Results 121 to 130 of about 123,501 (158)

ChemInform Abstract: ALKYLATION AND SILYLATION OF 2H‐AZIRINES

Chemischer Informationsdienst, 1985
AbstractDas Azirin (I) wird zu (II) lithiiert, das mit elektrophilen Reagentien in der Seitenkette zu (III) substituiert wird.
P. F. BELLOIR, A. LAURENT, P. MISON, R. BARTNIK, S. LESNIAK   +4 more
openaire   +1 more source

An Accesss to 4,5,6-Trisubstituted Pyrimidines from 2H-Azirines and α-Isocyanoacetates or α-Isocyanoacetamides Enabled by 1,3-Dipolar [3 + 2] Cycloaddition/Ring-Expanding/Oxidative Aromatization Process.

Journal of Organic Chemistry
The products containing pyrimidine scaffolds exhibit various important physiological and biological activities. To date, the strategies to generate 4,5,6-trisubstituted pyrimidines were not reported.
Haoxiang Zhang, Mengfan Li, Kunpeng Wang, Yan Chen, Benren Liao, Qingwei Wang, Weiyin Yi   +6 more
semanticscholar   +1 more source

Recent approaches to the synthesis of 2H-azirines

Chemistry of Heterocyclic Compounds, 2019
The most recent (2013–2018) synthetic approaches toward 2H-azirine derivatives are summarized and discussed. This minireview covers the latest examples on the synthesis of 2H-azirines that can be gathered in five distinct categories: the Neber approach, decomposition of vinyl azides, ring contraction of isoxazoles, oxidative cyclization of enamine ...
Ramkumar N., Voskressensky L.G., Sharma U.K., Van Der Eycken E.V.   +3 more
openaire   +2 more sources

Strain Release Cycloadditions of 2H-Azirines: Access to Polycyclic Heterocycles.

Organic Letters
A strain release cycloaddition has been developed that exploits intermediate azirines formed via irradiation with blue LEDs. Subsequent cycloaddition with pyrones afforded novel aza-heterocycles (13 examples, 42%→66% yields).
Kévin Lebair, Kaitlin A Isfeld, Rebecca L Davis, T. Poisson, Shawn K. Collins   +4 more
semanticscholar   +1 more source

Nitrile Ylides and Nitrenes from 2H-Azirines

1982
2H-Azirines represent versatile substrates which can serve as useful precursors for the synthesis of other heterocyclic rings.1–7 An unusual feature of this three-membered heterocyclic ring is that it is susceptible to attack by both electrophilic and nucleophilic reagents.7 In addition, the 2π electrons present in the ring are known to participate in ...
Albert Padwa, Per H. J. Carlsen
openaire   +1 more source

ChemInform Abstract: REACTION OF 2H‐AZIRINES WITH NITRONES

Chemischer Informationsdienst, 1974
AbstractDiphenylazirin (I) reagiert mit den Isochinolin‐N‐oxiden (I) zu den Isochinolinen (III) und dem Diamid (IV).
A. PADWA, K. CROSBY
openaire   +1 more source

2H-Azirines as Synthetic Tools in Organic Chemistry

European Journal of Organic Chemistry, 2001
The versatility and the high synthetic potential including the asymmetric syntheses of 2H-azirines as valuable precursors for the preparation of a wide range of polyfunctional acyclic and cyclic compounds, is discussed.
Francisco Palacios, Ana María Ochoa de Retana, Eduardo Martínez de Marigorta, Jesús Manuel de los Santos   +3 more
openaire   +1 more source

ChemInform Abstract: Recent Advances in 2H‐Azirine Chemistry

ChemInform, 2013
AbstractReview: 173 refs.
Alexander F. Khlebnikov, Mikhail S. Novikov   +1 more
openaire   +1 more source

Activation/Cyclization of 2H‐Azirines and 3‐Amino‐2‐fluoropyridines Towards 2‐Aryl‐Pyrido[2,3‐b]pyrazines

Annalen der Pharmacie
The electrophilic activation of 2H‐azirines with triflic anhydride (Tf2O) for an addition/cyclization reaction producing 2‐aryl‐pyrido[2,3‐b]pyrazines regioselectively is described.
Tess Fortier, Audrey Belouin, Frédéric Vuillermet, Joanick Bourret, G. Pelletier   +4 more
semanticscholar   +1 more source

DMF as an amine source: iron-catalyzed cyclization of 2H-azirines to imidazoles.

Chemical Communications
A novel method has been developed for the synthesis of 1-methyl-4,5-diaryl-1H-imidazoles through Fe(II)-catalyzed cyclization of 2H-azirines and N,N-dimethylformamide (DMF) as an amine source.
Ming Zhao, Zi-Mo Yang, Liang Li
semanticscholar   +1 more source