Results 101 to 110 of about 5,885,878 (288)

<em>In Vitro </em>and <em>in </em><em>Vivo</em> Antitumor Effect of Trachylobane-360, a Diterpene from<em> Xylopia langsdorffiana</em>

Molecules, 2012
Trachylobane-360 (<em>ent</em>-7α-acetoxytrachyloban-18-oic acid) was isolated from <em>Xylopia langsdorffiana</em>. Studies have shown that it has weak cytotoxic activity against tumor and non-tumor cells. This study investigated
João Carlos Lima Rodrigues Pita, Aline Lira Xavier, Tatyanna Kelvia Gomes de Sousa, Vivianne Mendes Mangueira, Josean Fechine Tavares, Robson José de Oliveira Júnior, Robson Cavalcante Veras, Hilzeth de Luna Freire Pessoa, Marcelo Sobral da Silva, Sandra Morelli, Veridiana de Melo Rodrigues Ávila, Teresinha Gonçalves da Silva, Margareth de Fátima Formiga Melo Diniz, Marianna Vieira Sobral Castello-Branco   +13 more
doaj   +1 more source

Investigation of hemolytic activity of leptospirae on solid culture media.

, 2020
Results of investigation of hemolytic activity of leptospirae against red blood cells of various animal species on solid culture media using the technique of agar layers are presented.
Kiktenko V.S., Levina L.F., Soboleva G.L., Sarukhanova L.E., Volina E.G., Arutyunova G.A.   +5 more
core  

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao, Xudong Yu, Ziqian Shang, Mengyao Tan, Xie Huang, Zaizhi Du, Xiaojiao Wang, Xinrui Yang, Ximei Luo, Weidong Wang, Rong Li, Shenglin Luo   +11 more
wiley   +1 more source

Hemolytic activity.

, 2012
Hemolytic activities of Nile tilapia piscidin 1∼5 (TP1, -2, -3, -4, and -5) peptides against fish erythrocytes.
Shu-Hua Lee (114310), Chieh-Yu Pan (114318), Ai-Ling Hour (114314), Kuan-Chieh Peng (114307), Lin-Han Lee (114322), Jyh-Yih Chen (114328)   +5 more
core   +1 more source

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

A comparison of pneumolysin activity and concentration in vitro and in vivo in a rabbit endophthalmitis model

Clinical Ophthalmology, 2008
Melissa E Sanders1, Erin W Norcross1, Quincy C Moore III1, Chinwendu Onwubiko1, Lauren B King1,&nbsp;et al1Department of Microbiology; 2Department of Pathology, University of Mississippi Medical Center, Jackson, MS, USAAbstract: The purpose of this ...
Melissa E Sanders, Erin W Norcross, Quincy C Moore III, Chinwendu Onwubiko, Lauren B King, et al   +5 more
doaj  

Microangiopathic Hemolytic Anemia: A Rare Complication of Acute Pancreatitis

The Korean Journal of Gastroenterology
Microangiopathic hemolytic anemia (MAHA) is a rare subtype of hemolytic anemia characterized by elevated hemolytic markers and red blood cell destruction.
Syedda Ayesha, Masood Muhammad Karim, Maria Ali, Abdul Hadi Shahid, Salman Naseem Adil   +4 more
doaj   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source