: Lessons for cancer therapy [PDF]
, 2011 According to the Surveillance Epidemiology and End Results report, 1,479,350 men and women will be diagnosed with and 562,340 will die of cancer of all sites in 2009, indicating that about 40% of the cancer patients do not respond well to current ...
Alexei Vazquez
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Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]
, 2009 This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Rijt, Sabine H. van, Sadler, P. J.
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Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]
, 2011 Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van +7 more
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Combination chemotherapy with anticancer agents and OK-432 [PDF]
, 1974 Antitumor effects of the combination chemotherapy with hemolytic streptococcus preparation, OK-432, and various anticancer agents were observed on experimental tumors and human cancers.
Sugiyama, Motoharu +6 more
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Organometallic half-sandwich iridium anticancer complexes [PDF]
, 2011 The low-spin 5d6 IrIII organometallic half-sandwich complexes [(η5-Cpx)Ir(XY)Cl]0/+, Cpx = Cp*, tetramethyl(phenyl)cyclopentadienyl (Cpxph), or tetramethyl(biphenyl)cyclopentadienyl (Cpxbiph), XY = 1,10-phenanthroline (4−6), 2,2′-bipyridine (7−9 ...
Liu, Zhe +34 more
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PPARs and Anticancer Therapies [PDF]
PPAR Research, 2010 Welcome to this special issue of PPAR research, PPARs, and anticancer therapies. Peroxisomal proliferator-activated receptor (PPAR) α, δ, and γ are members of the nuclear hormone receptor superfamily of ligand-activated transcription factors first identified some 20 years ago.
Robbins, M.E.C. +2 more
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Unusual DNA binding modes for metal anticancer complexes [PDF]
, 2009 DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
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, 2022 © 2022 Anticancer Research. All rights reserved.Background/Aim: Locoregional treatments for hepatocellular carcinoma (HCC) induce immunogenic cell death and a tumor-specific immune response, but infiltration and activation of immune cells in the liver ...
Sung, Pil Soo +21 more
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