Half‐Sandwich Organometallic Ir(III) and Ru(II) Compounds and their Interactions with Biomolecules
ChemPlusChem, Volume 90, Issue 4, April 2025.This review highlights how a Ir(III) and Ru(II) coordination complexes can change theirs cytotoxic activity by interacting with a biomolecules such as deoxyribonucleic acid (DNA), human albumins (HSA), nicotinamide adenine dinucleotide (NADH), and glutathione (GSH).
Sandra Kozieł +8 more
wiley +1 more source
Palladium-Catalyzed Synthesis of α-Carbonyl-α′-(hetero)aryl Sulfoxonium Ylides : Scope and Insight into the Mechanism [PDF]
, 2020 Despite recent advances, a general method for the synthesis of α-carbonyl-α′-(hetero)aryl sulfoxonium ylides is needed to benefit more greatly from the potential safety advantages offered by these compounds over the parent diazo compounds.
Aïssa, C. +4 more
core +2 more sources
Inflammaging and Immunosenescence in the Post‐COVID Era: Small Molecules, Big Challenges
ChemMedChem, Volume 20, Issue 6, March 15, 2025.The post‐COVID syndromes are strictly dependent from inflammaging and immunosenescence, for which the available treatments, particularly immunotherapy, have limited impact and safety issues. Alternative targets are under validation to disclose, besides anti‐inflammatory drugs, new small molecular entities able to counteract the imbalance of ...
Fabio Francavilla +6 more
wiley +1 more source
Formation of Synthetically Versatile 2-Aminobenzophenones from Readily Accessed Acyl Hydrazides [PDF]
, 2019 Herein, we report the transformation of readily accessed acyl hydrazides into protected 2-aminobenzophenones via a two-step process involving an aryne-based molecular rearrangement followed by a one-pot addition-elimination procedure. The assembly of the
Ahmed, N, Chudasama, V, Shamsabadi, A
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Chemistry &Biodiversity, Volume 22, Issue 3, March 2025.Abstract Diabetes mellitus (DM) is a metabolic condition that is a profound health concern across the globe due to its contribution to the increased mortality rate. It affects millions of people around the world and is associated with severe complications among people diagnosed with it.
Pule Seboletswe +6 more
wiley +1 more source
Photocatalyst-free light-mediated three-component alkoxy-, hydroxy-, and azidotrifluoromethylation of alkenes [PDF]
Photoinduced radical-polar crossover (RPC) reactions generally rely on the use of an external photocatalyst to generate the corresponding radical and ionic species, selected according to the redox potentials of the involved species. Herein, we describe a
Cabrera Afonso, María Jesús +6 more
core +2 more sources
Design and study of novel reactivities of alkynylazobenzenes [PDF]
Los heterociclos nitrogenados constituyen una clase de compuestos de gran importancia debido a sus propiedades y aplicaciones. Estos compuestos, desempeñan un papel fundamental en el campo de las ciencias de la vida, ya que están presentes en una gran ...
Mañas Hernández, Clara
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Transition-Metal-Free Direct C(sp3)-H Functionalization leading to Aza-γ-Carboline Alkaloid Analogues in Cascade Fashion [PDF]
, 2016 Iodine promoted cascade reaction has been developed for the synthesis of unrivalled Aza-γ-carboline alkaloid analogues via C-H functionalization of 2H-indazoles.
D S, Sharada, Ghosh, Ruma
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Novel Three-Step Synthesis of Imidazo[1,2-c]quinazoline-5(6H)-thione Derivatives [PDF]
, 2018 A novel synthesis of Iimidazo[1,2-c]quinazoline-5(6H)-thione framework was developed through a three-step reaction starting from benzil. The resulting (2-nitrophenyl)-4,5-diphenyl-1H-imidazole from the reaction of benzil and different 2 ...
S. Allameh, S. Nahavandian
core +1 more source
Fluoração de 2H-Indazoles [PDF]
Boletim da Sociedade Portuguesa de Química, 2021 openaire +1 more source