Characterization of the Hemolytic Activity of Mastoparan Family Peptides from Wasp Venoms [PDF]
Toxins, 2023 Biologically active peptides have attracted increasing attention in research on the development of new drugs. Mastoparans, a group of wasp venom linear cationic α-helical peptides, have a variety of biological effects, including mast cell degranulation ...
Xiangdong Ye +10 more
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Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis [PDF]
Veterinary Research, 2021 Riemerella anatipestifer causes epizootic infectious disease in poultry resulting in serious economic losses especially to the duck industry. In our previous study, R. anatipestifer was found to lyse duck erythrocytes in vitro.
Bingqing Sun +9 more
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Peptide hemolytic activity analysis using visual data mining of similarity-based complex networks [PDF]
npj Systems Biology and ApplicationsPeptides are promising drug development frameworks that have been hindered by intrinsic undesired properties including hemolytic activity. We aim to get a better insight into the chemical space of hemolytic peptides using a novel approach based on ...
Kevin Castillo-Mendieta +7 more
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Impact of the Hydrolysis and Methanolysis of Bidesmosidic Chenopodium quinoa Saponins on Their Hemolytic Activity [PDF]
Molecules, 2022 Saponins are specific metabolites abundantly present in plants and several marine animals. Their high cytotoxicity is associated with their membranolytic properties, i.e., their propensity to disrupt cell membranes upon incorporation.
Philippe Savarino +5 more
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Bacillus velezensis iturins inhibit the hemolytic activity of Staphylococcus aureus [PDF]
Scientific ReportsBovine mastitis caused by S. aureus has a major economic impact on the dairy sector. With the crucial need for new therapies, anti-virulence strategies have gained attention as alternatives to antibiotics.
Yasmin Neves Vieira Sabino +9 more
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Cationicity Enhancement on the Hydrophilic Face of Ctriporin Significantly Reduces Its Hemolytic Activity and Improves the Antimicrobial Activity against Antibiotic-Resistant ESKAPE Pathogens [PDF]
ToxinsThe ESKAPE pathogen-associated antimicrobial resistance is a global public health issue, and novel therapeutic strategies are urgently needed. The short cationic antimicrobial peptide (AMP) family represents an important subfamily of scorpion-derived ...
Xudong Luo +6 more
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Antibacterial and Hemolytic Activity of Crotalus triseriatus and Crotalus ravus Venom [PDF]
Animals, 2020 Rattlesnakes have venoms with a complex toxin mixture comprised of polypeptides and proteins. Previous studies have shown that some of these polypeptides are of high value for the development of new medical treatments.
Adrian Zaragoza-Bastida +8 more
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Scaffold based on castor oil as an osteoconductive matrix in bone repair: biocompatibility analysis
Polímeros, 2022 To analyze the biocompatibility of the scaffold produced from a natural polymer derived from castor oil through hemolytic activity and antimicrobial activity, to enable the clinical application.
Fabianne Soares Lima +9 more
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Biotechnology Reports, 2021 This study purified a hemagglutinating protein (MoL) from Moringa oleifera seed, and investigated its hemolytic activity. Molecular weight and stability of MoL were also determined.
Tolulope Nubi +4 more
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AN ADENOSINETRIPHOSPHATE-ACTIVATED HEMOLYTIC SYSTEM [PDF]
The Journal of General Physiology, 1956 1. Hemolyzed rabbit cells contain a factor which lyses human erythrocytes in vitro when Mg++ and certain nucleotides are supplied to the system. Of the nucleotides tested ATP is the most active, although no net loss of ATP or of labile phosphate seems to be associated with the hemolytic process. 2.
B A, BOREK, M, BOVARNICK
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