Results 41 to 50 of about 47,838 (205)

Chemoenzymatic Synthesis of Enantiomeric, Bicyclic δ-Halo-γ-lactones with a Cyclohexane Ring, Their Biological Activity and Interaction with Biological Membranes

Biomolecules, 2020
Starting from 1-acetyl-1-cyclohexene, three enantiomeric pairs (ee ≥ 99%) of bicyclic δ-halo-γ-lactones with cyclohexane ring were obtained in five-step synthesis.
Marcelina Mazur, Aleksandra Włoch, Fouad Bahri, Hanna Pruchnik, Aleksandra Pawlak, Bożena Obmińska-Mrukowicz, Gabriela Maciejewska, Witold Gładkowski   +7 more
doaj   +1 more source

A Novel and Practical Synthesis of l-Hexoses from d-Glycono-1,5-lactones

, 2016
A novel and efficient conversion of d-glycono-1,5-lactones into the corresponding l-sugars is described. The important intermediate, δ-hydroxyalkoxamates, was provided by a practical alkoxyamination of d-glycono-1,5-lactones mediated by Me3Al.
Yoshinori Iwai (3008247), Shiro Ikegami (204666), Yuko Hitomi (1780504), Hideyo Takahashi (1621885)   +3 more
core   +1 more source

Deep Eutectic Solvents Based on Natural Ascorbic Acid Analogues and Choline Chloride

ChemistryOpen, 2020
Deep eutectic solvents (DES) are one of the most promising green technologies to emerge in recent years given their combination of environmentally friendly credentials and useful functionalities.
Andrew J. Maneffa, Dr. Adrian B. Harrison, Dr. Stewart J. Radford, Dr. A. Steve Whitehouse, Prof. James H. Clark, Dr. Avtar S. Matharu   +5 more
doaj   +1 more source

Sharpless Asymmetric Dihydroxylation: An Impressive Gadget for the Synthesis of Natural Products: A Review

Molecules, 2023
Sharpless asymmetric dihydroxylation is an important reaction in the enantioselective synthesis of chiral vicinal diols that involves the treatment of alkene with osmium tetroxide along with optically active quinine ligand.
Aqsa Mushtaq, Ameer Fawad Zahoor, Muhammad Bilal, Syed Makhdoom Hussain, Muhammad Irfan, Rabia Akhtar, Ali Irfan, Katarzyna Kotwica-Mojzych, Mariusz Mojzych   +8 more
doaj   +1 more source

1,2-Dioxines as Masked Cis γ-Hydroxy Enones and Their Versatility in the Synthesis of Highly Substituted γ-Lactones

, 2016
Addition of highly stabilized ester nucleophiles to 1,2-dioxines affords good to high yields of γ-lactones with high diastereoselectivity. Heterolytic or homolytic cleavage of the 1,2-dioxines under appropriate conditions generates the key reactive cis γ-
Dennis K. Taylor (1645621), Edward R. T. Tiekink (1550791), Ben W. Greatrex (1795870), Marc C. Kimber (1754752), Gary Fallon (3027507)   +4 more
core   +1 more source

Structural Characteristics of PON1 with Leu55Met and Gln192Arg Variants Influencing Oxidative-Stress-Related Diseases: An Integrated Molecular Modeling and Dynamics Study

Medicina, 2023
Background and Objectives: PON1 is a multi-functional antioxidant protein that hydrolyzes a variety of endogenous and exogenous substrates in the human system.
Sudhan M., Janakiraman V., Sheikh F. Ahmad, Sabry M. Attia, Talha Bin Emran, Rajesh B. Patil, Shiek S. S. J. Ahmed   +6 more
doaj   +1 more source

β‑Stereoselective Mannosylation Using 2,6-Lactones

, 2016
β-Stereoselective mannosylation using donors bearing the 2,6-lactone moiety is described. In general, glycosylation is a nucleophilic substitution reaction between an alcoholic nucleophile and a sugar moiety containing a leaving group at the anomeric ...
Kaname Sasaki (1894870), Yusuke Hashimoto (3330606), Saki Tanikawa (3330609), Ryota Saito (2065480)   +3 more
core   +1 more source

Intramolecular Lactones of Sialic Acids [PDF]

, 2020
The so-called “sialo-chemical-biology” has become an attractive research area, as an increasing number of natural products containing a sialic acid moiety have been shown to play important roles in biological, pathological, and immunological processes.
C. Pappone, Pietro Allevi, Paola Rota, P. Allevi, P. Rota, Carlo Pappone, P. La Rocca, Paolo La Rocca, L. Anastasia, Luigi Anastasia   +9 more
core   +2 more sources

Bidirectional cross metathesis and ring-closing metathesis/ring opening of a C2-symmetric building block: a strategy for the synthesis of decanolide natural products

Beilstein Journal of Organic Chemistry, 2013
Starting from the conveniently available ex-chiral pool building block (R,R)-hexa-1,5-diene-3,4-diol, the ten-membered ring lactones stagonolide E and curvulide A were synthesized using a bidirectional olefin-metathesis functionalization of the terminal ...
Bernd Schmidt, Oliver Kunz
doaj   +1 more source

Investigation of aroma carryover risk in a pilot plant and on industrial scale when bottling aromatised and subsequent regular wines on the same filling line

OENO One
Aromatised wine-based beverages and regular wines are commonly bottled on the same bottling line. Sealings installed in the bottling line absorb added aroma compounds from the aromatised wine-based beverages and a subsequent release of the absorbed aroma
Jörg Gottmann, David Müller, Jochen Vestner, Jens Schuster, Ulrich Fischer   +4 more
doaj   +1 more source