Results 81 to 90 of about 5,885,878 (288)

ROS Self‐Supply Nanoplatform Based on Fenton Catalyst for Chemodynamic and Immunotherapy: Reprogramming Cold Tumor Into Hot Tumor in Cancer Treatment

Advanced Science, EarlyView.
A multifunctional HA‐conjugated nanoplatform (HA‐PGMC) integrates CuO2, glucose oxidase, and mil‐100 to enable cascade catalytic ROS generation in tumor microenvironments. This self‐supplying ROS strategy induces immunogenic cell death, reprograms “cold” tumors into “hot” ones, and synergizes with PD‐L1 blockade, achieving potent chemodynamic ...
Man Lung Lee, Jack Chun Hin Chen, Wai Wing Cheng, Kwan Yee Lau, Hiu Yee Kwan, Ngar‐Yun Ellen Poon, Hung‐Wing Li   +6 more
wiley   +1 more source

[Hemolytic activity of Mycobacterium kansasii].

Kekkaku : [Tuberculosis], 1990
Mycobacterium kansasii has a strong virulence as compared with those of "mycobacteria other than tubercle bacilli". In this study, hemolytic activities of several strains of M. kansasii were investigated. Secretion of hemolytic factor from these strains was not observed, since no hemolytic zone was found around the colonies grown on the 7H11 agar plate
openaire   +2 more sources

Activity theory: A framework for analysing intercultural academic activity [PDF]

, 2010
This article suggests that Activity Theory (AT) can be applied as a holistic framework to analyse the complex sociocultural issues that arise when academics wish to engage in collaborative activity across institutional and cultural boundaries.
Barnard, Roger, 2245
core  

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

Advanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao, Tao Yang, Rui Wang, Hui‐Da Li, Xiao‐Yu Zhang, Feng Cheng, Ying Liu, Jian‐Hua Wang, Ting Yang, Chuanbin Mao   +9 more
wiley   +1 more source

Hemolytic, antioxidant, and phospholipase A2 neutralization efficacy of Asparagus racemosus, Withania somnifera, Syzygium cumini, Psidium guajava, Basella alba, Morus indica, Morus laevigata, and Morus latifolia

Journal of Advanced Biotechnology and Experimental Therapeutics
Bangladesh is abundant in medicinal plants. The bioactive compounds in medicinal plants provide novel therapeutic opportunity of improving human health.
Farhana Afroz Joty, Md. Mahmudul Hasan, Md. Sohanur Rahman Sohan, Md. Jahangir Alam, Md. Abu Reza, Zennat Ferdousi   +5 more
doaj   +1 more source

Membrane-Pore Forming Characteristics of the Bordetella pertussis CyaA-Hemolysin Domain

Toxins, 2015
Previously, the 126-kDa Bordetella pertussis CyaA pore-forming/hemolysin (CyaA-Hly) domain was shown to retain its hemolytic activity causing lysis of susceptible erythrocytes. Here, we have succeeded in producing, at large quantity and high purity, the
Chattip Kurehong, Chalermpol Kanchanawarin, Busaba Powthongchin, Gerd Katzenmeier, Chanan Angsuthanasombat   +4 more
doaj   +1 more source

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Alteration of complement hemolytic activity in different trauma and sepsis models

, 2012
Christian Ehrnthaller,1 Umme Amara,1 Sebastian Weckbach,1 Miriam Kalbitz,1 Markus Huber-Lang,1 Soheyl Bahrami21Department of Traumatology, Hand, Plastic, and Reconstructive Surgery, Center of Surgery, University of Ulm, Germany; 2Ludwig Boltzmann ...
Huber-Lang M, Ehrnthaller C, Bahrami S, Amara U, Kalbitz M, Weckbach S   +5 more
core  

Hemolytic activity of the strains used in this study.

, 2014
aHemolytic units per mg of cell lysate supernatant protein.bHemolytic activity below the limit of detection of 20 HU/mg.cWild type strains.
Claudia Trappetti (221245), Richard M. Harvey (222006), Rodney K. Tweten (199029), James C. Paton (198315), Adrienne W. Paton (439447), Catherine E. Hughes (611958)   +5 more
core   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source