Results 101 to 110 of about 7,931 (260)

Synthesis of an Enzyme‐Triggered Chitosan‐Based Drug Delivery System for Peri‐Implantitis Prevention

Chemistry – A European Journal, Volume 32, Issue 16, 25 April 2026.
ABSTRACT Dental implants have become a leading solution for tooth loss, yet bacterial infections remain a major complication. Antibacterial implant coatings are an important approach to reduce or prevent bacterial infections at the implant. Given the oral cavity's complex microbiome and the importance of some commensal bacteria, it is crucial to ...
Nelly Senze Nnane, Amit Gaikwad, Muhammad Imran Rahim, Andreas Winkel, Oliver Hergert, Till Beuerle, Meike Stiesch, Henning Menzel   +7 more
wiley   +1 more source

Stereodivergent, Diels-Alder-initiated organocascades employing α,β-unsaturated acylammonium salts: scope, mechanism, and application. [PDF]

, 2017
Chiral α,β-unsaturated acylammonium salts are novel dienophiles enabling enantioselective Diels-Alder-lactonization (DAL) organocascades leading to cis- and trans-fused, bicyclic γ- and δ-lactones from readily prepared dienes, commodity acid chlorides ...
Abbasov, Mikail E, Hudson, Brandi M, Romo, Daniel, Tantillo, Dean J   +3 more
core   +2 more sources

A combined experimental and theoretical study of the polar [3+2] cycloaddition of electrophilically activated carbonyl ylides with aldehydes and imines [PDF]

, 2009
International audienceNumerous 2,5-diaryl-1,3-dioxolane-4,4-dicarbonitriles and 2,4-diphenyl-1,3-oxazolidine-5,5- dicarbonitriles have been synthesized by [3+2] cycloaddition reactions between carbonyl ylides generated from epoxides, and aldehydes or ...
Bentabed-Ababsa, Ghenia, Chamorro, Edouardo, Derdour, Aicha, Domingo, Luis .R., Mongin, Florence, Pérez, Patricia, Roisnel, Thierry, Saez, José A.   +7 more
core   +3 more sources

Formation of Pyrazol-1,3,4-Thiadiazoles through 1,3-Dipolar Cycloadditions of 3-Thioxo-[1,2,4]-Triazepin-5-one with Nitrilimines: An Experimental and Computational study [PDF]

, 2009
In this work the results of experimental and computational study of the title compounds and some ancillary compounds are reported. Two bicyclic pyrazol-1,3,4-thiadiazole derivatives were synthesized by reaction between 6-dimethylaminomethylene-3-thioxo-
Azzouzi, S., Domingo, Luis R., El Messaoudi, M., Esseffar, M., Jalal, R., Latorre, J., Liu González, M., Sáez Cases, José Antonio   +7 more
core   +2 more sources

Eugenol‐Derived Sustainable Cyclic Carbonates and Polythiocarbonates from CO2 and COS as Efficient Hybrid Catalysts for Suzuki–Miyaura Cross‐Coupling Reactions

Advanced Sustainable Systems, Volume 10, Issue 4, April 2026.
A bio‐based palladium‐ligated polymer catalyst was achieved through COS/eugenol‐epoxide copolymerization and post‐polymerization functionalisation using click chemistry. The resulting hybrid catalyst efficiently catalyses Suzuki cross‐coupling reactions at low catalyst loadings with excellent recyclability.
Mohsin Hassan, Gulzar A. Bhat, Donald J. Darensbourg   +2 more
wiley   +1 more source

Microwave-assisted generation and reactivity of aza- and diazafulvenium methides: heterocycles via pericyclic reactions [PDF]

, 2008
Azafulvenium methides and diazafulvenium methides have been generated under microwave irradiation from 2,2-dioxo-1H,3H-pyrrolo[1,2-c]thiazoles and 2,2-dioxo-1H,3H-pyrazolo[1,5-c]thiazoles, respectively.
Melo, Teresa M. V. D. Pinho e, Soares, Maria I. L.   +1 more
core   +1 more source

Spatial Control Over Tether‐Tunable Coordination on Palladium for Divergent Synthesis of Bicyclo[n.1.0]alkanes via Oxidative Cyclopropanation of Enynes

Advanced Science, Volume 13, Issue 19, 2 April 2026.
We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley   +1 more source

Reaction Mechanisms of Transition-Metal-Catalyzed Azide-Alkyne Cycloaddition “Click” Reactions: A DFT Investigation

, 2015
International audienceDFT calculations at the PBE0/LANL2DZ level have been performed on model compounds to investigate the reaction mechanism of two recently reported metal-catalyzed alkyne azide cycloaddition (MAAC).
Astruc, Didier, Ikhlef, Djamila, Kahlal, Samia, Maouche, Boubekeur, Saillard, Jean-Yves, Wang, Changlong   +5 more
core   +3 more sources

Synthetic Cathepsin B Sensitive Adjuvant‐Peptide Conjugates to Target Intracellular Toll‐Like Receptors 7 and 8

ChemistryEurope, Volume 4, Issue 4, April 2026.
Cathepsin B‐sensitive peptide–adjuvant conjugates are designed, synthesized, and evaluated to deliver an antigenic peptid and an adjuvant targeting Toll‐like receptors 7 and 8 (TLR7/8) to antigen presenting cells. The adjuvant is released by cathepsin B resulting in antigen presentation and TLR mediated T cell activation.
Marjolein M. E. Isendoorn, Giulia Castello, Nico J. Meeuwenoord, Martijn Verdoes, Jeroen D. C. Codée, Ferry Ossendorp, Dmitri V. Filippov   +6 more
wiley   +1 more source

1, 3-Dipolar Cycloaddition of Diazomethane with Carbon-Carbon Unsaturated Systems Involving Nitrofuran Ring

Journal of Synthetic Organic Chemistry, Japan, 1968
1, 3-Dipolar cycloaddition reaction of diazomethane with 5-nitro-2-furylacrylic acid gave 4- (5'-nitro-2'-furyl) -3-carbomethoxypyrazoline (3), mp 184485°C, in 80% yield. A similar reaction with 5-nitro-2-furylpropiolic acid afforded the corresponding isomeric mixture of the 2-pyrazole derivatives in 25% yield. (1) was refluxed in toluene to afford 2- (
Tadashi SASAKI, Katsuhiko SHOJI
openaire   +2 more sources