Characterization of the Hemolytic Activity of Mastoparan Family Peptides from Wasp Venoms [PDF]
Toxins, 2023 Biologically active peptides have attracted increasing attention in research on the development of new drugs. Mastoparans, a group of wasp venom linear cationic α-helical peptides, have a variety of biological effects, including mast cell degranulation ...
Xiangdong Ye +10 more
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Hemolytic Activity of Nanoparticles as a Marker of Their Hemocompatibility. [PDF]
Micromachines (Basel), 2022 The potential use of nanomaterials in medicine offers opportunities for novel therapeutic approaches to treating complex disorders. For that reason, a new branch of science, named nanotoxicology, which aims to study the dangerous effects of nanomaterials on human health and on the environment, has recently emerged.
Yedgar S, Barshtein G, Gural A.
europepmc +5 more sources
Identification of genetic determinants of hemolytic activity of Riemerella anatipestifer using random transposon mutagenesis [PDF]
Veterinary Research, 2021 Riemerella anatipestifer causes epizootic infectious disease in poultry resulting in serious economic losses especially to the duck industry. In our previous study, R. anatipestifer was found to lyse duck erythrocytes in vitro.
Bingqing Sun +9 more
doaj +2 more sources
Hemolytic activity of Borrelia burgdorferi [PDF]
Infection and Immunity, 1992 Zones of beta-hemolysis occurred around colonies of Borrelia burgdorferi grown on Barbour-Stoenner-Kelly medium containing agarose and horse blood. Blood plates were inoculated with either the infective strain Sh-2-82 or noninfective strain B-31 in an overlay and incubated in a candle jar. Both strains of B. burgdorferi displayed beta-hemolysis after 1
Lisa Williams, F E Austin
openalex +3 more sources
Peptide hemolytic activity analysis using visual data mining of similarity-based complex networks [PDF]
npj Systems Biology and ApplicationsPeptides are promising drug development frameworks that have been hindered by intrinsic undesired properties including hemolytic activity. We aim to get a better insight into the chemical space of hemolytic peptides using a novel approach based on ...
Kevin Castillo-Mendieta +7 more
doaj +2 more sources
Impact of the Hydrolysis and Methanolysis of Bidesmosidic Chenopodium quinoa Saponins on Their Hemolytic Activity [PDF]
Molecules, 2022 Saponins are specific metabolites abundantly present in plants and several marine animals. Their high cytotoxicity is associated with their membranolytic properties, i.e., their propensity to disrupt cell membranes upon incorporation.
Philippe Savarino +5 more
doaj +2 more sources
Bacillus velezensis iturins inhibit the hemolytic activity of Staphylococcus aureus [PDF]
Scientific ReportsBovine mastitis caused by S. aureus has a major economic impact on the dairy sector. With the crucial need for new therapies, anti-virulence strategies have gained attention as alternatives to antibiotics.
Yasmin Neves Vieira Sabino +9 more
doaj +2 more sources
Characterization of the hemolytic activity of Riemerella anatipestifer. [PDF]
Microbiology (Reading), 2020 Riemerella anatipestifer infection causes serious economic losses in the duck industry worldwide. Acute septicemia and high blood bacterial loading in R. anatipestifer
Gong Y +9 more
europepmc +3 more sources
Journal of Biological ResearchHemolytic activity assessment is a widely used method to evaluate the toxicity of marine organisms, including jellyfish. However, there are some challenges associated with testing hemolytic activity.
Yongfang Wang +7 more
doaj +3 more sources
Cationicity Enhancement on the Hydrophilic Face of Ctriporin Significantly Reduces Its Hemolytic Activity and Improves the Antimicrobial Activity against Antibiotic-Resistant ESKAPE Pathogens [PDF]
ToxinsThe ESKAPE pathogen-associated antimicrobial resistance is a global public health issue, and novel therapeutic strategies are urgently needed. The short cationic antimicrobial peptide (AMP) family represents an important subfamily of scorpion-derived ...
Xudong Luo +6 more
doaj +2 more sources