Results 61 to 70 of about 6,154,219 (251)

Anti-Legionella activity of staphylococcal hemolytic peptides

, 2011
International audienceA collection of various Staphylococci was screened for their anti-Legionella activity. Nine of the tested strains were found to secrete anti-Legionella compounds.
A. Marchand, Héchard, Y., Y. Héchard, Verdon, J., J. Verdon, S. Crapart, Marchand, A., Lacombe, C., J.M. Berjeaud, Crapart, S., Berjeaud, J. M., C. Lacombe   +11 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Investigating Hemolytic Activity of Candida Isolates with Two Different Methods

, 2009
The hemolytic activity of Candida isolates with agar and microplate methods were investigated and compared efficiency of these methods to assess relationship between hyphal formation and ...
Kaya, Tugba, Aydogan, Sibel, DOĞRUMAN AL, FUNDA, Aksakal, Nur, Kustimur, Semra, Aykan, Berna, Noral, Mohammad Y., Bolat, Sezen   +7 more
core   +2 more sources

Comparison and evaluation of the methods for measuring hemolytic activity of Stomolophus meleagris jellyfish tentacle extract

Journal of Biological Research
Hemolytic activity assessment is a widely used method to evaluate the toxicity of marine organisms, including jellyfish. However, there are some challenges associated with testing hemolytic activity.
Yongfang Wang, Yiran He, Fengling Yang, Yi Wang, Zhaoyun Peng, Liang Xiao, Marina Pozzolini, Yina Zhu   +7 more
doaj   +1 more source

Bacteriocin-like Inhibitory Activity Associated with Beta-hemolytic Strains of Streptococcus salivarius

, 1987
Seven beta-hemolytic Streptococcus salivarius isolates produced bacteriocin-like inhibitory activity in deferred antagonism tests using a set of nine indicator bacteria (I1-I 9). Five of these S.
G.R. Tompkins, J.R. Tagg
core   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Hemolytic toxin from the soft coral Sarcophyton trocheliophorum: isolation and physiological characterization

Journal of Venomous Animals and Toxins including Tropical Diseases, 2010
The unifying characteristic of cnidarians is the production of protein and polypeptide toxins. The present study describes the identification of a hemolytic toxin from the soft coral Sarcophyton trocheliophorum.
S Karthikayalu, V Rama, R Kirubagaran, R Venkatesan   +3 more
doaj  

Concerted Action of Targeted Nucleic Acid Therapeutics as Flexible, Precision and Personalized Cancer Treatment

Advanced Science, EarlyView.
Combinations of small activating RNAs and small interfering RNAs were developed as personalized precision therapies that simultaneously activate tumor suppressors and silence oncogenes according to the molecular signatures of patient tumors. This combination strategy demonstrated superior anticancer efficacy, highlighting the promise of precision ...
Jing Wu, Jiaxuan Chen, Abdechakour Elkihel, Wenjun Lan, Nicolas Fraunhoffer, Dandan Zhu, Baoping Lian, Christina Galanakou, Zhancun Bian, Xi Liu, Odile Gayet, Loic Moubri, Julie Aglietti Roques, Vikash Reebye, Nagy Habib, Xiaoxuan Liu, Nelson Dusetti, Juan Lucio Iovanna, Ling Peng   +18 more
wiley   +1 more source

Biochemical study of venom sea anemone Phymactis papillosa (Actiniidae)

Revista Peruana de Biología, 2017
In this work, the poison of Phymactis papillosa collected in Ancón bay has been studied biochemically. The venom was obtained by hypotonic shock and then lyophilized.
Antony Cuya, Enrique Escobar
doaj   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

Advanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source