Results 31 to 40 of about 4,457 (157)
Tissue-Based Proteomic Profiling in Patients with Hyperplasia and Endometrial Cancer
Uterine cancers are among the most prevalent gynecological malignancies, and endometrial cancer (EC) is the most common in this group. This study used tissue-based proteomic profiling analysis in patients with endometrial cancer and hyperplasia, and ...
Khalid Akkour +10 more
doaj +1 more source
Mass spectrometry and bioinformatics analysis data
2DE and 2D-DIGE based proteomics analysis of serum from women with endometriosis revealed several proteins to be dysregulated. A complete list of these proteins along with their mass spectrometry data and subsequent bioinformatics analysis are presented ...
Mainak Dutta +12 more
doaj +1 more source
A proteomic analysis of serum-derived exosomes in rheumatoid arthritis
Background To understand the roles of serum exosomes in rheumatoid arthritis (RA), we comprehensively investigated the protein profiles of serum exosomes in patients with RA. Methods Exosomes were isolated from serum samples obtained from 33 patients (12
Hirotaka Tsuno +11 more
doaj +1 more source
Differentiating Two Closely Related Alexandrium Species Using Comparative Quantitative Proteomics
Alexandrium minutum and Alexandrium tamutum are two closely related harmful algal bloom (HAB)-causing species with different toxicity. Using isobaric tags for relative and absolute quantitation (iTRAQ)-based quantitative proteomics and two-dimensional ...
Bryan John J. Subong +3 more
doaj +1 more source
Hexokinase 2 (Hxk2) of Saccharomyces cerevisiae is a dual function hexokinase, acting as a glycolytic enzyme and being involved in the transcriptional regulation of glucose-repressible genes.
Henry Müller +4 more
doaj +1 more source
2D-DIGE for disease proteomics
Proteomic study is an effective approach in the disease research, because proteomic aberrations should exist behind any type of diseases and it is proteome that directly regulate the disease phenotypes. Two-dimensional difference gel electrophoresis (2D-DIGE) is a high performance proteomic technology.
openaire +2 more sources
Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain. [PDF]
Brain is a common site of breast cancer metastasis associated with significant neurologic morbidity, decreased quality of life, and greatly shortened survival.
Feng Li +6 more
doaj +1 more source
Opioid addiction is recognized as a chronic relapsing brain disease resulting from repeated exposure to opioid drugs. Cellular and molecular mechanisms underlying the ability of organism to return back to the physiological norm after cessation of drug ...
Hana Ujcikova +5 more
doaj +1 more source
Ocular Proteomics with Emphasis on Two-Dimensional Gel Electrophoresis and Mass Spectrometry
The intention of this review is to provide an overview of current methodologies employed in the rapidly developing field of ocular proteomics with emphasis on sample preparation, two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and mass ...
Mandal Nakul +4 more
doaj +1 more source
Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin. [PDF]
The development of novel targeted therapies has become an important research focus for lung cancer treatment. Our previous study has shown leptomycin B (LMB) significantly inhibited proliferation of lung cancer cells; however, p53 wild type lung cancer ...
Chuanwen Lu +4 more
doaj +1 more source

