Results 41 to 50 of about 6,154,219 (251)

Sigma E regulators control hemolytic activity and virulence in a shrimp pathogenic Vibrio harveyi. [PDF]

PLoS ONE, 2012
Members of the genus Vibrio are important marine and aquaculture pathogens. Hemolytic activity has been identified as a virulence factor in many pathogenic vibrios including V. cholerae, V. parahaemolyticus, V. alginolyticus, V. harveyi and V. vulnificus.
Pimonsri Rattanama, Janelle R Thompson, Natthawan Kongkerd, Kanchana Srinitiwarawong, Varaporn Vuddhakul, John J Mekalanos   +5 more
doaj   +1 more source

Serum hemolytic activity in healthy subjects and SSc patients.

, 2015
Serum hemolytic activity in healthy subjects and SSc patients.
Paola Caramaschi (214562), Patrizia Guarini (42983), Sara Ugolini (690338), T. Sakari Jokiranta (690339), Oscar Bortolami (19461), Serena Pedron (295544), Lucia De Franceschi (184533), Fabio Benedetti (243799), Viviana Ravagnani (146663), Fabio Poli (243797), Marco Sorio (243802), Domenico Biasi (146691), Valentina La Verde (243791), Chiara Colato (690340), Guido Martignoni (295553), Cinzia Scambi (243788)   +15 more
core   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Anti-hemolytic, antibacterial and anti-cancer activities of methanolic extracts from leaves and stems of Polygonum odoratum

Asian Pacific Journal of Tropical Biomedicine, 2018
Objective: To investigate anti-hemolytic, antibacterial and anti-cancer activities of leaf and stem extracts from Polygonum odoratum. Methods: Leaves and stems of Polygonum odoratum were extracted using methanol and their anti-hemolytic activity was ...
Nittaya Chansiw, Narisara Paradee, Kamonnaree Chotinantakul, Somdet Srichairattanakool   +3 more
doaj   +1 more source

Nutrient Alteration Drives the Impacts of Seawater Acidification on the Bloom-Forming Dinoflagellate Karenia mikimotoi

Frontiers in Plant Science, 2021
Seawater acidification and nutrient alteration are two dominant environmental factors in coastal environments that influence the dynamics and succession of marine microalgae. However, the impacts of their combination have seldom been recorded.
Qian Liu, Qian Liu, Yanqun Wang, Yuanyuan Li, Yijun Li, You Wang, You Wang, Bin Zhou, Bin Zhou, Zhongyuan Zhou, Zhongyuan Zhou   +10 more
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Toxicity and hemolytic activity predictions of designed peptides in different models using the SVM method.

, 2023
Toxicity and hemolytic activity predictions of designed peptides in different models using the SVM method.
Min-Ho Jeong (16469254), Myeong-Eun Jegal (16469245), Min Jung Park (16469242), Jaeyoung Kim (2891579), Ji Myung Choi (16469239), Yu-Seon Han (16469248), Srimai Vuppala (7296560), Bo Sun Joo (16469257), Joonkyung Jang (1609504), Yung-Jin Kim (16469251)   +9 more
core   +1 more source

Bacteria‐Trained, MnO2‐Armored Dendritic Cells for Immunotherapy

Advanced Materials, EarlyView.
MnO2‐armored, bacteria‐trained dendritic cells undergo tumor‐responsive mechanical and immunological transformation. The nanocoating masks immune ligands and maintains a mechanically stiff, quiescent state during circulation, while the tumor microenvironment removes the armor and restores cellular deformability and immune accessibility.
Zhao Guo, Min Ge, Zesong Ruan, Tingwang Shi, Mahyar Mahmoudi, Soohwan An, Na Kong, Yunfeng Chen, Han Lin, Wei Tao   +9 more
wiley   +1 more source