Results 151 to 160 of about 698,678 (191)

Endolithic fungal diversity is present in the unique phosphatized rocks of an environmentally extreme equatorial archipelago revealed by DNA amplicon metagenomics. [PDF]

Braz J Microbiol
Rocha LBA, Gonçalves VN, de Oliveira FS, Corrêa GR, Senra EO, Duarte EB, Lopes FAC, Silva MC, Convey P, Câmara PEAS, Rosa LH.   +10 more
europepmc   +1 more source

Long‐Read Pan‐Cancer Transcriptomics Unravel Distinct Alteration Trends Between Gene and Isoform Expression in Tumorigenesis

iMetaMed, EarlyView.
Long‐read profiling of 144 tumor‐normal pairs identifies isoform‐level cancer dysregulation independent of gene changes. Our scoring system prioritizes isoform‐driven prognostic genes across cancers. ABSTRACT Tumorigenesis involves transcriptomic alterations at both gene and isoform levels.
Yuying Ding, Bo Wu, Dan Zhou, Qiang Li, Dingru Li, Mengyun Cai, Zhiyan Chen, Caimei Zhong, ChuanLe Xiao, Yuhua Deng   +9 more
wiley   +1 more source

LoL-align: sensitive and fast probabilistic protein structure alignment. [PDF]

Nat Methods
Reifenrath L, van Kempen M, Kim G, Kim SH, Radnezhad M, Gilchrist CLM, Mirdita M, Steinegger M, Söding J.   +8 more
europepmc   +1 more source

Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation

iNew Medicine, EarlyView.
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li, Chaoyang Wang, Junci Chong, Zishu Liu, Boying Wang, Shiyu Liu, Xingcai Zhang, Hengrui Liu, Shuanglin Qin, ChuTse Wu, Beidong Chen, Zhigang Chang   +11 more
wiley   +1 more source

Experimental Investigation of Puncture Behavior and Fractured Morphology of Steel/Graphene-Reinforced Polymer/Steel Sandwich Composite Structure. [PDF]

Polymers (Basel)
Anh VH, Duong NT, Thang VT.
europepmc   +1 more source

Artificial intelligence‐assisted nanozyme design for medical and environmental applications

Journal of Intelligent Medicine, EarlyView.
AI‐assisted nanozyme design integrates cross‐source data and machine learning to enable predictive structure‐activity relationships, accelerating intelligent diagnostics, precision therapeutics, and environmental surveillance. Abstract Nanozymes, a class of nanomaterials with intrinsic enzyme‐like catalytic activities, have emerged as promising ...
Xiaolin Guo, Hao Zhang, Zihan Zhao, Qingshan Liu, Jiayi Liu, Jiang Huang, Changlong Liu, Xiaoyu Mu   +7 more
wiley   +1 more source

ErisNet: A Deep Learning Model for Noise Reduction in CT Images. [PDF]

Bioengineering (Basel)
Mattiussi F, Magoga F, Cozzi A, Ferraro S, Cadei G, Martini C, Leu S, Khalifa EB, Azzena AA, Pileggi M, Rezzonico E, Rizzo S.   +11 more
europepmc   +1 more source

ChatBiobank: An AI‐Assisted Guidance Tool for Multi‐Omics Biobanking

Med Research, EarlyView.
ABSTRACT Omics‐based technologies have greatly advanced precision medicine, which relies on high‐quality biobanks to meet technical requirements. However, existing standards and technical resources address different components of biobanking, whereas integrated operational guidance connecting assay‐specific requirements, multimodal biospecimens ...
Zhao Sun, Xuejiao Xia, Rui Deng, Chang Sun, Yunfei Wang, Zhuohang Li, Jiahui Li, Guanghui Li, Mingliang Yuan, Sanfei Peng, Xiangyang Yin, Zhiwei Zhao, Xinhua Dong, Qi Liu, Jing‐Hua Yang, Zhen Yang, Yang Fu   +16 more
wiley   +1 more source