Results 171 to 180 of about 22,721 (206)
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Content of 3′,5′ cyclic AMP and cyclic AMP phosphodiesterase in dormant and activated tissues of Jerusalem artichoke tubers

Biochemical and Biophysical Research Communications, 1974
Abstract Using an highly sensitive and specific radioimmunoassay for 3′,5′ cyclic AMP, we have detected this cyclic nucleotide in partially purified extracts obtained from tuber tissues of Jerusalem artichoke. The level of cyclic AMP found in dormant tubers was very high compared with those of sprouting tubers and rapidly declines when dormant tissue
M, Giannattasio, E, Mandato, V, Macchia
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ChemInform Abstract: PENTASUBSTITUTED QUERCETIN ANALOGS AS SELECTIVE INHIBITORS OF PARTICULATE 3′,5′‐CYCLIC‐AMP PHOSPHODIESTERASE FROM RAT BRAIN

Chemischer Informationsdienst, 1983
AbstractQuercetin (Ia) reagiert mit Alkyl‐sulfaten und ‐iodiden sowie Carbonsäureanhydriden zu den Derivaten (II), (III) und (VI), von denen (VI) in die Ether (VII) übergeführt wird.
M. PICQ   +4 more
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The involvement of the 3?:5?-cyclic-AMP phosphodiesterase in transformation and growth of crown-gall tumors in Bryophyllum daigremontianum

Planta, 1977
In crown-gall tumor tissue obtained from leaves of Bryophyllum daigremontianum an adenosine 3':5'-cyclic phosphate (3':5'-cyclic-AMP) degrading activity increases up to 2.5 fold until the fifth day after inoculation with Agrobacterium tumefaciens, declining to the value of the control in the solid tumor. Theophylline up to 1 mmol l(-1) given to wounded
H D, Frey, V, Kirchhoff, A, Brennicke
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Rapid assays for adenylate cyclase and 3′, 5′ cyclic AMP phosphodiesterase activities. Simultaneous measurements of other pathways of ATP catabolism

Analytical Biochemistry, 1974
Abstract This paper deals with a rapid assay of adenylate cyclase activity and 3′,5′ cyclic AMP phosphodiesterase activity which permits simultaneous measurements of other pathways of ATP catabolism. The separation of all the adenylic nucleotides was obtained by an electrophoresis on cellulose acetate 15 min at 50 V/cm with a fluorescent buffer pH 8 ...
M A, Delaage, B N, Bellon, H L, Cailla
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Axonal Transport of the Ca2+‐Dependent Protein Modulator of 3′:5′‐Cyclic‐AMP Phosphodiesterase in the Rabbit Visual System

Journal of Neurochemistry, 1980
Abstract: Water‐soluble proteins were extracted from individual retinas, optic nerves, combined optic tracts and lateral geniculate bodies, and superior colliculi of rabbits at 1, 3, and 18 days after injection of [3H]leucine into the right eye. The Ca2+‐dependent protein modulator of 3′:5′‐cyclic‐AMP phos‐phodiesterase (calmodulin) was isolated from ...
P F, Erickson   +4 more
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Properties of 3',5'-cyclic-AMP phosphodiesterase from Paragonimus africanus metacercariae.

Tropenmedizin und Parasitologie, 1976
3',5'-Cyclic-AMP 5'-nucleotidohydrolase (cAMP phosphodiesterase, EC 3.1.4.17) was partial purified from metacercariae of Paragonimus africanus. The enzyme activity absolutely depends on Mg2 or Mn2+. The pH-optimum of the cAMP phosphidiesterase was found at pH 8.0. The Michaelis constant for cAMP was determined to be 5 X 10(-6) M.
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Possible participation of glucocorticoid in elevation of 3',5'-cyclic AMP levels through inhibition of cyclic AMP phosphodiesterase.

Physiological chemistry and physics, 1979
Administration of prednisolone and cholate to rats elevated levels of cAMP (adenosine 3',5'-cyclic monophosphate) by 1.5- to 2.0-fold. Compounds such as prednisolone, hydrocortisone, cholate, and deoxycholate were found to be potent inhibitors of partially purified cAMP phosphodiesterase prepared from rat liver.
Y, Tanigawa   +6 more
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3-Substituted 5,7-dimethylpyrazolo[1,5-a]pyrimidines, 3',5'-cyclic AMP phosphodiesterase inhibitors

Journal of Medicinal Chemistry, 1974
Thomas Novinson   +5 more
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